Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Dolph L. Hatfield"'
Autor:
Qiao Lu, Dolph L. Hatfield, Ji-Woon Na, Jin-Hong Kim, Byeong Jae Lee, Vadim N. Gladyshev, Jisu Jung, Bradley A. Carlson, Xiong Guo, Jeyoung Bang
Publikováno v:
Free radical biologymedicine. 127
Selenophosphate synthetase (SEPHS) synthesizes selenophosphate, the active selenium donor, using ATP and selenide as substrates. SEPHS was initially identified and isolated from bacteria and has been characterized in many eukaryotes and archaea. Two
Publikováno v:
Selenium ISBN: 9783319412818
A distinct feature of selenocysteine (Sec) biosynthesis is that this amino acid is synthesized on its tRNA, designated tRNA[Ser]Sec. Sec is then inserted into protein in response to the codon, UGA, as the 21st proteinogenic amino acid. In eukaryotes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a77804743aac1d04b76ef220116e31f8
https://doi.org/10.1007/978-3-319-41283-2_4
https://doi.org/10.1007/978-3-319-41283-2_4
Autor:
Dolph L. Hatfield, Min-Hyuk Yoo, Bradley A. Carlson, Anton A. Turanov, Vadim N. Gladyshev, Xue-Ming Xu
Publikováno v:
Advances in Nutrition. 2:122-128
The biosynthetic pathway for selenocysteine (Sec), the 21st amino acid in the genetic code whose codeword is UGA, was recently determined in eukaryotes and archaea. Sec tRNA, designated tRNA([Ser]Sec), is initially aminoacylated with serine by seryl-
Autor:
Dolph L. Hatfield, Yan Zhang, Valentina A. Shchedrina, Vyacheslav M. Labunskyy, Vadim N. Gladyshev
Publikováno v:
Antioxidants & Redox Signaling. 12:839-849
Selenium is an essential trace element in mammals. The major biological form of this micronutrient is the amino acid selenocysteine, which is present in the active sites of selenoenzymes. Seven of 25 mammalian selenoproteins have been identified as r
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1790:1424-1428
Selenium is an essential trace element for which both beneficial and toxic effects in human health have been described. It is now clear that the importance of having adequate amounts of this micronutrient in the diet is primarily due to the fact that
Publikováno v:
Molecules, Vol 14, Iss 9, Pp 3509-3527 (2009)
Selenium (Se) deficiency has been known for many years to be associated with disease, impaired growth and a variety of other metabolic disorders in mammals. Only recently has the major role that Se-containing proteins, designated selenoproteins, play
Autor:
Heiko Mix, Sherida Johnson, Jürgen Gailer, Chethaka Kahakachchi, Marla J. Berry, Kazima Saira, Neil E. Jacobsen, Peter C. Uden, Graham N. George, Richard S. Glass, Raghav Yamdagni, Ingrid J. Pickering, Qiao Wu, Shawn A. Manley, Eric Block, Harriet Totoe Boakye, Rafał Kamiński, Bradley A. Carlson, Elmar J. Prenner, Xue-Ming Xu, Dolph L. Hatfield, Vadim N. Gladyshev, Julian F. Tyson, Aleksandra Skowrońska, Yan Zhang
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 183:924-930
The long-sought pathway by which selenocysteyl-tRNA[Ser]Sec is synthesized in eukaryotes has been revealed. Seryl-tRNA[Ser]Sec is O-phosphorylated and SecS, a pyridoxal phosphate-dependent protein, catalyzes the reaction of O-phosphoseryl-tRNA[Ser]Se
Publikováno v:
Protein Science. 17:176-182
Proteins containing the 21st amino acid, selenocysteine (Sec), have been described in all three domains of life, but the composition of selenoproteomes in organisms varies significantly. Here, we report that aquatic arthropods possess many selenoprot
Autor:
Gregory V. Kryukov, Francisco Javier Martin-Romero, Dolph L. Hatfield, Boyoon Lee, Alexey V. Lobanov, Bradley A. Carlson, Vadim N. Gladyshev
Publikováno v:
Journal of Biological Chemistry. 276:29798-29804
Selenocysteine is a rare amino acid in protein that is encoded by UGA with the requirement of a downstream mRNA stem-loop structure, the selenocysteine insertion sequence element. To detect selenoproteins in Drosophila, the entire genome was analyzed
Autor:
M. A. El-Saadani, Gerald F. Combs, Byeong Jae Lee, Lionel Feigenbaum, Vadim N. Gladyshev, Qi An Sun, Raymond F. Burk, John W. Harney, Marla J. Berry, Dolph L. Hatfield, Mohamed E. Moustafa, Kristina E. Hill, Gregory V. Kryukov, Alan M. Diamond, Bradley A. Carlson, David B. Mansur
Publikováno v:
Molecular and Cellular Biology. 21:3840-3852
Selenocysteine (Sec) tRNA (tRNA([Ser]Sec)) serves as both the site of Sec biosynthesis and the adapter molecule for donation of this amino acid to protein. The consequences on selenoprotein biosynthesis of overexpressing either the wild type or a mut