Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Cristina Capittini"'
Publikováno v:
World Journal of Gastroenterology
BACKGROUND Celiac Disease (CD) is an immune-mediated disorder, in which the HLA immunogenetic background (DQ2 and DQ8 heterodimers) and environmental trigger (gluten) are well established. Indeed, both factors are necessary – but not sufficient –
Autor:
Carmine Tinelli, Miryam Martinetti, Cristina Capittini, A. De Silvestri, Giulia Mallucci, Chiara Rebuffi, Annamaria Pasi, Roberto Bergamaschi
Publikováno v:
Disease Markers, Vol 2019 (2019)
Disease Markers
Disease Markers
Multiple Sclerosis (MS) displays a heterogeneous clinical onset and progression, which are mostly unpredictable, but demyelination of the central nervous system (CNS) leads to substantial deficits of sensory, motor, autonomic, and neurocognitive func
Publikováno v:
International Journal of Immunogenetics. 46:342-345
Through a retrospective analysis of a real-life cohort of children with celiac disease (CD), who underwent HLA-DQ genotyping, we supported our previous findings indicating the presence of HLA-DQB1*02 allele in at least 90%-95% of pediatric patients.
Autor:
Carmine Tinelli, Chiara Valsecchi, Sara Carlotta Tagliacarne, Annalisa De Silvestri, Chiara Rebuffi, Miryam Martinetti, Valeria Scotti, Dimitri Poddighe, Gian Luigi Marseglia, Annamaria Pasi, Cristina Capittini
Publikováno v:
Pediatric Research. 83:564-572
BackgroundSpecific HLA-DQ genes have been recognized as necessary - but not sufficient - factors for the occurrence of Celiac Disease (CD). Through a meta-analysis, evaluating the distribution of CD-related HLA genotypes in children, we aimed at prov
Autor:
L. Mascaretti, Gian Luigi Marseglia, Valeria Scotti, Chiara Rebuffi, Dimitri Poddighe, Elena Bevilacqua, Carmine Tinelli, Miryam Martinetti, Annamaria Pasi, Annalisa De Silvestri, Cristina Capittini
Publikováno v:
Autoimmunity Reviews. 16:1230-1236
Juvenile Idiopathic Arthritis (JIA) is characterized with a variable pattern of articular involvement and systemic symptoms and, thus, it has been classified in several subtypes. Genetic predisposition to JIA is mainly due to HLA class II molecules (
Autor:
Annalisa De Silvestri, Francesco Messina, Sebastiana Toscano, Fabrizio Puglisi, Maria Azzaro, Cristina Capittini, Carmine Tinelli, Grazia Sortino
Publikováno v:
Human immunology. 79(1)
A geographical stratification of Killer Immunoglobulin-like Receptors (KIR) has been reported worldwide. We first analyzed the distribution of 15 KIR genes in a sample of 50 East-Sicilians (ES). We used a Principal Component Analysis (PCA) to compare
Autor:
Cesare Perotti, Annamaria Pasi, M. Guarene, Carmine Tinelli, A. De Silvestri, Cristina Capittini
Publikováno v:
Human immunology. 78(5-6)
Publikováno v:
Medicina, Vol 55, Iss 5, p 190 (2019)
Medicina
Medicina
Background and Objectives: Celiac disease (CD) is a multifactorial immune-mediated disorder, triggered by the ingestion of gluten in genetically-predisposed subjects carrying MHC-DQ2 and -DQ8 heterodimers, which are encoded by four HLA-DQ allelic var
Autor:
Ilaria Sbarsi, A. De Silvestri, Carmine Tinelli, M. Guarene, Miryam Martinetti, Mariaclara Cuccia, Laura Salvaneschi, C. Badulli, F. Garlaschelli, Annamaria Pasi, Paola Bergamaschi, M. P. Mercati, Cristina Capittini
Publikováno v:
Tissue Antigens. 74:156-163
Birth weight is known to be a direct indicator of perinatal mortality and a clear predictor of adult pathologies too. It has been correlated with several causes of mortality in adulthood: low birth weight with diabetes, nephropathy and cardiovascular
Autor:
Ilaria Sbarsi, C. Pizzochero, M. Martinetti, A. L. Cremaschi, Carmine Tinelli, F. Garlaschelli, Laura Salvaneschi, C. Badulli, Annamaria Pasi, C Monti, M. Guarene, Cristina Capittini
Publikováno v:
Genes and immunity. 13(6)
The HLA genomic structure underlines the permanence of fixed haplotypes transmitted in blocks as allelic combinations. One of the most discussed concerns is how and why such a strong linkage between HLA alleles has been maintained for so long. We hyp