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pro vyhledávání: '"Volpicelli, A."'
Akademický článek
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Publikováno v:
Neurobiology of Disease, Vol 124, Iss , Pp 248-262 (2019)
We recently identified a truncated and phosphorylated form of α-synuclein, pα-syn*, as a key neurotoxic α-synuclein species found in cultured neurons, as well as in mouse and Parkinson's disease patients' brains. Small pα-syn* aggregates localize
Externí odkaz:
https://doaj.org/article/86b28ea806a14f0397ab5a48f22af994
Autor:
Grassi, Diego, Howard, Shannon, Zhou, Minghai, Diaz-Perez, Natalia, Urban, Nicolai T., Guerrero-Given, Debbie, Kamasawa, Naomi, Volpicelli-Daley, Laura A., LoGrasso, Philip, Lasmézas, Corinne Ida
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2018 Mar . 115(11), E2634-E2643.
Externí odkaz:
https://www.jstor.org/stable/26508364
Autor:
Lindsay E. Stoyka, Andrew E. Arrant, Drake R. Thrasher, Dreson L. Russell, Jennifer Freire, Casey L. Mahoney, Ashwin Narayanan, Aseel G. Dib, David G. Standaert, Laura A. Volpicelli-Daley
Publikováno v:
Neurobiology of Disease, Vol 134, Iss , Pp - (2020)
Parkinson's disease (PD) is defined by motor symptoms such as tremor at rest, bradykinesia, postural instability, and stiffness. In addition to the classical motor defects that define PD, up to 80% of patients experience cognitive changes and psychia
Externí odkaz:
https://doaj.org/article/9833562d2ac34b90abc212b46135599b
Autor:
Orla O'Sullivan, Lorraine A. Draper, Sarah M. O’Donovan, Wiley Barton, Aideen M. Sullivan, Laura A. Volpicelli-Daley, Colin Hill, Stephen R. Stockdale, Catherine A. O'Neill
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Communications Biology
Communications Biology
Parkinson’s disease (PD) is a chronic neurological disorder associated with the misfolding of alpha-synuclein (α-syn) into aggregates within nerve cells that contribute to their neurodegeneration. Recent evidence suggests α-syn aggregation may be
Autor:
Enquan Xu, Ravindra Boddu, Hisham A. Abdelmotilib, Arpine Sokratian, Kaela Kelly, Zhiyong Liu, Nicole Bryant, Sidhanth Chandra, Samantha M. Carlisle, Elliot J. Lefkowitz, Ashley S. Harms, Etty N. Benveniste, Talene A. Yacoubian, Laura A. Volpicelli-Daley, David G. Standaert, Andrew B. West
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-19 (2022)
Molecular Neurodegeneration
Molecular Neurodegeneration
Background Leucine rich repeat kinase 2 (LRRK2) and SNCA are genetically linked to late-onset Parkinson’s disease (PD). Aggregated α-synuclein pathologically defines PD. Recent studies identified elevated LRRK2 expression in pro-inflammatory CD16+
Autor:
Mahoney-Crane, Casey L., Viswanathan, Megha, Russell, Dreson, Curtiss, Rachel A. C., Freire, Jennifer, Bobba, Sai Sumedha, Coyle, Sean D., Kandebo, Monika, Lihang Yao, Bang-Lin Wan, Hatcher, Nathan G., Smith, Sean M., Marcus, Jacob N., Volpicelli-Daley, Laura A.
Publikováno v:
Journal of Neuroscience; 1/18/2023, Vol. 43 Issue 3, p501-521, 21p
Autor:
Nadia M. Anabtawi, Nunilo Cremades, Janet R. Kumita, Christopher M. Dobson, Serene W. Chen, José D. Camino, Marta Castellana-Cruz, Laura A. Volpicelli-Daley, Allen A. Yazdi, Jennifer Freire, Sheila M. Fleming, Jessica M. Froula, Drake R. Thrasher
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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15 pags, 7 figs, 2 tabs
Parkinson's disease (PD) is a neurodegenerative disorder characterized by fibrillar neuronal inclusions composed of aggregated α-synuclein (α-syn). These inclusions are associated with behavioral and pathological PD phe
Parkinson's disease (PD) is a neurodegenerative disorder characterized by fibrillar neuronal inclusions composed of aggregated α-synuclein (α-syn). These inclusions are associated with behavioral and pathological PD phe
Autor:
Nolwazi Z. Gcwensa, Edward S. Boyden, Laura A. Volpicelli-Daley, Vijay Singh, Deblina Sarkar, Kaela Kelly, Andrew B. West, Baraa A. Hijaz, Charlotte F. Brzozowski
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-18 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Pathologic inclusions composed of α-synuclein called Lewy pathology are hallmarks of Parkinson’s Disease (PD). Dominant inherited mutations in leucine rich repeat kinase 2 (LRRK2) are the most common genetic cause of PD. Lewy pathology is found in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f83c404955d9677941eb3b5389dec1
https://doi.org/10.1101/2021.10.04.463043
https://doi.org/10.1101/2021.10.04.463043
Akademický článek
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