Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sarmistha Nanda"'
Autor:
Raksha Bhat, Hariprasad Thangavel, Noor Mazin Abdulkareem, Suhas Vasaikar, Carmine De Angelis, Leon Bae, Maria Letizia Cataldo, Sarmistha Nanda, Xiaoyong Fu, Bing Zhang, Rachel Schiff, Meghana V. Trivedi
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
G Protein-Coupled Receptors (GPCRs) represent the largest superfamily of cell-surface proteins. However, the expression and function of majority of GPCRs remain unexplored in breast cancer (BC). We interrogated the expression and phosphorylation stat
Autor:
Hariprasad Thangavel, Rachel Schiff, Sarmistha Nanda, Meghana V. Trivedi, Suhas Vasaikar, Bing Zhang, Carmine De Angelis, Martin Shea, Raksha Bhat, Ambily Gopinathan, Lanfang Qin, Tamika Mitchell, Noor Mazin Abdulkareem
Publikováno v:
FASEB J
While G protein-coupled receptors (GPCRs) are known to be excellent drug targets, the second largest family of adhesion-GPCRs is less explored for their role in health and disease. ADGRF1 (GPR110) is an adhesion-GPCR and has an important function in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1978c6f1b6b1ab1102718017162bc67f
https://europepmc.org/articles/PMC8218746/
https://europepmc.org/articles/PMC8218746/
Autor:
Dharmendra K. Bhargava, P Yadav, Vihang A. Narkar, Debashish Sahay, Raksha Bhat, Carmine De Angelis, Meghana V. Trivedi, Vikas Yadav, Sahar Yazdanfard, Ahmed Al-rawi, C. Kent Osborne, Lanfang Qin, Xiaoyong Fu, Chad J. Creighton, Sarmistha Nanda, Vidyalakshmi Sethunath, Rachel Schiff
PURPOSE: G protein-coupled receptors (GPCRs) represent the largest family of druggable targets in human genome. Although several GPCRs can cross-talk with the human epidermal growth factor receptors (HERs), the expression and function of most GPCRs r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f707e8f16613b2296e9823e8de198b
http://hdl.handle.net/11588/776667
http://hdl.handle.net/11588/776667
Autor:
Kathleen A. Burke, Ian Waters, Agostina Nardone, Joe W. Gray, Martin Shea, Ben Ho Park, Carmine De Angelis, Sarmistha Nanda, Chandandeep Nagi, Daniel J. Zabransky, Mahitha Rajendran, Jamunarani Veeraraghavan, Felipe C Geyer, Tamika Mitchell, Carolina Gutierrez, Huizhong Hu, Gary C. Chamness, Britta Weigelt, C. Kent Osborne, Jorge S. Reis-Filho, Nicholas J. Wang, Vidyalakshmi Sethunath, Kenneth L. Scott, Rachel Schiff, Lanfang Qin, Xiaowei Xu, Alexander Renwick, Susan G. Hilsenbeck, Laura M. Heiser, Mothaffar F. Rimawi, Edward S. Chen, Chad A. Shaw, Charlotte K.Y. Ng, Tao Wang
Purpose: Resistance to anti-HER2 therapies in HER2+ breast cancer can occur through activation of alternative survival pathways or reactivation of the HER signaling network. Here we employed BT474 parental and treatment-resistant cell line models to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb068280b301594f2965d31acd31789
https://europepmc.org/articles/PMC5762201/
https://europepmc.org/articles/PMC5762201/
Autor:
Nrusingh C. Biswal, Sylvie Guichard, Agostina Nardone, Pavana Anur, Barry R. Davies, Martin Shea, Sabrina Herrera, Joe W. Gray, Mario Giuliano, Gladys Morrison, Rachel Schiff, Alejandro Contreras, Chad J. Creighton, Kristen L. Karlin, Susan G. Hilsenbeck, Thomas F. Westbrook, Sarmistha Nanda, Xiaoyong Fu, Carolina Gutierrez, Amit Joshi, Tao Wang, Adrian V. Lee, Paul T. Spellman, C. Kent Osborne, Gordon B. Mills, Vijetha Kumar, Mothaffar F. Rimawi, Teresa Klinowska, Laura M. Heiser, Paul D. Smith
Publikováno v:
Breast Cancer Research : BCR
Introduction Activation of the phosphatidylinositol 3-kinase (PI3K) pathway in estrogen receptor α (ER)-positive breast cancer is associated with reduced ER expression and activity, luminal B subtype, and poor outcome. Phosphatase and tensin homolog