Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Francesco Amenta"'
Publikováno v:
Mechanisms of Ageing and Development. 74:47-58
The influence of aging on the acetylcholine synthesising and the degrading enzymes choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) was studied in the hippocampus of male Wstar rats at 2 months (young), 12 months (adult) and 27 months
Publikováno v:
Mechanisms of Ageing and Development. 69:119-127
The rat cerebellar cortex represents an interesting animal model for the analysis of age-dependent changes in brain microanatomy and function. Moreover, the cerebellar cortex contains detectable amounts of nerve growth factor (NGF) and express NGF re
The effects of association of cholinergic precursors choline or choline alphoscerate with the cholinesterase inhibitor rivastigmine on acetylcholine levels and [(3)H]hemicholinium-3 binding were assessed in rat frontal cortex, hippocampus and striatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062c8f88f8415c8e3c8ce4bdcc0b04dc
http://hdl.handle.net/11581/115685
http://hdl.handle.net/11581/115685
This paper has reviewed the documentation on the clinical efficacy of choline alphoscerate, a cholinergic precursor, considered as a centrally acting parasympathomimetic drug in dementia disorders and in acute cerebrovascular disease. Thirteen publis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5219c2811c3043578768c47c3133d955
http://hdl.handle.net/11391/164552
http://hdl.handle.net/11391/164552
Publikováno v:
Mechanisms of ageing and development. 76(1)
The present study was designed to investigate age-dependent changes of muscarcinic M1 and M2 cholinergic receptors in the rat hippocampus using radioreceptor assay and autoradiographic techniques with [3H]pirenzepine and [3H]AF-DX 116 as ligands. The
Mossy fibres represent a major intrahippocampal associative pathway. They consist of axons of granule cells of the dentate gyrus and show an age-dependent loss as do the granule cells of the dentate gyrus. The present study was designed to assess whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b3eb5174dd2a32b79ec541387f48359
http://hdl.handle.net/11581/242927
http://hdl.handle.net/11581/242927
Age-related structural changes in the rat cerebellar cortex: effect of choline alfoscerate treatment
The influence of ageing and of 3 months choline alfoscerate treatment on age-related microstructural changes in cerebellar cortex was studied in 3-, 12- and 24-month-old male Sprague-Dawley rats. The number of Purkinje and granule neurons, the densit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3f55aa4e0e24ed63c242e5e43e24af
http://hdl.handle.net/11581/242935
http://hdl.handle.net/11581/242935