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Autor:
Thais Lopes Valentim Di Paschoale Ostolin, Alexandre Barbosa Reis, Bruno Mendes Roatt, Rory Cristiane Fortes de Brito, Fernando Augusto Siqueira Mathias, Frédéric Frézard, Guilherme Santos Ramos, Jamille Mirelle de Oliveira Cardoso, Hélida Monteiro de Andrade, João Filipe Pereira Vieira, Rodrigo Dian de Oliveira Aguiar-Soares, Levi Eduardo Soares Reis
Publikováno v:
Molecular Immunology. 141:70-78
This study compared the therapeutic potential of the chemotherapy using meglumine antimoniate encapsulated in a mixture of conventional and PEGylated liposomes (Nano Sbv) and immunotherapy with anti-canine IL-10 receptor-blocking monoclonal antibody
Autor:
Nargis Khan, Javed N. Agrewala, Susanta Pahari, Sanpreet Singh, Kanupriya Sethi, Sudeep K. Maurya, Mohammad Aqdas, Gurpreet Kaur
Publikováno v:
ACS Infectious Diseases. 7:2999-3008
Tuberculosis (TB) treatment is lengthy and inflicted with severe side-effects. Here, we attempted a novel strategy to reinforce host immunity through NOD-like receptor (NOD-2) and Toll-like receptor (TLR-4) signaling in the murine model of TB. Intrig
Autor:
Huan Peng, Wei Wang, Lijun Bi, Xin Zhang, Yan Li, Ma Wenjing, Wang Yaguo, Liqun Zhang, Shilin Qu, Kewei Liu
Publikováno v:
Journal of Biomedical Nanotechnology. 17:2034-2042
Tuberculous meningitis (TBM) is an incurable disease with high mortality. It is an extrapulmonary tuberculosis caused by mycobacterium tuberculosis which penetrated the blood-brain barrier and infected the meninges. Mycobacterium tuberculosis lurking
Publikováno v:
Immunopharmacology and Immunotoxicology. 43:767-777
Atopic dermatitis (AD) is a pruritic, chronic, relapsing inflammatory skin disease. The research aims to study the effects of Sarsasapogenin and its combination with Fluticasone in 2, 4-Dinitrofluorobenzene (DNFB) induced atopic dermatitis in BALB/c
Publikováno v:
Tropical Medicine & International Health. 26:1634-1644
Objectives The aims of the study are twofold: (1) antigen (Ag) preparation and evaluation of three antigens of Gnathostoma spinigerum infective larvae (GsL3), crude somatic antigen (CSAg), excretory-secretory antigen (ESAg), and partially purified an
Publikováno v:
Vaccine. 39:5580-5588
Schistosomiasis is an important fresh-water-borne parasitic disease caused by trematode worms of the genus Schistosoma. With > 250 million people infected worldwide and approximately 800 million people at risk, the World Health Organization considers
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 156-167 (2021)
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 156-167 (2021)
Cryptosporidiosis has been considered as a serious diarrheal disease, especially in immunodeficient patients, where they failed to clear the infection leading to several consequences of infection (i.e death). The role of cell mediated immunity in cle
Autor:
Kentaro Oka, Mao Hagihara, Yusuke Koizumi, Shuhei Eguchi, Tadashi Ariyoshi, Seiya Higashi, Yuka Yamagishi, Makoto Yamashita, Tsunemasa Nonogaki, Yasutoshi Kuroki, Motomichi Takahashi, Kenta Iwasaki, Takeshi Mori, Hiroshige Mikamo, Nobuhiro Asai
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
Clostridioides difficile infection (CDI) represents the leading cause of nosocomial diarrhea worldwide and is associated with gut dysbiosis and intestinal damage. Clostridium butyricum MIYAIRI 588 (CBM 588) contributes significantly to reduce epithel
Autor:
Christine Quach, Lauriane Galle-Treger, Omid Akbari, Emily Howard, Doumet Georges Helou, Richard Lo, Marshall Fung, Benjamin P. Hurrell, Pedram Shafiei-Jahani, Hooman Allayee, Jacob D. Painter
Publikováno v:
Mucosal immunology
Allergic asthma is a chronic inflammatory disorder associated with airway hyperreactivity (AHR) whose global prevalence is increasing at an alarming rate. Group 2 innate lymphoid cells (ILC2s) and T helper 2 (TH2) cells are producers of type 2 cytoki
Autor:
Zhaoyu Chen, Zhumin Su, Xiaohong Chen, Donghong Li, Liping Shen, Xiuli Lin, Xueying Ma, Hao Chen, Yingying Liu, Lili Ma, Xiaomeng Ma
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Constipation is a common gastrointestinal dysfunction which has a potential impact on people's immune state and their quality of life. Here we investigated the effects of constipation on experimental autoimmune encephalomyelitis (EAE), an