Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Qiao-Qiao Li"'
Publikováno v:
Journal of Analytical Methods in Chemistry, Vol 2018 (2018)
Thrombin plays a vital role in blood coagulation, which is a key process involved in thrombosis by promoting platelet aggregation and converting fibrinogen to form the fibrin clot. In the receptor concept, drugs produce their therapeutic effects via
Externí odkaz:
https://doaj.org/article/becff11da8194a4e84ccdb0f72465681
Autor:
Ya-Li Wang, Guang Hu, Qian Zhang, Yu-Xiu Yang, Qiao-Qiao Li, Yuan-Jia Hu, Hua Chen, Feng-Qing Yang
Publikováno v:
Journal of Analytical Methods in Chemistry, Vol 2018 (2018)
Tyrosinase (TYR) is a rate-limiting enzyme in the synthesis of melanin, while direct TYR inhibitors are a class of important clinical antimelanoma drugs. This study established a spectrum-effect relationship analysis method and high-performance liqui
Externí odkaz:
https://doaj.org/article/4f11025ed27d471da110224e565ea896
Publikováno v:
Chromatographia. 81:509-516
Capillary electrophoresis (CE) has been widely used in the study of the interactions between targets (biological macromolecules) and ligands due to its good biocompatibility. However, the separation and analysis of platelets, which play a pivotal rol
Autor:
Zhining Xia, Yin-Zhen Wang, Yuanjia Hu, Peng Li, Jian-Bo Wan, Feng-Qing Yang, Qian Zhang, Qiao-Qiao Li, Feng-Qin Wang
Publikováno v:
Chromatographia. 80:341-345
In this study, a new capillary electrophoresis (CE) method was developed for the online determination of platelet aggregation induced by thrombin (THR). The developed CE method was applied to evaluate the anti-platelet aggregation activity of Rhizoma
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
A capillary electrophoresis (CE)-based beta-glucosidase (beta-Glu) immobilized enzyme microreactor (IMER) was constructed for enzyme kinetics study and inhibitor screening with the aid of polydopamine coating. The enzyme kinetic and inhibition studie
Publikováno v:
Journal of chromatography. A. 1570
The passive membrane permeability of drugs may be potentially predicted by phospholipid-water sorption coefficient (KPLIPW) through immobilized artificial membrane (IAM) chromatography. However, for predominantly ionized compounds, unexpected confoun
Publikováno v:
Talanta. 185
An online capillary electrophoresis (CE)-based thrombin (THR) immobilized enzyme microreactor (IMER) method was established to screen THR inhibitors in this study. S-2366 was used as chromogenic substrate for determination of THR activity and other k
Publikováno v:
Journal of Analytical Methods in Chemistry
Journal of Analytical Methods in Chemistry, Vol 2018 (2018)
Journal of Analytical Methods in Chemistry, Vol 2018 (2018)
Thrombin plays a vital role in blood coagulation, which is a key process involved in thrombosis by promoting platelet aggregation and converting fibrinogen to form the fibrin clot. In the receptor concept, drugs produce their therapeutic effects via
Autor:
Hua Chen, Yuanjia Hu, Guang Hu, Feng-Qing Yang, Ya-Li Wang, Qiao-Qiao Li, Qian Zhang, Yu-Xiu Yang
Publikováno v:
Journal of Analytical Methods in Chemistry
Journal of Analytical Methods in Chemistry, Vol 2018 (2018)
Journal of Analytical Methods in Chemistry, Vol 2018 (2018)
Tyrosinase (TYR) is a rate-limiting enzyme in the synthesis of melanin, while direct TYR inhibitors are a class of important clinical antimelanoma drugs. This study established a spectrum-effect relationship analysis method and high-performance liqui
Autor:
Yin-Zhen Wang, Yuanjia Hu, Feng-Qin Wang, Qiao-Qiao Li, Zhining Xia, Jian-Bo Wan, Peng Li, Feng-Qing Yang, Qian Zhang
Publikováno v:
Electrophoresis. 38(6)
In this study, the affinity interactions between RAW 264.7 macrophages and three small molecules include naringin, oleuropein and paeoniflorin were evaluated by affinity capillary electrophoresis (ACE), partial filling affinity capillary electrophore