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pro vyhledávání: '"Jonathan L.C. Lee"'
Publikováno v:
Psychopharmacology
Rationale Pharmacological targeting of memory reconsolidation is a promising therapeutic strategy for the treatment of fear memory-related disorders. However, the success of reconsolidation-based approaches depends upon the effective destabilisation
Publikováno v:
Frontiers in Behavioral Neuroscience
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Reconsolidation normally functions to update and maintain memories in the long-term. However, this process can be disrupted pharmacologically to weaken memories. Exploiting such experimental amnesia to disrupt the maladaptive reward memories underpin
Autor:
Jonathan L.C. Lee, Barry J. Everitt
Publikováno v:
Learning & Memory. 15:597-602
The theory of memory reconsolidation relates to the hypothesized restabilisation process that occurs following the reactivation of a memory through retrieval. Thus the demonstration of reactivation-dependent amnesia for a previously acquired memory i
Autor:
Jonathan L.C. Lee, Barry J. Everitt
Publikováno v:
Learning & Memory. 15:390-393
Previously acquired aversive and appetitive memories are not stable and permanent. The reactivation of such memories by re-exposure to training stimuli renders them vulnerable to disruption by amnestic agents such as the noncompetitive N-methyl-D-asp
Autor:
Jonathan L.C. Lee
Publikováno v:
Nature neuroscience. 11(11)
Memories are dynamic, rather than static, in nature. The reactivation of a memory through re-exposure to salient training stimuli results in its destabilization, necessitating a restabilization process known as reconsolidation, a disruption of which
Autor:
Jonathan L.C. Lee, Barry J. Everitt
Publikováno v:
Memories: Molecules and Circuits ISBN: 9783540456988
The persistence of memories reflects a dynamic, rather than a stable, process. The reactivation of a previously learned memory, for example by re-exposure to a conditioned stimulus, renders it labile, such that the concomitant administration of a var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdb66f44c40e2ce243fe93912ae5d34f
https://doi.org/10.1007/978-3-540-45702-2_6
https://doi.org/10.1007/978-3-540-45702-2_6
Publikováno v:
Science (New York, N.Y.). 304(5672)
The idea that new memories undergo a time-dependent consolidation process after acquisition has received considerable experimental support. More controversial has been the demonstration that established memories, once recalled, become labile and sens