Zobrazeno 1 - 2
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pro vyhledávání: '"Claudia Kathe"'
Autor:
Pietro Fratta, Jean-Marc Gallo, Boris Rogelj, Claire Troakes, Zupunski, Agnes L. Nishimura, Tibor Hortobágyi, Christopher Shaw, Michael Howell, Claudia Kathe
Publikováno v:
Brain. 133:1763-1771
Trans-activation response DNA-binding protein (TDP-43) accumulation is the major component of ubiquitinated protein inclusions found in patients with amyotrophic lateral sclerosis, and frontotemporal lobar degeneration with TDP-43 positive ubiquitina
Autor:
Emma L. Scotter, Agnes L. Nishimura, Mike Dragunow, Caroline Vance, Hazel Urwin, Boris Rogelj, Tibor Hortobágyi, Christopher Shaw, Christopher C.J. Miller, Claire Troakes, Claudia Kathe, Catherine Manser, Jacqueline C. Mitchell
Publikováno v:
Human Molecular Genetics
Mutations in the gene encoding Fused in Sarcoma (FUS) cause amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disorder. FUS is a predominantly nuclear DNA- and RNA-binding protein that is involved in RNA processing. Large FUS-immunoreact