Zobrazeno 1 - 10
of 489
pro vyhledávání: '"Ochi A"'
Autor:
Arisa Ochi, Yasumasa Ikeda, Naoki Kashihara, Kojiro Nagai, Kensei Taguchi, Masanori Tamaki, Ken-ichi Aihara, Hideharu Abe, Masashi Miyoshi, Craig R. Brooks, Hiroyuki Kadoya, Kenji Nishimura, Seiji Kishi
Publikováno v:
Biochemical and Biophysical Research Communications. 556:142-148
The relationship between cellular senescence and fibrosis in the kidney is being elucidated and we have identified it as therapeutic target in recent studies. Chronic kidney disease has also become a lifestyle disease, often developing on the backgro
Publikováno v:
Proceedings of the Japan Academy. Series B, Physical and Biological Sciences
Neural stem cells (NSCs) actively proliferate and generate neurons and glial cells (active state) in the embryonic brain, whereas they are mostly dormant (quiescent state) in the adult brain. The expression dynamics of Hes1 are different between acti
Autor:
Poomraphie Nuntawong, Shinji Wada, Taiki Horikawa, Seiichi Sakamoto, Satoshi Morimoto, Hiroyuki Tanaka, Yumi Tsuneura, Akihiro Ochi
Publikováno v:
Phytochemical Analysis. 32:512-520
Introduction Swertia japonica Makino (S. japonica) has a long history of use as a folk medicine, and it is one of the three essential Japanese folk medicines. S.japonica has been reported to have various biological activities. The biologically active
Autor:
Juan A. Kochen Rossi, Ankita Mishra, Berk Aykut, Mautin Hundeyin, Deirdre Jill Cohen, Ece Bagdatlioglu, Atsuo Ochi, Wenyu Su, Joshua Leinwand, Pamela Nassau, Narendra Verma, Mohammed Khan, Jacqueline I. Kim, Nan Wu, Michael Reilly, James H. Thorpe, Aarif Ahsan, Fei Li, Varshini Vasudevaraja, George Miller, Allison M. Beal, Ting Chen, Wei Wang, John D. Lich, Pardeep S. Taunk, Mukesh K. Mahajan, Inedouye Yaboh, Dennis Adeegbe, Jingjing Wu, Philip A. Harris, John Bertin, Johana Gutierrez, Kwok-Kin Wong, Brian Diskin, Emma Kurz, Yue Wu, Christina Almonte, J. Mosley, Michael Glacken, Jill M. Marinis, Shivraj Savadkar
Publikováno v:
Cancer Cell. 38:585-590
Summary Pancreatic ductal adenocarcinoma (PDA) is characterized by immune tolerance and immunotherapeutic resistance. We discovered upregulation of receptor-interacting serine/threonine protein kinase 1 (RIP1) in tumor-associated macrophages (TAMs) i
Autor:
Shuko Nojiri, Katsumi Miyahara, Naho Fujiwara, Masahiko Urao, Takanori Ochi, Ryo Sueyoshi, Chihiro Akazawa, Nana Nakazawa-Tanaka, Atsuyuki Yamataka
Publikováno v:
Pediatric Surgery International. 36:43-48
Interactions between enteric neural crest-derived cells (ENCC) and the surrounding intestinal microenvironment, such as the extracellular matrix (ECM), are critical for regulating enteric nervous system (ENS) development. Integrins are the major rece
Publikováno v:
In vivo (Athens, Greece). 33(5):1477-1484
Background/Aim: Leukocyte activation is thought to be a major step in sepsis-induced pulmonary edema. We attempted to confirm whether pulmonary edema can be reproduced under intravital microscopy in a model of transfusion-related acute lung injury (T
Autor:
Masanori Tamaki, Sayo Ueda, Kojiro Nagai, Kenji Nishimura, Shu Wakino, Akiko Sakurai, Arisa Ochi, Eriko Shibata, Tatsuya Tominaga
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
p16 inhibits cyclin-dependent kinases and regulates senescence-mediated arrest as well as p21. Nuclear p16 promotes G1 cell cycle arrest and cellular senescence. In various glomerular diseases, nuclear p16 expression is associated with disease progre
Publikováno v:
Toxins, Vol 13, Iss 272, p 272 (2021)
Toxins
Volume 13
Issue 4
Toxins
Volume 13
Issue 4
Clostridium botulinum C2 toxin is a clostridial binary toxin consisting of actin ADP-ribosyltransferase (C2I) and C2II binding components. Activated C2II (C2IIa) binds to cellular receptors and forms oligomer in membrane rafts. C2IIa oligomer assembl
Autor:
Hiroshi Fujiwara, Kazushi Tanimoto, Katsuto Takenaka, Masaki Maruta, Junya Masumoto, Toshiki Ochi, Mie Kurata, Masaki Yasukawa, Fumitake Kondo, Toshihiro Yamamoto
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Communications Biology
Communications Biology
Cancer immunotherapy using T cells redirected with chimeric antigen receptor (CAR) has shown a lot of promise. We have established a single-chain antibody (scFv) generation system in which scFv library-expressing CAR-T cells can be screened appropria
Environmental oxygen exposure allows for the evolution of interdigital cell death in limb patterning
Autor:
Keijiro Munakata, Mikiko Tanaka, Mara Laslo, Kaori Kabashima, Chika Nishimori, Haruki Ochi, Ingrid Rosenburg Cordeiro, James Hanken
Publikováno v:
Developmental Cell. 50:155-166
Summary Amphibians form fingers without webbing by differential growth between digital and interdigital regions. Amniotes, however, employ interdigital cell death (ICD), an additional mechanism that contributes to a greater variation of limb shapes.