Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yujie Huang"'
Autor:
Zhaorui Miao, Yuxin Zhou, Kai Zhao, Yang Yuan, Na Lu, Yujie Huang, Yang Hu, Libin Wei, Qinglong Guo
Publikováno v:
Oncotarget
// Yujie Huang 1 , Zhaorui Miao 1 , Yang Hu 1 , Yang Yuan 1 , Yuxin Zhou 1 , Libin Wei 1 , Kai Zhao 1 , Qinglong Guo 1 , Na Lu 1 1 State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis and Intervention, Jiangsu Key Labor
Autor:
Xingwu Jiang, Ofer Reizes, Weiqiang Lu, Ruth Nussinov, Charis Eng, Qi Wang, Yuan Hou, Yujie Huang, Justin D. Lathia, Zihao Wang, Feixiong Cheng, Jiansong Fang
Publikováno v:
Cell Chem Biol
Summary Triple-negative breast cancer (TNBC) is an aggressive and heterogeneous disease that lacks clinically actionable genetic alterations that limit targeted therapies. Here we explore a systems pharmacology approach that integrates drug-target ne
Autor:
Yuxin Zhou, Lei Tao, Qinglong Guo, Qidong You, Teng An, Zhiyu Li, Baoan Chen, Yan Chen, Xiaoping Wang, Rong Fu, Zhao-Qiu Wu, Yujie Huang
Publikováno v:
Oncotarget
Angiogenesis is associated with the progression of multiple myeloma (MM). Wogonin is an active mono-flavonoid with remarkable antitumor activity. However, its impact on MM-stimulated angiogenesis remains largely unknown. Here, we demonstrated that wo
Autor:
Zhiyu Li, Yuxin Zhou, Kai Zhao, Yang Hu, Qidong You, Xiaorui Li, Xuwei Luo, Qinglong Guo, Na Lu, Yujie Huang, Libin Wei
Publikováno v:
Molecular Carcinogenesis. 55:1598-1612
Wogonoside, a main flavonoid component derived from the root of Scutellaria baicalensis Georgi, has been reported to have anti-angiogenesis and anti-leukemia activities. However, whether it can inhibit tumor angiogenesis is unclear. In this study, we
Autor:
Yuan Gao, Qinglong Guo, Na Lu, Yulin Wu, Ruichen Guo, Yujie Huang, Zhiyu Li, Kai Zhao, Yuxin Zhou
Publikováno v:
RSC Adv.. 4:64565-64576
Excessive or inappropriate angiogenesis occurs in the pathogenesis process of many diseases, such as cancer, wound healing and eye disease, and angiogenesis stimulated by inflammatory factors particularly contributes to the development of inflammatio
Autor:
Zhiyu Li, Na Lu, Mi Zhou, Yujie Huang, Qinglong Guo, Jing Yao, Kai Zhao, Xiuming Song, Qidong You
Publikováno v:
European Journal of Pharmacology. 737:57-69
Wogonin has been shown to have anti-angiogenesis and anti-tumor effects. However, whether wogonin inhibits LPS-induced tumor angiogenesis is not well known. In this study, we investigated the effect of wogonin on inhibiting LPS-induced tumor angiogen
Autor:
Yujie Huang, Xiaomin Song, Yan Fu, Ling Li, Xiaofeng Wang, Shaopeng Yuan, Nan Song, Hubing Shi, Yongzhang Luo
Publikováno v:
The FASEB Journal. 22:2809-2820
Endostatin (ES) was reported to stimulate apoptosis in endothelial cells, but the exact mechanism remains controversial. In the present study, we elucidate the mechanism of ES-induced endothelial cell apoptosis. Our results indicate that ES induces c
Publikováno v:
Blood. 110:2899-2906
The exact molecular mechanism of how endostatin inhibits angiogenesis and tumor growth remains uncharacterized. Here, we report that endostatin specifically binds to the cell surface nucleolin with high affinity. Blockage of nucleolin by a neutralizi
Publikováno v:
Blood. 107:3564-3571
Nucleolin, originally described as a nuclear protein, was recently found to be expressed on the surface of endothelial cells during angiogenic. However, the functions of cell-surface nucleolin in angiogenic remain mysterious. Here we report that upon
Publikováno v:
Vascular pharmacology. 60(3)
Wogonin, a natural monoflavonoid extracted from Scutellariae radix, has been reported for its ability of inhibiting tumor angiogenesis. In this study, we assessed the effect of wogonin on angiogenesis induced by low level of H2O2 (10 μM) in human um