Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Karch, Celeste M."'
Autor:
Schultz, Stephanie A., Shirzadi, Zahra, Schultz, Aaron P., Liu, Lei, Fitzpatrick, Colleen D., McDade, Eric, Barthelemy, Nicolas R., Renton, Alan, Esposito, Bianca, Joseph‐Mathurin, Nelly, Cruchaga, Carlos, Chen, Charles D., Goate, Alison, Allegri, Ricardo Francisco, Benzinger, Tammie L. S., Berman, Sarah, Chui, Helena C., Fagan, Anne M., Farlow, Martin R., Fox, Nick C., Gordon, Brian A., Day, Gregory S., Graff‐Radford, Neill R., Hassenstab, Jason J., Hanseeuw, Bernard, Hofmann, Anna, Jack, Clifford R., Jucker, Mathias, Karch, Celeste M., Koeppe, Robert A., Lee, Jae‐Hong, Levey, Allan I., Levin, Johannes, Martins, Ralph N., Mori, Hiroshi, Morris, John C., Noble, James, Perrin, Richard J., Rosa‐Neto, Pedro, Salloway, Stephen P., Sanchez‐Valle, Raquel, Schofield, Peter R., Xiong, Chengjie, Johnson, Keith A., Bateman, Randall J., Sperling, Reisa A., Chhatwal, Jasmeer P.
Publikováno v:
Aging Cell, (2023)
Although pathogenic variants in PSEN1 leading to autosomal-dominant Alzheimer disease (ADAD) are highly penetrant, substantial interindividual variability in the rates of cognitive decline and biomarker change are observed in ADAD. We hypothesized th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1493::dd59b7a44f93d682105c279d4eb1e6e1
https://hdl.handle.net/2078.1/275667
https://hdl.handle.net/2078.1/275667
Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease
Autor:
Dincer, Aylin, Gordon, Brian A, Allegri, Ricardo, Ances, Beau M, Berman, Sarah B, Brickman, Adam M, Brooks, William S, Cash, David M, Chhatwal, Jasmeer P, Farlow, Martin R, la Fougère, Christian, Fox, Nick C, Hari-Raj, Amrita, Fulham, Michael J, Jack, Clifford R, Joseph-Mathurin, Nelly, Karch, Celeste M, Lee, Athene, Levin, Johannes, Masters, Colin L, McDade, Eric M, Oh, Hwamee, Perrin, Richard J, Keefe, Sarah J, Raji, Cyrus, Salloway, Stephen P, Schofield, Peter R, Su, Yi, Villemagne, Victor L, Wang, Qing, Weiner, Michael W, Xiong, Chengjie, Yakushev, Igor, Morris, John C, Flores, Shaney, Bateman, Randall J, L S Benzinger, Tammie, DIAN, Dominantly Inherited Alzheimer Network, McKay, Nicole S, Paulick, Angela M, Shady Lewis, Kristine E, Feldman, Rebecca L, Hornbeck, Russ C
Publikováno v:
NeuroImage: Clinical 28, 102491-(2020). doi:10.1016/j.nicl.2020.102491
NeuroImage: Clinical, Vol 28, Iss, Pp 102491-(2020)
NeuroImage : Clinical
NeuroImage: Clinical, Vol 28, Iss, Pp 102491-(2020)
NeuroImage : Clinical
Highlights • Cortical signatures selective to AD could provide an early MRI biomarker. • Autosomal dominant Alzheimer disease (ADAD) may model an ideal AD signature. • ADAD and late-onset maps overlap in parietal cortex but contain unique featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2137b8c6fb5949e67aad2cd45279f38e
https://pub.dzne.de/record/154742
https://pub.dzne.de/record/154742
Autor:
Karch, Celeste M, Kao, Aimee W, Karydas, Anna, Onanuga, Khadijah, Martinez, Rita, Argouarch, Andrea, Wang, Chao, Huang, Cindy, Sohn, Peter Dongmin, Bowles, Kathryn R, Spina, Salvatore, Silva, M Catarina, Marsh, Jacob A, Hsu, Simon, Pugh, Derian A, Ghoshal, Nupur, Norton, Joanne, Huang, Yadong, Lee, Suzee E, Seeley, William W, Theofilas, Panagiotis, Grinberg, Lea T, Moreno, Fermin, McIlroy, Kathryn, Boeve, Bradley F, Cairns, Nigel J, Crary, John F, Haggarty, Stephen J, Ichida, Justin K, Kosik, Kenneth S, Miller, Bruce L, Gan, Li, Goate, Alison M, Temple, Sally, Tau Consortium Stem Cell Group
Publikováno v:
Stem cell reports, vol 13, iss 5
Primary tauopathies are characterized neuropathologically by inclusions containing abnormal forms of the microtubule-associated protein tau (MAPT) and clinically by diverse neuropsychiatric, cognitive, and motor impairments. Autosomal dominant mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::69cec0b5749f331cf52c5ba02705db07
https://escholarship.org/uc/item/3qq1v8t1
https://escholarship.org/uc/item/3qq1v8t1
Autor:
Dube, Umber, Del-Aguila, Jorge L, Li, Zeran, Budde, John P, Jiang, Shan, Hsu, Simon, Ibanez, Laura, Fernandez, Maria Victoria, Farias, Fabiana, Norton, Joanne, Gentsch, Jen, Wang, Fengxian, Dominantly Inherited Alzheimer Network (DIAN), Salloway, Stephen, Masters, Colin L, Lee, Jae-Hong, Graff-Radford, Neill R, Chhatwal, Jasmeer P, Bateman, Randall J, Morris, John C, Karch, Celeste M, Harari, Oscar, Cruchaga, Carlos
Publikováno v:
Nature neuroscience, vol 22, iss 11
Parietal cortex RNA-sequencing (RNA-seq) data were generated from individuals with and without Alzheimer disease (AD; ncontrol = 13; nAD = 83) from the Knight Alzheimer Disease Research Center (Knight ADRC). Using this and an independent (Mount Sinai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::76331cdeb7b9a88392aecde4c39d2b4a
https://escholarship.org/uc/item/0jm9274x
https://escholarship.org/uc/item/0jm9274x
Autor:
Bonham, Luke W, Karch, Celeste M, Ferrari, Raffaele, Danek, A., Van Deerlin, V. M., Grossman, M., Trojanowski, J. Q., van der Zee, J., Cruts, M., Van Broeckhoven, C., Cappa, S. F., Leber, I., Hannequin, D., Hardy, John, Golfier, V., Vercelletto, M., Brice, A., Nacmias, B., Sorbi, S., Bagnoli, S., Piaceri, I., Nielsen, J. E., Hjermind, L. E., Riemenschneider, M., Momeni, Parastoo, Mayhaus, M., Ibach, B., Gasparoni, G., Pichler, S., Gu, W., Rossor, M. N., Fox, N. C., Warren, J. D., Spillantini, M. G., Morris, H. R., Höglinger, Günter, Rizzu, P., Heutink, P., Snowden, J. S., Rollinson, S., Richardson, A., Gerhard, A., Bruni, A. C., Maletta, R., Frangipane, F., Cupidi, C., Müller, Ulrich, Bernardi, L., Anfossi, M., Gallo, M., Conidi, M. E., Smirne, N., Rademakers, R., Baker, M., Dickson, D. W., Graff-Radford, N. R., Petersen, R. C., Hess, Christopher P, Knopman, D., Josephs, K. A., Boeve, B. F., Parisi, J. E., Seeley, W. W., Miller, B. L., Karydas, A. M., Rosen, H., van Swieten, J. C., Dopper, E. G. P., Sugrue, Leo P, Seelaar, H., Pijnenburg, Y. A. L., Scheltens, P., Logroscino, G., Capozzo, R., Novelli, V., Puca, A. A., Franceschi, M., Postiglione, A., Milan, G., Dillon, William P, Sorrentino, P., Kristiansen, M., Chiang, H-H, Graff, C., Pasquier, F., Rollin, A., Deramecourt, V., Lebouvier, T., Kapogiannis, D., Ferrucci, L., Schellenberg, Gerard D, Pickering-Brown, S., Singleton, A. B., Hardy, J., Momeni, P., Miller, Bruce L, Fan, Chun C, Andreassen, Ole A, Dale, Anders M, Barkovich, A James, Yokoyama, Jennifer S, Desikan, Rahul S, Consortium, International FTD-Genomics, Consortium, International Parkinson’s Disease Genetics, Project, International Genomics of Alzheimer’s, Ferrari, R., Hernandez, D. G., Tan, Chin, Nalls, M. A., Rohrer, J. D., Ramasamy, A., Kwok, J. B. J., Dobson-Stone, C., Schofield, P. R., Halliday, G. M., Hodges, J. R., Piguet, O., Bartley, L., Geier, Ethan G, Thompson, E., Haan, E., Hernández, I., Ruiz, A., Boada, M., Borroni, B., Padovani, A., Cruchaga, C., Cairns, N. J., Benussi, L., Wang, Yunpeng, Binetti, G., Ghidoni, R., Forloni, G., Albani, D., Galimberti, D., Fenoglio, C., Serpente, M., Scarpini, E., Clarimón, J., Lleó, A., Wen, Natalie, Blesa, R., Waldö, M Landqvist, Nilsson, K., Nilsson, C., Mackenzie, I. R. A., Hsiung, G-Y R, Mann, D. M. A., Grafman, J., Morris, C. M., Attems, J., Broce, Iris J, Griffiths, T. D., McKeith, I. G., Thomas, A. J., Pietrini, P., Huey, E. D., Wassermann, E. M., Baborie, A., Jaros, E., Tierney, M. C., Pastor, P., Li, Yi, Razquin, C., Ortega-Cubero, S., Alonso, E., Perneczky, R., Diehl-Schmid, J., Alexopoulos, P., Kurz, A., Rainero, I., Rubino, E., Pinessi, L., Barkovich, Matthew J, Rogaeva, E., George-Hyslop, P St, Rossi, G., Tagliavini, F., Giaccone, G., Rowe, J. B., Schlachetzki, J. C. M., Uphill, J., Collinge, J., Mead, S.
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-10 (2018)
Translational psychiatry, vol 8, iss 1
Translational Psychiatry 8(1), 73 (2018). doi:10.1038/s41398-017-0049-7
Translational Psychiatry
Translational psychiatry
Translational psychiatry, vol 8, iss 1
Translational Psychiatry 8(1), 73 (2018). doi:10.1038/s41398-017-0049-7
Translational Psychiatry
Translational psychiatry
Neurodegenerative diseases likely share common underlying pathobiology. Although prior work has identified susceptibility loci associated with various dementias, few, if any, studies have systematically evaluated shared genetic risk across several ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5d0e8b5aec77bea3ed08c7b701c40a
https://doi.org/10.1101/181693
https://doi.org/10.1101/181693
Autor:
Ferrari, Raffaele, Wang, Yunpeng, Vandrovcova, Jana, Guelfi, Sebastian, Witeolar, Aree, Karch, Celeste M, Schork, Andrew J, Fan, Chun C, Brewer, James B, International FTD-Genomics Consortium (IFGC), International Parkinson's Disease Genomics Consortium (IPDGC), International Genomics Of Alzheimer's Project (IGAP), Momeni, Parastoo, Schellenberg, Gerard D, Dillon, William P, Sugrue, Leo P, Hess, Christopher P, Yokoyama, Jennifer S, Bonham, Luke W, Rabinovici, Gil D, Miller, Bruce L, Andreassen, Ole A, Dale, Anders M, Hardy, John, Desikan, Rahul S
Publikováno v:
Journal of neurology, neurosurgery, and psychiatry, vol 88, iss 2
BACKGROUND: Clinical, pathological and genetic overlap between sporadic frontotemporal dementia (FTD), Alzheimer's disease (AD) and Parkinson's disease (PD) has been suggested; however, the relationship between these disorders is still not well under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6103c6e9dcba84a152fa2d81c5f0a9a7
Autor:
Yokoyama, Jennifer S., Karch, Celeste M., Fan, Chun C., Bonham, Luke W., Naomi, Kouri, Ross, Owen A., Rosa, Rademakers, Jungsu, Kim, Yunpeng, Wang, Höglinger, Günter U., Ulrich, Muller, Raffaele, Ferrari, John, Hardy, International FTD-Genomics Consortium (IFGC Ferrari, R, Hernandez, Dg, Nalls, Ma, Rohrer, Jd, Ramasamy, A, Kwok, Jbj, Dobson-Stone, C, Schofield, Pr, Halliday, Gm, Hodges, Jr, Piguet, O, Bartley, L, Thompson, E, Haan, E, Hernández, I, Ruiz, A, Boada, M, Borroni, B, Padovani, A, Cruchaga, C, Cairns, Nj, Benussi, L, Binetti, G, Ghidoni, R, Forloni, G, Albani, D, Galimberti, D, Fenoglio, C, Serpente, M, Scarpini, E, Clarimón, J, Lleó, A, Blesa, R, Landqvist Waldö, M, Nilsson, C, Mackenzie, Ira, Hsiung, Gyr, Mann, Dma, Grafman, J, Morris, Cm, Attems, J, Griffiths, Td, Mckeith, Ig, Thomas, Aj, Pietrini, P, Huey, Ed, Wassermann, Em, Baborie, A, Jaros, E, Tierney, Mc, Pastor, P, Razquin, C, Ortega-Cubero, S, Alonso, E, Perneczky, R, Diehl-Schmid, J, Alexopoulos, P, Kurz, A, Rainero, I, Rubino, E, Pinessi, L, Rogaeva, E, St George-Hyslop, P, Rossi, G, Tagliavini, F, Giaccone, G, Rowe, Jb, Schlachetzki, Jcm, Uphill, J, Collinge, J, Mead, S, Danek, A, Van Deerlin VM, Grossman, M, Trojanowski, Jq, van der Zee, J, Cruts, M, Van Broeckhoven, C, Cappa, Sf, Leber, I, Hannequin, D, Golfier, V, Vercelletto, M, Brice, A, Nacmias, B, Sorbi, S, Bagnoli, S, Piaceri, I, Nielsen, Je, Hjermind, Le, Riemenschneider, M, Mayhaus, M, Ibach, B, Gasparoni, G, Pichler, S, Gu, W, Rossor, Mn, Fox, Nc, Warren, Jd, Spillantini, Mg, Morris, Hr, Rizzu, P, Heutink, P, Snowden, Js, Rollinson, S, Richardson, A, Gerhard, A, Bruni, Ac, Maletta, R, Frangipane, F, Cupidi, C, Bernardi, L, Anfossi, M, Gallo, M, Conidi, Me, Smirne, N, Rademakers, R, Baker, M, Dickson, Dw, Graff-Radford, Nr, Petersen, Rc, Knopman, D, Josephs, Ka, Boeve, Bf, Parisi, Je, Seeley, Ww, Miller, Bl, Karydas, Am, Rosen, H, van Swieten JC, Dopper, Eg, Seelaar, H, Pijnenburg, Yal, Scheltens, P, Logroscino, G, Capozzo, R, Novelli, V, Puca, Aa, Franceschi, M, Postiglione, A, Milan, G, Sorrentino, P, Kristiansen, M, Chiang, Hh, Graff, C, Pasquier, F, Rollin, A, Deramecourt, V, Lebouvier, T, Kapogiannis, D, Ferrucci, L, Pickering-Brown, S, Singleton, Ab, Hardy, J, Momeni, P. )., Parastoo, Momeni, Sugrue, Leo P., Hess, Christopher P., James Barkovich, A., Boxer, Adam L., Seele, William W., Rabinovici, Gil D., Rosen, Howard J., Miller, Bruce L., Schmansky, Nicholas J., Bruce, Fischl, Hyman, Bradley T., Dickson, Dennis W., Schellenberg, Gerard D., Andreassen, Ole A., Dale, Anders M., Desikan, and Rahul S.
Publikováno v:
Acta neuropathologica, vol 133, iss 5
Acta neuropathologica 133(5), 825-837 (2017). doi:10.1007/s00401-017-1693-y
Acta neuropathologica
Yokoyama, JS; Karch, CM; Fan, CC; Bonham, LW; Kouri, N; Ross, OA; et al.(2017). Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. ACTA NEUROPATHOLOGICA, 133(5), 825-837. doi: 10.1007/s00401-017-1693-y. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/78j6x9mk
Acta neuropathologica 133(5), 825-837 (2017). doi:10.1007/s00401-017-1693-y
Acta neuropathologica
Yokoyama, JS; Karch, CM; Fan, CC; Bonham, LW; Kouri, N; Ross, OA; et al.(2017). Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia. ACTA NEUROPATHOLOGICA, 133(5), 825-837. doi: 10.1007/s00401-017-1693-y. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/78j6x9mk
Corticobasal degeneration (CBD), progressive supranuclear palsy (PSP) and a subset of frontotemporal dementia (FTD) are neurodegenerative disorders characterized by tau inclusions in neurons and glia (tauopathies). Although clinical, pathological and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c028786d1d8b4780b82f2e10ff33bb
http://hdl.handle.net/2318/1678636
http://hdl.handle.net/2318/1678636
Autor:
Yokoyama, Jennifer S, Wang, Yunpeng, Schork, Andrew J, Thompson, Wesley K, Karch, Celeste M, Cruchaga, Carlos, McEvoy, Linda K, Witoelar, Aree, Chen, Chi-Hua, Holland, Dominic, Brewer, James B, Franke, Andre, Dillon, William P, Wilson, David M, Mukherjee, Pratik, Hess, Christopher P, Miller, Zachary, Bonham, Luke W, Shen, Jeffrey, Rabinovici, Gil D, Rosen, Howard J, Miller, Bruce L, Hyman, Bradley T, Schellenberg, Gerard D, Karlsen, Tom H, Andreassen, Ole A, Dale, Anders M, Desikan, Rahul S, Alzheimer’s Disease Neuroimaging Initiative
Publikováno v:
JAMA neurology, vol 73, iss 6
ImportanceLate-onset Alzheimer disease (AD), the most common form of dementia, places a large burden on families and society. Although epidemiological and clinical evidence suggests a relationship between inflammation and AD, their relationship is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a41d6c9db4ca4b017fa2d988f584435a
https://escholarship.org/uc/item/8xs2x9g0
https://escholarship.org/uc/item/8xs2x9g0
Autor:
Desikan, Rahul S., Fan, Chun Chieh, Wang, Yunpeng, Schork, Andrew J., Cabral, Howard J., Cupples, L. Adrienne, Thompson, Wesley K., Besser, Lilah, Kukull, Walter A., Holland, Dominic, Chen, Chi-Hua, Brewer, James B., Karow, David S., Kauppi, Karolina, Witoelar, Aree, Karch, Celeste M., Bonham, Luke W., Yokoyama, Jennifer S., Rosen, Howard J., Miller, Bruce L.
Publikováno v:
PLoS Medicine; 3/21/2017, Vol. 14 Issue 3, p1-17, 17p