Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ranise A."'
Autor:
Milena Chiavarini, Francesco Bondavalli, Angelo Ranise, Elisabetta Barocelli, Vigilio Ballabeni, Mariannina Impicciatore, Silvia Schenone, Simona Bertoni, Massimiliano Tognolini, Olga Bruno
Publikováno v:
Bioorganic & Medicinal Chemistry. 9:629-636
The preparation and the pharmacological screening of novel anti-aggregatory/antiphlogistic polycyclic pyrimidine derivatives are described. The compounds were developed starting from bioactive 2-aminobenzopyranopyrimidine derivatives in order to asse
Autor:
Giuseppe Falcone, Olga Bruno, Barbara Rinaldi, Walter Filippelli, Chiara Brullo, Angelo Ranise, Annalisa Capuano, Silvia Schenone, Francesco Bondavalli
Two series of N-[5-oxo-4-(arylsulfonyl)-4,5-dihydro-1,3,4-thiadiazol-2-yl]-amides were synthesized and tested in vivo for their analgesic and anti-inflammatory activities. All the new compounds possess good antalgic action in the acetic acid writhing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca2556d39a62a8101718c6731d06fbf
http://hdl.handle.net/11567/263243
http://hdl.handle.net/11567/263243
Autor:
Silvia Schenone, Francesco Bondavalli, Walter Filippelli, Filomena Mazzeo, Paola Fossa, Giuseppe Falcone, Luisa Mosti, Andrea Spallarossa, Angelo Ranise, Olga Bruno, Annalisa Capuano, Giulia Menozzi
Three series of N-acyl and N-cyclohexyl- or N-methyl or N-phenyl-thioureas of 4-substituted (methyl, phenyl, 2-pyridyl)piperazines (4-12) were synthesised according to a highly convergent one-pot procedure and tested in vivo (local anaesthetic, anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a279d604ebe2f03c9ac59e8b7ceabb45
http://hdl.handle.net/11367/644
http://hdl.handle.net/11367/644
Autor:
C. Brullo, Olga Bruno, Francesco Bondavalli, Silvia Schenone, Massimiliano Tognolini, Vigilio Ballabeni, Elisabetta Barocelli, Angelo Ranise
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 3(2)
New series of 5-alkoxy-benzopyranopyrimidine derivatives were developed from the chemical modulation of the substituent in position 2 of the scaffold, with the aim to produce analgesic/antiphlogistic agents more potent than analogues previously repor
Autor:
Schenone, S., Bruno, O., Ranise, A., Bondavalli, F., michele d'amico, Filippelli, W., Falcone, G., Novellis, V.
Publikováno v:
Scopus-Elsevier
The synthesis of novel 2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles 4a-f, starting from N-phenyl-3,4-dihydro-1(2H)-oxonaphthalene-2-carbothioamide and the proper arylhydrazines, is described. Title compounds were evaluated for antiinflammator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8b97ad0dbc814c946a5c8be613c07e24
http://hdl.handle.net/11591/203440
http://hdl.handle.net/11591/203440
Autor:
SCHENONE S, BRUNO O, RANISE A, BONDAVALLI F, VACCA C, FALCIANI M, FILIPPELLI A., D'AMICO, Michele
Publikováno v:
Farmaco (Societa chimica italiana : 1989). 49(9)
The synthesis of (+)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one O-[omega-(dialkylamino)alkyl]oximes by reaction of (+)-camphoroxime sodium salt with a series of omega-(chloroalkyl)dialkylamines in DMF solution is described. Some of the above compounds
Autor:
Bruno, O., Ranise, A., Bondavalli, F., Schenone, S., michele d'amico, Falciani, M., Vacca, C., Filippelli, A.
Publikováno v:
Scopus-Elsevier
The synthesis of 4-amino-3,5-diphenyl-1H-pyrazole-1-ethanol, as well as of their N-methyl, N-ethyl and N,N-dimethyl derivatives is described. A series of 1-(2-alkylaminoethyl)-3,5-diphenyl-1H-pyrazole-4-amines and of N-substituted 4-dimethylamino-3,5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::300249477dd983daacf2d42e7a53c7ac
http://hdl.handle.net/11386/3127952
http://hdl.handle.net/11386/3127952
Autor:
Vigilio Ballabeni, Massimiliano Tognolini, Francesco Bondavalli, Elisabetta Barocelli, Silvia Schenone, Olga Bruno, Chiara Brullo, Angelo Ranise
Publikováno v:
Bioorganicmedicinal chemistry. 12(3)
Synthesis and pharmacological screening of new 2-methylthio/2-methanesulfonyl/2-methoxy-5H-[1]benzopyrano[4,3-d]pyrimidines were planned in order to study the effects of the 5-substitution with alkoxy/phenoxy/alkylthio and phenylthio groups both on i
Autor:
Filomena Mazzeo, Annalisa Capuano, Walter Filippelli, Silvia Schenone, Giuseppe Falcone, Chiara Brullo, Olga Bruno, Francesco Bondavalli, Angelo Ranise
A series of 2-aryl-3-phenylamino-4,5-dihydro-2H-benz[g]indazoles was synthesized and tested for antiarrhythmic, local anaesthetic and analgesic activity. The title compounds showed a good antinociceptive activity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f9478c9c630678be55ebaeaf22f32a5
http://hdl.handle.net/11367/649
http://hdl.handle.net/11367/649
Autor:
Schenone, S., Bruno, O., Ranise, A., Bondavalli, F., michele d'amico, Parrillo, C., Lampa, E., Rossi, F.
Publikováno v:
Scopus-Elsevier
The synthesis of a series of N-substituted O-(3-amino-2-hydroxypropyl)oximes of 1,3,3-trimethyl-5-endo-(1-piperidinyl or 4-morpholinyl)-2-oxabicyclo [2.2.2]octan-6-ones is described. Some of these ethers showed strong local anesthetic activity in mic