Zobrazeno 1 - 10
of 3 703
pro vyhledávání: ''
Publikováno v:
Bioengineered, Vol 12, Iss 2, Pp 11947-11958 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
Type 2 diabetes mellitus (T2DM) is known as a complex genetic disease characterized by genetic and environmental factors. The imbalanced intestinal flora and intestinal mucosal barrier are considered to be related to T2DM. Curcumin has been proved to
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 20:975-981
Background: Obsessive-Compulsive Disorder (OCD) is an intricate, debilitating neuropsychiatric disorder. Exclusively, Selective Serotonin Reuptake Inhibitors (SSRIs) are effective agents used for the treatment of OCD. However, SSRIs are not a magic p
Autor:
Ajib Diptyanusa, Ika Puspa Sari
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 17, Iss, Pp 128-138 (2021)
International Journal for Parasitology: Drugs and Drug Resistance
International Journal for Parasitology: Drugs and Drug Resistance
The global burden of diarrhea caused by Cryptosporidium parasite is underestimated. In immunocompromised hosts, chronic and severe presentation of intestinal cryptosporidiosis can result in long-term morbidity and high illness costs. The evidence of
Autor:
Xin Min Liu, Yi Wen Zhang, Hong Huang, Ning Jiang, Cong Lu, Hai Xia Wang, Jing Lv, Guang Hua Lu
Publikováno v:
Life Sciences in Space Research. 31:51-58
Circadian rhythm disorder (CRD) in space flight can lead to memory impairment, performance decrements and adverse health outcomes, the main manifestations of which are circadian desynchronization, sleep loss and insomnia. Sleep deprivation (SD) provi
Autor:
Ying Han, Xingxing Wang, Xuanxuan Liu, Li Zhao, Shuo Sun, Haiyang Tang, Changlei Bao, Ang Luo, Yan Pan
Publikováno v:
Drug Design, Development and Therapy
Purpose Endothelial dysfunction and the subsequent decrease in endothelium-dependent vascular relaxation of small arteries are major features of hypertension. Artemisinin, a well-known antimalarial drug, has been shown to exert protecting roles again
Autor:
Jane Kabwe, Hirofumi Sawada, Masako Kawai, Kazuo Maruyama, Ayumu Yokochi, Yoshihide Mitani, Amphone Okada, Ayaka Omori, Toshikazu Ito, Junko Maruyama, Erquan Zhang
Publikováno v:
BMC Pulmonary Medicine, Vol 21, Iss 1, Pp 1-17 (2021)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Preventing pulmonary vascular remodeling is a key strategy for pulmonary hypertension (PH). Causes of PH include pulmonary vasoconstriction and inflammation. This study aimed to determine whether cilostazol (CLZ), a phosphodiesterase-3 inh
Publikováno v:
International Journal of Biological Macromolecules. 189:346-355
Finasteride is an antiandrogenic drug used for the clinical treatment of chronic nonbacterial prostatitis (CNP). Recently, we reported the anti-CNP activity of Poria cocos polysaccharides (PPs) in a rat model. In this study, we compared the differenc
Autor:
Huan Peng, Wei Wang, Lijun Bi, Xin Zhang, Yan Li, Ma Wenjing, Wang Yaguo, Liqun Zhang, Shilin Qu, Kewei Liu
Publikováno v:
Journal of Biomedical Nanotechnology. 17:2034-2042
Tuberculous meningitis (TBM) is an incurable disease with high mortality. It is an extrapulmonary tuberculosis caused by mycobacterium tuberculosis which penetrated the blood-brain barrier and infected the meninges. Mycobacterium tuberculosis lurking
Autor:
Lingling Song, Junming Wang, Ying Cui, Xiaohui Wu, Can Cao, Zhang Yueyue, Chen Liu, Yuechen Guan
Publikováno v:
Neuroscience. 473:102-118
Depression has huge social risks of high incidence, disability, and suicide. Its prevalence and harm in people with hyperglycemia are 2–3 times higher than in normal people. However, antidepressants with precise curative effects and clear mechanism
Publikováno v:
Immunopharmacology and Immunotoxicology. 43:767-777
Atopic dermatitis (AD) is a pruritic, chronic, relapsing inflammatory skin disease. The research aims to study the effects of Sarsasapogenin and its combination with Fluticasone in 2, 4-Dinitrofluorobenzene (DNFB) induced atopic dermatitis in BALB/c