Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jingwu Xie"'
Publikováno v:
Journal of Genetics and Genomics. 44:375-383
Gastric cancer is a leading cause of cancer-related mortality worldwide, and options to treat gastric cancer are limited. Fluorouracil (5Fu)-based chemotherapy is frequently used as a neoadjuvant or an adjuvant agent for gastric cancer therapy. Most
Publikováno v:
Oncogene. 29:469-481
The hedgehog pathway, initially discovered by two Nobel laureates Drs E Wieschaus and C Nusslein-Volhard in Drosophila, is a major regulator for cell differentiation, tissue polarity and cell proliferation. Studies from many laboratories reveal activ
Autor:
Dongsheng Gu, Jingwu Xie
Publikováno v:
Cancers
Cancers, Vol 7, Iss 3, Pp 1684-1698 (2015)
Cancers, Vol 7, Iss 3, Pp 1684-1698 (2015)
As a major regulatory pathway for embryonic development and tissue patterning, hedgehog signaling is not active in most adult tissues, but is reactivated in a number of human cancer types. A major milestone in hedgehog signaling in cancer is the Food
Autor:
Kai Chen, Patrick A. Adegboyega, Jing He, Jingwu Xie, Xiaoli Zhang, Josh Sultz, Xiaoli Ma, Shuhong Huang, Yuanxin Zhang, Tao Sheng, Hongwei Zhang
Publikováno v:
International Journal of Cancer. 118:139-148
The hedgehog pathway plays a critical role in the development of the foregut. However, the role of the hedgehog pathway in primary esophageal cancers is not well studied. Here, we report that elevated expression of hedgehog target genes occurs in 14
Autor:
Xiaoli Zhang, Sumin Chi, Stephen K. Tyring, Oivin Guicherit, Jingwu Xie, Chengxin Li, Richard F. Wagner, Nonggao He
Publikováno v:
Oncogene. 23:1608-1617
Basal cell carcinoma (BCC), the most common form of human cancer, is understood to be associated with activation of the sonic hedgehog pathway, through loss-of-function mutations of tumor suppressor PTCH1 or gain-of-function mutations of smoothened.
Autor:
Jingwu Xie
Publikováno v:
Hedgehog signaling activation in human cancer and its clinical implications
Hedgehog signaling activation in human cancer and its clinical implications , Hedgehog signaling activation in human cancer and its clinical implications , کتابخانه مرکزی دانشگاه علوم پزشکی تهران
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18977486a0444f7d8f0f6fa6c075a2f9
https://doi.org/10.1007/978-1-4419-8435-7
https://doi.org/10.1007/978-1-4419-8435-7
Publikováno v:
Cell Research. 3:147-156
Anti-keratin monoclonal antibody AF5 was introduced into fertilized eggs of Xenopus laevis., and its effects on embryonic development were studied. Survival rate of the antikeratin-injected embryos was much lower (only 35.76% at gastrula) than that o
Autor:
Shuhong Huang, Xiaoli Zhang, Ling Yang, Jingwu Xie, Nonggao He, Jing He, Yuehong Bian, Hongwei Zhang
Publikováno v:
Molecular Cancer
Molecular Cancer, Vol 8, Iss 1, p 112 (2009)
Molecular Cancer, Vol 8, Iss 1, p 112 (2009)
The hedgehog (Hh) signaling pathway regulates many processes of development and tissue homeostasis. Activation of hedgehog signaling has been reported in about 30% of human cancer including ovarian cancer. Inhibition of hedgehog signaling has been pu
Publikováno v:
World journal of gastroenterology. 12(25)
To study the expression of Sonic hedgehog pathway-related molecules, Sonic hedgehog (Shh) and Gli1 in gastric carcinoma.Expression of Shh in 56 gastric specimens including non-cancerous gastric tissues, gastric adenocarcinoma, gastric squamous cell c
Autor:
Xiaoli Zhang, Yuehong Bian, Arwen A. Stelter, Ling Yang, Kefei Zhang, Jingwu Xie, Shuhong Huang, Wendell W. Tang, Qian Wang, Jing He, Guorui Xie, Hongwei Zhang
Publikováno v:
Carcinogenesis. 27(7)
Liver cancers, the majority of which are hepatocellular carcinomas (HCCs), rank as the fourth in cancer mortality worldwide and are the most rapidly increasing type of cancer in the United States. However, the molecular mechanisms underlying HCC deve