Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sabine E. Hannema"'
Autor:
Naomi Weintrob, Birgit Köhler, Sabine E. Hannema, Paul Martin Holterhus, Justin H Davies, Martine Cools, Angela K Lucas-Herald, Anna Nordenström, Antonio Balsamo, Christa E. Flück, Gilvydas Verkauskas, Otilia Marginean, Annemarie A. Verrijn Stuart, Laura Audí, Guy T'Sjoen, Mona Ellaithi, Lloyd J.W. Tack, Ellen Maris, Nils Krone, S Faisal Ahmed, Kirsten B. Kluivers, Leendert H. J. Looijenga, Stefan Riedl, Amy B. Wisniewski, Violeta Iotova, Katja P. Wolffenbuttel, Olcay Evliyaoğlu
Publikováno v:
Hormone research in pædiatrics, 90(4), 236. S. Karger AG
Hormone Research in Paediatrics, 90, 236-246
Tack, L J W, Maris, E, Looijenga, L H J, Hannema, S E, Audi, L, Köhler, B, Holterhus, P M, Riedl, S, Wisniewski, A, Flück, C E, Davies, J H, T'Sjoen, G, Lucas-Herald, A K, Evliyaoglu, O, Krone, N, Iotova, V, Marginean, O, Balsamo, A, Verkauskas, G, Weintrob, N, Ellaithi, M, Nordenström, A, Verrijn Stuart, A, Kluivers, K B, Wolffenbuttel, K P, Ahmed, S F & Cools, M 2019, ' Management of gonads in adults with androgen insensitivity : An international survey ', Hormone Research in Paediatrics, vol. 90, no. 4, pp. 236-246 . https://doi.org/10.1159/000493645
Hormone Research in Paediatrics, 90, 4, pp. 236-246
Hormone Research in Paediatrics, 90(4), 236-246. Karger
Hormone Research in Paediatrics, 90(4), 236-246
Hormone Research in Paediatrics, 90, 236-246
Tack, L J W, Maris, E, Looijenga, L H J, Hannema, S E, Audi, L, Köhler, B, Holterhus, P M, Riedl, S, Wisniewski, A, Flück, C E, Davies, J H, T'Sjoen, G, Lucas-Herald, A K, Evliyaoglu, O, Krone, N, Iotova, V, Marginean, O, Balsamo, A, Verkauskas, G, Weintrob, N, Ellaithi, M, Nordenström, A, Verrijn Stuart, A, Kluivers, K B, Wolffenbuttel, K P, Ahmed, S F & Cools, M 2019, ' Management of gonads in adults with androgen insensitivity : An international survey ', Hormone Research in Paediatrics, vol. 90, no. 4, pp. 236-246 . https://doi.org/10.1159/000493645
Hormone Research in Paediatrics, 90, 4, pp. 236-246
Hormone Research in Paediatrics, 90(4), 236-246. Karger
Hormone Research in Paediatrics, 90(4), 236-246
Background: Complete and partial androgen insensitivity syndrome (CAIS, PAIS) are associated with an increased risk of gonadal germ cell cancer (GGCC). Recent guidelines recommend gonadectomy in women with CAIS in late adolescence. Nevertheless, many
Publikováno v:
Journal of Pediatric Urology, 13(5)
Journal of Pediatric Urology, 13(5), 498.e1-498.e6. Elsevier BV
Chaudhry, S, Tadokoro-Cuccaro, R, Hannema, S E, Acerini, C L & Hughes, I A 2017, ' Frequency of gonadal tumours in complete androgen insensitivity syndrome (CAIS) : A retrospective case-series analysis ', Journal of Pediatric Urology, vol. 13, no. 5, pp. 498.e1-498.e6 . https://doi.org/10.1016/j.jpurol.2017.02.013
Journal of Pediatric Urology, 13(5), 498.e1-498.e6. Elsevier BV
Chaudhry, S, Tadokoro-Cuccaro, R, Hannema, S E, Acerini, C L & Hughes, I A 2017, ' Frequency of gonadal tumours in complete androgen insensitivity syndrome (CAIS) : A retrospective case-series analysis ', Journal of Pediatric Urology, vol. 13, no. 5, pp. 498.e1-498.e6 . https://doi.org/10.1016/j.jpurol.2017.02.013
Background Complete androgen insensitivity syndrome (CAIS) is an X-linked recessive disorder of sex development (DSD) where affected individuals are phenotypically female, but have an XY karyotype and testes. The risk of gonadal tumour development in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b561d6a6402e18a9f4ed2448269d3725
https://hdl.handle.net/1887/95167
https://hdl.handle.net/1887/95167
Autor:
Sabine E. Hannema, Paul Martin Holterhus, Ralf Werner, Peter Wieacker, Jenny Schütt, Albrecht Röpke, Olaf Hiort
Publikováno v:
Journal of Steroid Biochemistry and Molecular Biology, 101(1), 1-10. Elsevier Limited
Werner, R, Schütt, J, Hannema, S, Röpke, A, Wieacker, P, Hiort, O & Holterhus, P M 2006, ' Androgen receptor gene mutations in androgen insensitivity syndrome cause distinct patterns of reduced activation of androgen-responsive promoter constructs ', Journal of Steroid Biochemistry and Molecular Biology, vol. 101, no. 1, pp. 1-10 . https://doi.org/10.1016/j.jsbmb.2006.06.016
Werner, R, Schütt, J, Hannema, S, Röpke, A, Wieacker, P, Hiort, O & Holterhus, P M 2006, ' Androgen receptor gene mutations in androgen insensitivity syndrome cause distinct patterns of reduced activation of androgen-responsive promoter constructs ', Journal of Steroid Biochemistry and Molecular Biology, vol. 101, no. 1, pp. 1-10 . https://doi.org/10.1016/j.jsbmb.2006.06.016
Assessment of quantitative impairment of reporter gene activation is an important strategy proving pathogenetic relevance of androgen receptor (AR)-gene mutations in androgen insensitivity syndrome (AIS). We hypothesized the additional existence of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::853d54ea46244e50107899e670b078bb
https://research.vumc.nl/en/publications/c374dabd-0c8f-4561-973c-b3338d517cd2
https://research.vumc.nl/en/publications/c374dabd-0c8f-4561-973c-b3338d517cd2
Autor:
Nicholas Coleman, Sabine E. Hannema, Ian Scott, E. Rajpert-De Meyts, Niels E. Skakkebæk, Ieuan A. Hughes
Publikováno v:
Hannema, S E, Scott, I S, Rajpert-De Meyts, E, Skakkebæk, N E, Coleman, N & Hughes, I A 2006, ' Testicular development in the complete androgen insensitivity syndrome ', Journal of Pathology, vol. 208, no. 4, pp. 518-527 . https://doi.org/10.1002/path.1890
Journal of Pathology, 208(4), 518-527. John Wiley and Sons Ltd
Journal of Pathology, 208(4), 518-527. John Wiley and Sons Ltd
The complete androgen insensitivity syndrome (CAIS), caused by mutations in the androgen receptor (AR) gene, is associated with abnormal testicular development and an increased risk of germ cell malignancy. Previous histological studies in CAIS have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d690b378b290b110970318a2ba2ed05
https://research.vumc.nl/en/publications/b1d2ddc1-37dd-4168-937c-0171c3c52643
https://research.vumc.nl/en/publications/b1d2ddc1-37dd-4168-937c-0171c3c52643
Autor:
Nicholas Coleman, John Hodapp, Sabine E. Hannema, Howard Martin, Ian Scott, Ieuan A. Hughes, John W.R. Schwabe
Publikováno v:
Hannema, S E, Scott, I S, Hodapp, J, Martin, H, Coleman, N, Schwabe, J W & Hughes, I A 2004, ' Residual activity of mutant androgen receptors explains wolffian duct development in the complete androgen insensitivity syndrome ', Journal of Clinical Endocrinology and Metabolism, vol. 89, no. 11, pp. 5815-5822 . https://doi.org/10.1210/jc.2004-0709
Journal of Clinical Endocrinology and Metabolism, 89(11), 5815-5822. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 89(11), 5815-5822. The Endocrine Society
Development of the Wolffian ducts (WD) into epididymides and vasa deferentia is dependent on testosterone. Patients with the complete androgen insensitivity syndrome (CAIS) are therefore not expected to develop these structures. However, WD derivativ