Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Erik Wambre"'
Autor:
Veronique Bajzik, Hannah A. DeBerg, Nahir Garabatos, Blake J. Rust, Kimberly K. Obrien, Quynh‐Anh Nguyen, Colin O’Rourke, Alex Smith, Alex H. Walker, Charlie Quinn, Vivian H. Gersuk, Mary Farrington, David Jeong, Brian P. Vickery, Daniel C. Adelman, Erik Wambre
Publikováno v:
Allergy. 77(8)
The PALISADE study, an international, phase 3 trial of peanut oral immunotherapy (POIT) with AR101, resulted in desensitization in children and adolescents who were highly allergic to peanut. An improved understanding of the immune mechanism induced
Autor:
Erik Wambre, David Jeong
Publikováno v:
Immunology and Allergy Clinics of North America. 38:27-37
The gastrointestinal tract has an abundant mucosal immune system to develop and maintain oral tolerance. The oral route of administration takes advantage of the unique set of immune cells and pathways involved in the induction of oral tolerance. Food
Publikováno v:
Journal of Allergy and Clinical Immunology. 141:491-498
Oral immunotherapy (OIT) has demonstrated reproducibly successful desensitization in patients with food allergy completing clinical trials and, in some studies, sustained unresponsiveness. These clinical outcomes have been associated with characteris
Autor:
Erik, Wambre
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2020
Understanding the mechanism underlying allergic disease is dependent upon definition of the heterogeneity and complexity of the cellular immune response toward allergens both in the context of disease and clinical intervention. Among all components o
Autor:
Erik Wambre, Blake J. Rust
Publikováno v:
Current Allergy and Asthma Reports. 17
Encouraging results from recent food allergen immunotherapy clinical trials indicate that the immune system plays an essential role in peripheral tolerance to food allergen. Thus, the monitoring of changes in immune responses and their possible corre
Autor:
Friedrich Horak, Philippe Moingeon, Véronique Baron-Bodo, A.-C. Rimaniol, C. Ricarte, Hélène Moussu, Erik Wambre, S. Horiot, William W. Kwok, M. Bonvalet, O. de Beaumont
Publikováno v:
Clinical & Experimental Allergy. 42:1745-1755
BACKGROUND Surrogate biomarkers of efficacy are needed in support of allergen-specific immunotherapy. OBJECTIVE The aim of this study was to relate changes in peripheral CD4(+) T cell responses to clinical efficacy during sublingual immunotherapy (SL
Autor:
Pandurangan Vijayanand, Eddie A. James, Jason A. Greenbaum, Amin Moghaddas Gholami, Veronique Schulten, Brandie White, Alessandro Sette, Erik Wambre, David H. Broide, Jerome Lane, William W. Kwok, Grégory Seumois, Carla Oseroff, John Sidney, Denise Hinz, Bjoern Peters, Pearl Bakhru
Background Timothy grass (TG) pollen is a common seasonal airborne allergen associated with symptoms ranging from mild rhinitis to severe asthma. Objective The aim of this study was to characterize changes in TG-specific T cell responses as a functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4536e9653db15f4f30694d07a94e224
https://europepmc.org/articles/PMC4846575/
https://europepmc.org/articles/PMC4846575/
Autor:
Mohamed H. Shamji, Stephen R. Durham, William W. Kwok, Tielin Qin, Guy W. Scadding, Kristina M. Harris, Stephen J. Till, Peter Adler Würtzen, Gerald T. Nepom, Amédée Renand, Alkis Togias, Erik Wambre
Publikováno v:
1760.e1
Renand, A, Shamji, M H, Harris, K M, Qin, T, Wambre, E, Scadding, G W, Wurtzen, P A, Till, S J, Togias, A, Nepom, G T, Kwok, W W & Durham, S R 2018, ' Synchronous Immune Alterations Mirror Clinical Response During Allergen Immunotherapy ', Journal of Allergy and Clinical Immunology, vol. 141, no. 5, pp. 1750-1760 . https://doi.org/10.1016/j.jaci.2017.09.041
Renand, A, Shamji, M H, Harris, K M, Qin, T, Wambre, E, Scadding, G W, Wurtzen, P A, Till, S J, Togias, A, Nepom, G T, Kwok, W W & Durham, S R 2018, ' Synchronous Immune Alterations Mirror Clinical Response During Allergen Immunotherapy ', Journal of Allergy and Clinical Immunology, vol. 141, no. 5, pp. 1750-1760 . https://doi.org/10.1016/j.jaci.2017.09.041
Background Three years of treatment with either sublingual or subcutaneous allergen immunotherapy has been shown to be effective and to induce long-term tolerance. The Gauging Response in Allergic Rhinitis to Sublingual and Subcutaneous Immunotherapy
Autor:
Erik Wambre, Robert Humphreys, Eric von Hofe, Didier G. Ebo, Bernard Maillere, Lydia Ferhat, Laurence Van Overtvelt, Philippe Moingeon
Publikováno v:
International archives of allergy and immunology
Background: We report herein critical methodological principles for assessing, at a single cell level, allergen-specific T cell responses using MHC class II peptide tetramers. Methods: We developed MHC class II peptide tetramers to monitor T cell res
Autor:
Erik, Wambre, Veronique, Bajzik, Jonathan H, DeLong, Kimberly, O'Brien, Quynh-Anh, Nguyen, Cate, Speake, Vivian H, Gersuk, Hannah A, DeBerg, Elizabeth, Whalen, Chester, Ni, Mary, Farrington, David, Jeong, David, Robinson, Peter S, Linsley, Brian P, Vickery, William W, Kwok
Publikováno v:
Science translational medicine. 9(401)
Allergen-specific type 2 helper T (TH2) cells play a central role in initiating and orchestrating the allergic and asthmatic inflammatory response pathways. One major factor limiting the use of such atopic disease–causing T cells as both therapeuti