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Autor:
Xi Yang, Yulai Zhou, Huan Li, Fuzhen Song, Juan Li, Yong Zhang, Yi Lin, Huijuan Zhang, Jianxia Fan, Weibin Wu
Publikováno v:
Journal of Cellular Physiology. 237:3080-3094
Intrahepatic cholestasis of pregnancy (ICP) is a common pregnancy-specific disease, characterized by increased bile acid levels and adverse fetal outcomes. We previously reported excessive bile acids led to dysfunction of placental trophoblasts in IC
Publikováno v:
Journal of Molecular Histology. 53:493-502
Echinacoside is a group of natural compounds extracted from medicinal plants Cistanche and Echinacea, which has neuroprotective, antiaging, immunomodulatory and anticancer effects, but its specific role and mechanism in tumor remains partially unclea
Autor:
Shujie Wang, Gang Wang, Yan-Dong Tang, Siqi Li, Lei Qin, Menghang Wang, Yong-Bo Yang, Marcelo Gottschalk, Xuehui Cai
Publikováno v:
Microbiology Spectrum. 10
Little is known about the damage to the important peripheral immune organ spleen caused by Streptococcus suis infection. In this study, we found that S. suis induced splenomegaly and lymphocyte disruption in spleens of mice. To explore the mechanism
Publikováno v:
Journal of Cellular Physiology. 237:868-880
Diabetic retinopathy (DR) is a common complication of diabetes mellitus. High glucose-induced mitochondrial apoptosis is involved in the loss of retinal pericytes (PCs), which is considered to be a predominant pathologic change of diabetic retinopath
Publikováno v:
Journal of Bioenergetics and Biomembranes. 53:513-523
The poor outcomes in retinoblastoma necessitate new treatments. Salinomycin is an attractive candidate, and has demonstrated selective anti-cancer properties in different cancer types. This work addressed the efficacy of salinomycin in retinoblastoma
Publikováno v:
Journal of Molecular Histology. 52:1007-1020
Glioma remains the most common malignant tumors in the central nervous system and often has poor prognosis. In recent years, it has been gradually revealed that non-coding RNA effects glioma progression. In this study, we aimed to investigate the sig
Publikováno v:
Clinical and Experimental Nephrology. 25:1182-1192
Tubular injury plays a crucial role in the pathogenesis of diabetic nephropathy (DN). It is well known that many microRNAs (miRNAs) exert crucial effects on tubular injury. This study intends to explore the effect of miR-142-3p on the apoptosis and o
Autor:
Erxiong Liu, Yutong Chen, Jinmei Xu, Shunli Gu, Ning An, Jiajia Xin, Wenting Wang, Zhixin Liu, Qunxing An, Jing Yi, Wen Yin
Publikováno v:
Microbiology spectrum. 10(4)
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most common drug-resistant bacteria and poses a significant threat to human health. Due to the emergence of multidrug resistance, limited drugs are available for the treatment of MRSA i
Autor:
Gi Uk Jeong, Jaemyun Lyu, Kyun-Do Kim, Young Cheul Chung, Gun Young Yoon, Sumin Lee, Insu Hwang, Won-Ho Shin, Junsu Ko, June-Yong Lee, Young-Chan Kwon
Publikováno v:
Microbiology Spectrum. 10
Accumulating evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes various neurological symptoms in patients with coronavirus disease 2019 (COVID-19). The most dominant immune cells in the brain are micr
Publikováno v:
Reproduction. 161:295-306
Nilotinib is a second-generation tyrosine kinase inhibitor (TKI) that is widely used to treat patients with Philadelphia chromosome-positive chronic myeloid leukaemia (CML). TKIs provided a significant improvement in terms of survival rates and disea