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pro vyhledávání: '"Tarja Lamminen"'
Autor:
Michelle Welsh, Sari Mäkelä, Tomi Streng, Taija Saloniemi, Philippa T. K. Saunders, Tarja Lamminen, Matti Poutanen
Publikováno v:
Molecular and Cellular Endocrinology. 301:163-168
When present in excess amounts during fetal life, androgens can impair female development by inducing masculinization. On way to modify fetal steroid concentration is by altering the expression of hydroxysteroid (17beta) dehydrogenases (HSD17Bs). Hum
Autor:
Philippa T. K. Saunders, Tarja Lamminen, Kaisa Huhtinen, Harry Kujari, Michelle Welsh, Taija Saloniemi, Matti Poutanen
Publikováno v:
Molecular Endocrinology. 21:2627-2636
Hydroxysteroid (17beta) dehydrogenases (HSD17Bs) belong to the short-chain dehydrogenase/reductase family consisting of a diverse pool of enzymes with oxidoreductase activity. HSD17B enzymes catalyze the conversion between 17-keto and 17-hydroxy ster