Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Falk Kiefer"'
Autor:
Nadja Grundinger, Sarah Gerhardt, Damian Karl, Karl Mann, Falk Kiefer, Sabine Vollstädt-Klein
Publikováno v:
Psychopharmacology. 239:2471-2489
Rationale Central aspects of alcohol use disorder (AUD) are the irresistible desire for alcohol and impaired control over its intake. According to the triadic neurocognitive model of addiction, this arises from aberrant functioning of different neura
Autor:
Amadeus Magrabi, Anne Beck, Daniel J. Schad, Tristram A. Lett, Christian M. Stoppel, Katrin Charlet, Falk Kiefer, Andreas Heinz, Henrik Walter
Publikováno v:
Alcoholism: Clinical and Experimental Research. 46:749-758
Impaired decision making, a key characteristic of alcohol dependence (AD), manifests in continuous alcohol consumption despite severe negative consequences. The neural basis of this impairment in individuals with AD and differences with known neural
Autor:
Chiang-Shan R. Li, Sage Hahn, Robert Hester, Martin P. Paulus, Luijten Maartje, Valentina Lorenzetti, Catherine Orr, Kent Hutchinson, Nicholas Allgaier, Falk Kiefer, Henrik Walter, Patricia J. Conrod, Elliot A. Stein, Rajita Sinha, Scott Mackey, Dan J. Stein, Reinout W. Wiers, John J. Foxe, Edythe D. London, Murat Yücel, Tristram A. Lett, Dick J. Veltman, Andreas Heinz, Lianne Schmaal, Hugh Garavan, Janna Cousijn, Ruth J. van Holst, Ozlem Korucuoglu, Zsuzsika Sjoerds, Reza Momenan, Paul M. Thompson
Publikováno v:
Human brain mapping, vol 43, iss 1
Human Brain Mapping, 43, 1, pp. 555-565
Human Brain Mapping, 43(1), 555-565. Wiley-Liss Inc.
Human Brain Mapping
HUMAN BRAIN MAPPING
Hahn, S, Mackey, S, Cousijn, J, Foxe, J J, Heinz, A, Hester, R, Hutchinson, K, Kiefer, F, Korucuoglu, O, Lett, T, Li, C-S R, London, E, Lorenzetti, V, Maartje, L, Momenan, R, Orr, C, Paulus, M, Schmaal, L, Sinha, R, Sjoerds, Z, Stein, D J, Stein, E, van Holst, R J, Veltman, D, Walter, H, Wiers, R W, Yucel, M, Thompson, P M, Conrod, P, Allgaier, N & Garavan, H 2022, ' Predicting alcohol dependence from multi-site brain structural measures ', Human Brain Mapping, vol. 43, no. 1, pp. 555-565 . https://doi.org/10.1002/hbm.25248
Human brain mapping, 43(1), 555-565. Wiley-Liss Inc.
Human Brain Mapping, 43, 555-565
Human Brain Mapping, 43, 1, pp. 555-565
Human Brain Mapping, 43(1), 555-565. Wiley-Liss Inc.
Human Brain Mapping
HUMAN BRAIN MAPPING
Hahn, S, Mackey, S, Cousijn, J, Foxe, J J, Heinz, A, Hester, R, Hutchinson, K, Kiefer, F, Korucuoglu, O, Lett, T, Li, C-S R, London, E, Lorenzetti, V, Maartje, L, Momenan, R, Orr, C, Paulus, M, Schmaal, L, Sinha, R, Sjoerds, Z, Stein, D J, Stein, E, van Holst, R J, Veltman, D, Walter, H, Wiers, R W, Yucel, M, Thompson, P M, Conrod, P, Allgaier, N & Garavan, H 2022, ' Predicting alcohol dependence from multi-site brain structural measures ', Human Brain Mapping, vol. 43, no. 1, pp. 555-565 . https://doi.org/10.1002/hbm.25248
Human brain mapping, 43(1), 555-565. Wiley-Liss Inc.
Human Brain Mapping, 43, 555-565
To identify neuroimaging biomarkers of alcohol dependence (AD) from structural magnetic resonance imaging, it may be useful to develop classification models that are explicitly generalizable to unseen sites and populations. This problem was explored
Autor:
Christiane Mühle, Valery Grinevich, Johannes Kornhuber, Patrick Bach, Christian Weinland, Falk Kiefer, Bernd Lenz, Iulia Zoicas
Publikováno v:
European Neuropsychopharmacology. 51:55-67
Alcohol use disorder (AUD) is a severe illness, for which we lack sufficient mechanistic understanding. Preliminary evidence associates AUD with the oxytocin (OXT) system. Here we investigated alterations in endogenous OXT blood concentrations in pat
Autor:
Sarah Gerhardt, Oksana Berhe, Carolin Moessnang, Maibritt Horning, Falk Kiefer, Heike Tost, Sabine Vollstädt‐Klein
Publikováno v:
Addiction Biology. 28
Aberrant limbic circuit reactivity to negative stimuli might be related to alterations in emotion processing and regulation in alcohol use disorder (AUD). The current study tested for the first time in AUD the hypothesis of aberrant amygdala habituat
Autor:
Richard M. Weinshilboum, David Goldman, Jennifer R. Geske, Victor M. Karpyak, Sofia Pozsonyiova, Colin A. Hodgkinson, Lea Zillich, Ada Man-Choi Ho, Ray Anton, Colin L. Colby, Ming Fen Ho, Brandon J. Coombes, Anthony Batzler, Stephanie S. O'Malley, Josef Frank, Joanna M. Biernacka, M. Rietschel, Karl Mann, Falk Kiefer, Michelle K. Skime
Publikováno v:
Neuropsychopharmacology
Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit from these treatments. Here we present the first genome-wide association study of AUD treatme
Autor:
Lea Wetzel, Madeleine Pourbaix, Alisa Riegler, Anna-Maria Pfeifer, Iris Reinhard, Sabine Hoffmann, Sabine Vollstädt-Klein, Falk Kiefer, Wolfgang Sommer, Jan Malte Bumb, Patrick Bach, Anne Koopmann
Publikováno v:
Trials. 23(1)
Background Multiple studies indicate that a lower plasma level of the acetylated form of the appetite-regulating hormone ghrelin and higher plasma levels of insulin lead to a reduction in subjective alcohol craving and a reduced mesolimbic cue reacti
Autor:
Patrick Bach, Georg Weil, Sabine Vollstädt-Klein, Derik Hermann, Enrico Pompili, Karl Mann, Sabine Hoffmann, Wolfgang H. Sommer, Falk Kiefer
Publikováno v:
European Archives of Psychiatry and Clinical Neuroscience
Pharmacological treatment in alcohol use disorder suffers from modest effect sizes. Efforts have been undertaken to identify patient characteristics that help to select individuals that benefit from pharmacological treatment. Previous studies indicat
Autor:
Sabine Vollstädt-Klein, Àlvar Farré-Colomés, Mathias Luderer, Falk Kiefer, Sarah Gerhardt, Esther Sobanski
Publikováno v:
Alcoholism: Clinical and Experimental Research. 45:948-960
BACKGROUND: The relation between Attention Deficit/Hyperactivity Disorder (ADHD) and Alcohol Use Disorder (AUD) has been widely demonstrated. In this study, we aimed to investigate the connectivity traits that would help to understand the strong link
Autor:
Patrick Bach, Christina Dinter, Damian Karl, Karl Mann, Anne Koopmann, Falk Kiefer, Derik Hermann, Sabine Vollstädt-Klein, J. Malte Bumb
Publikováno v:
Psychopharmacology
Rationale Alcohol use disorder is a common and devastating mental illness for which satisfactory treatments are still lacking. Nalmefene, as an opioid receptor modulator, could pharmacologically support the reduction of drinking by reducing the (anti