Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Winfred C Wang"'
Autor:
Scott T. Miller, Rathi V. Iyer, Russell E. Ware, Zora R. Rogers, Bea Files, Barry L. Shulkin, John H. Miller, Eglal Shalaby-Rana, Winfred C. Wang, Bruce W. Thompson, Zhaoyu Luo, Peter A. Lane, Stephen D. Dertinger
Publikováno v:
Blood. 117:2614-2617
We evaluated spleen function in 193 children with sickle cell anemia 8 to 18 months of age by 99mTc sulfur-colloid liver-spleen scan and correlated results with clinical and laboratory parameters, including 2 splenic biomarkers: pitted cell counts (P
Autor:
Tally Hustace, MaryLou MacDermott, Brenda Martin, Scott T. Miller, Zhaoyu Luo, Betsy Rackoff, Lea Adix, Billie Fish, Lynn W. Wynn, Phillip Seaman, Lane G. Faughnan, Tracy Kelly, Glenda Thomas, Caroline Reed, Jennifer McDuffie, Ellen Debenham, Joan Marasciulo, Mary A. Murphy, Winfred C. Wang
Publikováno v:
Contemporary Clinical Trials. 31:558-563
Background Protocol-eligible subjects may not be candidates for research participation or may decline. To determine factors that affected accrual, we evaluated enrollment in BABY HUG, a multi-center, randomized, placebo-controlled Phase III trial of
Autor:
William Schaffner, Natasha B. Halasa, Sadhna M. Shankar, Allen S. Craig, Patrick G. Arbogast, Marie R. Griffin, Winfred C. Wang, Ed Mitchel, Thomas R. Talbot
Publikováno v:
Clinical Infectious Diseases. 44:1428-1433
Background. We sought to determine the incidence of invasive pneumococcal disease (IPD) among individuals with sickle cell disease (SCD) before and after the introduction of the pneumococcal conjugate vaccine (PCV).Methods. Individuals with SCD who w
Autor:
Winfred C. Wang, Deepika Darbari, Samir K. Ballas, Meredith Milet, Nancy F. Olivieri, Kim Smith-Whitley, Paul Harmatz, Ellen B. Fung, Ward Hagar, William Owen, Elliott Vichinsky, Laura M. De Castro
Publikováno v:
American Journal of Hematology. 82:255-265
A natural history study was conducted in 142 Thalassemic (Thal), 199 transfused Sickle Cell Disease (Tx-SCD, n = 199), and 64 non-Tx-SCD subjects to describe the frequency of iron-related morbidity and mortality. Subjects recruited from 31 centers in
Autor:
Winfred C. Wang, Donald Brambilla, Nancy F. Olivieri, Lori Styles, Knashawn H. Morales, Robert J. Adams, Charles D. Scher
Publikováno v:
The Journal of Pediatrics. 147:244-247
Objective To determine whether long-term transfusion improves growth in children with sickle cell anemia. Study design In the Stroke Prevention Trial for Sickle Cell Anemia Study, patients were randomized to receive long-term transfusion (CTX) or sta
Autor:
Rupa Redding-Lallinger, Kwaku Ohene-Frempong, Lori Styles, Henry Lynn, Myron A. Waclawiw, Beatrice E. Gee, Ronald W. Helms, Elliott Vichinsky, Russell E. Ware, Kim Smith-Whitley, Winfred C. Wang, Thomas R. Kinney
Publikováno v:
The Journal of Pediatrics. 140:225-229
Objectives: Although hydroxyurea is effective in treating adults with sickle-cell anemia (SCA), there is concern that it may adversely affect growth in children. We report the growth characteristics of patients in the Phase I-II pediatric hydroxyurea
Publikováno v:
The Journal of Pediatrics. 139:790-796
Objective: Hydroxyurea improves hematologic values and decreases vaso-occlusive complications in adults and children with sickle cell anemia (SCA), but has not been tested in infants before the onset of chronic organ dysfunction. We conducted a colla
Publikováno v:
Journal of Pediatric Hematology/Oncology. 23:112-116
Prophylactic penicillin is effective in preventing severe invasive pneumococcal infection in children with sickle cell disease. In some families, compliance has been problematic. The aims of this study were to monitor compliance and to assess the eff
Autor:
Charles H. Pegelow, Miguel R. Abboud, Donald Brambilla, Winfred C. Wang, Brian Berman, Robert J. Adams, Scott T. Miller, Nancy F. Olivieri, Elliott Vichinsky, Virgil McKie
Publikováno v:
The Journal of Pediatrics. 126:896-899
Objective: To determine the effect of a transfusion program on risk of stroke recurrence in children with sickle cell disease. Design: The clinical course and experience with transfusion therapy at eight centers were reviewed for subjects whose initi
Autor:
Winfred C. Wang
Publikováno v:
Current opinion in hematology. 14(3)
Purpose of review Stroke is one of the most devastating complications of sickle cell disease, but current research has led to improved understanding of its pathogenesis and to new approaches in the prevention of both primary and secondary stroke. Thi