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pro vyhledávání: '"Carmen Garnacho"'
Autor:
Carmen Garnacho, Silvia Muro
Publikováno v:
Journal of Drug Targeting. 25:786-795
Enzyme replacement is a viable treatment for diseases caused by genetic deficiency of lysosomal enzymes. However, suboptimal access of enzymes to target sites limits this strategy. Polymer nanocarriers (NCs) coated with antibody against intercellular
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 340:638-647
Intercellular adhesion molecule-1 (ICAM-1), a transmembrane glycoprotein expressed on activated endothelium and many other cells, represents a suitable target for delivery of drug nanocarriers (NCs) to disease areas. Numerous works have shown efficie