Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wayne Tam"'
Publikováno v:
Annals of diagnostic pathology. 56
Merkel cell carcinoma (MCC) is a rare but aggressive neuroendocrine carcinoma of the skin, often associated with polyomavirus and ultra-violet light exposure. Immunosuppression is associated with increased risk of development of MCC, including that a
Autor:
Leandro Cerchietti, Jia Ruan, David M. Hyman, Sonali M. Smith, Morton Coleman, Amelyn Rodriguez, Paul J. Christos, Stephen J. Schuster, Bijal D. Shah, John P. Leonard, Wayne Tam, Peter Martin, Maria Nieves Calvo-Vidal, Jakub Svoboda, Richard R. Furman
Publikováno v:
Blood. 132:2016-2025
We report 5-year follow-up of a multicenter phase 2 study of lenalidomide plus rituximab (LR) as initial treatment of mantle cell lymphoma (MCL). The regimen includes induction and maintenance with the LR doublet. Treatment was continuous until progr
Autor:
Guilin, Tang, Wayne, Tam, Nicholas J, Short, Prithviraj, Bose, David, Wu, Stephanie N, Hurwitz, Adam, Bagg, Heesun J, Rogers, Eric D, Hsi, Andres E, Quesada, Wei, Wang, Roberto N, Miranda, Carlos E, Bueso-Ramos, L Jeffrey, Medeiros, Valentina, Nardi, Robert P, Hasserjian, Daniel A, Arber, Attilio, Orazi, Kathryn, Foucar, Sa A, Wang
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 34(9)
Myeloid/lymphoid neoplasms (M/LN) with 13q12/FLT3 rearrangement have been suggested as candidates for possible inclusion in the World Health Organization classification group of M/LN with eosinophilia (M/LN-eo). We report 12 patients with confirmed F
Autor:
Chi Young, Ok, Kevin T, Trowell, Kyle G, Parker, Karen, Moser, Olga K, Weinberg, Heesun J, Rogers, Kaaren K, Reichard, Tracy I, George, Eric D, Hsi, Carlos E, Bueso-Ramos, Wayne, Tam, Attilio, Orazi, Adam, Bagg, Daniel A, Arber, Robert P, Hasserjian, Sa A, Wang
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 34(1)
JAK2, CALR, and MPL are myeloproliferative neoplasm (MPN)-driver mutations, whereas SF3B1 is strongly associated with ring sideroblasts (RS) in myelodysplastic syndrome (MDS). Concomitant mutations of SF3B1 and MPN-driver mutations out of the context
Autor:
Peter Nørgaard, Stephen Hamilton-Dutoit, Rui Wang, Wayne Tam, Maja Ludvigsen, Henrik Frederiksen, Jesper Stentoft, Preben Johansen, Gustav Mathiasen, Weiwei Zhang, Hans Beier Ommen, Tobias Ramm Eberlein, Martin Bjerregård Pedersen, Giorgio Inghirami, Michael Boe Møller, Wing C. Chan, Johanne Marie Holst, Marcus Celik Hansen, Chao Wang, Andreas Kiesbye Øvlisen, Michael Roost Clausen, Trine Lindhardt Plesner, Francesco d'Amore, Bo Kok Mortensen
Publikováno v:
Holst, J M, Plesner, T L, Pedersen, M B, Frederiksen, H, Møller, M B, Clausen, M R, Hansen, M C, Hamilton-Dutoit, S J, Nørgaard, P, Johansen, P, Eberlein, T R, Mortensen, B K, Mathiasen, G, Øvlisen, A, Wang, R, Wang, C, Zhang, W, Ommen, H B, Stentoft, J, Ludvigsen, M, Tam, W, Chan, W C, Inghirami, G & d'Amore, F 2020, ' Myeloproliferative and lymphoproliferative malignancies occurring in the same patient : A nationwide discovery cohort ', Haematologica, vol. 105, no. 10, pp. 2432-2439 . https://doi.org/10.3324/haematol.2019.225839
Holst, J M, Plesner, T L, Pedersen, M B, Frederiksen, H, Møller, M B, Clausen, M R, Hansen, M C, Hamilton-Dutoit, S J, Nørgaard, P, Johansen, P, Eberlein, T R, Mortensen, B K, Mathiasen, G, Øvlisen, A, Wang, R, Wang, C, Zhang, W, Ommen, H B, Stentoft, J, Ludvigsen, M, Tam, W, Chan, W C, Inghirami, G & d'Amore, F 2020, ' Myeloproliferative and lymphoproliferative malignancies occurring in the same patient : a nationwide discovery cohort ', Haematologica, vol. 105, no. 10, pp. 2432-2439 . https://doi.org/10.3324/haematol.2019.225839
Haematologica
Holst, J M, Plesner, T L, Pedersen, M B, Frederiksen, H, Møller, M B, Clausen, M R, Hansen, M C, Hamilton-Dutoit, S J, Nørgaard, P, Johansen, P, Eberlein, T R, Mortensen, B K, Mathiasen, G, Øvlisen, A, Wang, R, Wang, C, Zhang, W, Ommen, H B, Stentoft, J, Ludvigsen, M, Tam, W, Chan, W C, Inghirami, G & d'Amore, F 2020, ' Myeloproliferative and lymphoproliferative malignancies occurring in the same patient : a nationwide discovery cohort ', Haematologica, vol. 105, no. 10, pp. 2432-2439 . https://doi.org/10.3324/haematol.2019.225839
Haematologica
Myeloid and lymphoid malignancies are postulated to have distinct pathogenic mechanisms. The recent observation that patients with a myeloproliferative neoplasm have an increased risk of developing lymphoproliferative malignancies has challenged this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297ac1db7437d2bd995e9aad4ae2ef95
https://curis.ku.dk/ws/files/256164690/9571_Article_Text_70951_2_10_20200908.pdf
https://curis.ku.dk/ws/files/256164690/9571_Article_Text_70951_2_10_20200908.pdf
Autor:
Jesus G. Berdeja, Ronan T. Swords, Farhad Sedarati, Michael R. Savona, Iwona Pawlikowska-Dobler, Bruce J. Dezube, Ajeeta B Dash, Joshua F. Zeidner, Douglas V. Faller, Steven Coutre, Jose C. Cruz, James M. Foran, Hélène M. Faessel, Saran Vardhanabhuti, Wayne Tam, Harry P. Erba, Michael B. Maris
Publikováno v:
Blood. 131:1415-1424
Pevonedistat (TAK-924/MLN4924) is a novel inhibitor of NEDD8-activating enzyme (NAE) with single-agent activity in relapsed/refractory acute myeloid leukemia (AML). We performed a phase 1b study of pevonedistat (PEV) with azacitidine (AZA) based on s
Autor:
M. Ponzoni, Wayne Tam, J.H.J.M. van Krieken, Lijuan Deng, Praveen Jain, Luis Fayad, Jianxiang Wang, Govind Bhagat, Ganiraju C. Manyam, Hagop M. Kantarjian, L. J. Medeiros, Y Liu, Ken H. Young, Karen Dybkær, Jorge E. Cortes, C. Visco, Yong Li, Jane N. Winter, Zhilei Yao, Robert Z. Orlowski, Anna Ferreri, Alexandar Tzankov, Zijun Y. Xu-Monette, M A Piris, Eric D. Hsi, Yongping Song, Michael Boe Møller
Publikováno v:
Leukemia, 32, 353-363
Yao, Z, Deng, L, Xu-Monette, Z Y, Manyam, G C, Jain, P, Tzankov, A, Visco, C, Bhagat, G, Wang, J, Dybkaer, K, Tam, W, Hsi, E D, van Krieken, J H, Ponzoni, M, Ferreri, A J M, Møller, M B, Winter, J N, Piris, M A, Fayad, L, Liu, Y, Song, Y, Orlowski, R Z, Kantarjian, H, Medeiros, L J, Li, Y, Cortes, J & Young, K H 2018, ' Concordant bone marrow involvement of diffuse large B-cell lymphoma represents a distinct clinical and biological entity in the era of immunotherapy ', Leukemia, vol. 32, no. 2, pp. 353-363 . https://doi.org/10.1038/leu.2017.222
Leukemia, 32, 2, pp. 353-363
Yao, Z, Deng, L, Xu-Monette, Z Y, Manyam, G C, Jain, P, Tzankov, A, Visco, C, Bhagat, G, Wang, J, Dybkær, K, Tam, W, Hsi, E D, van Krieken, J H, Ponzoni, M, Ferreri, A J M, Møller, M B, Winter, J N, Piris, M A, Fayad, L, Liu, Y, Song, Y, Orlowski, R Z, Kantarjian, H, Medeiros, L J, Li, Y, Cortes, J & Young, K H 2018, ' Concordant bone marrow involvement of diffuse large B-cell lymphoma represents a distinct clinical and biological entity in the era of immunotherapy ', Leukemia, vol. 32, no. 2, pp. 353–363 . https://doi.org/10.1038/leu.2017.222
Yao, Z, Deng, L, Xu-Monette, Z Y, Manyam, G C, Jain, P, Tzankov, A, Visco, C, Bhagat, G, Wang, J, Dybkaer, K, Tam, W, Hsi, E D, van Krieken, J H, Ponzoni, M, Ferreri, A J M, Møller, M B, Winter, J N, Piris, M A, Fayad, L, Liu, Y, Song, Y, Orlowski, R Z, Kantarjian, H, Medeiros, L J, Li, Y, Cortes, J & Young, K H 2018, ' Concordant bone marrow involvement of diffuse large B-cell lymphoma represents a distinct clinical and biological entity in the era of immunotherapy ', Leukemia, vol. 32, no. 2, pp. 353-363 . https://doi.org/10.1038/leu.2017.222
Leukemia, 32, 2, pp. 353-363
Yao, Z, Deng, L, Xu-Monette, Z Y, Manyam, G C, Jain, P, Tzankov, A, Visco, C, Bhagat, G, Wang, J, Dybkær, K, Tam, W, Hsi, E D, van Krieken, J H, Ponzoni, M, Ferreri, A J M, Møller, M B, Winter, J N, Piris, M A, Fayad, L, Liu, Y, Song, Y, Orlowski, R Z, Kantarjian, H, Medeiros, L J, Li, Y, Cortes, J & Young, K H 2018, ' Concordant bone marrow involvement of diffuse large B-cell lymphoma represents a distinct clinical and biological entity in the era of immunotherapy ', Leukemia, vol. 32, no. 2, pp. 353–363 . https://doi.org/10.1038/leu.2017.222
In diffuse large B-cell lymphoma (DLBCL), the clinical and biological significance of concordant and discordant bone marrow (BM) involvement have not been well investigated. We evaluated 712 de novo DLBCL patients with front-line rituximab-containing
Autor:
Duane C. Hassane, Elizabeth Margolskee, Daniel A. Arber, Robert P. Hasserjian, Attilio Orazi, Sa A. Wang, Wayne Tam, Susan Mathew, Jean Oak, Chi Young Ok
Publikováno v:
American Journal of Clinical Pathology. 148:49-57
Objectives Three situations qualify as myelodysplastic syndrome, unclassifiable (MDS-U): (1) refractory cytopenia with dysplasia and 1% blasts in peripheral blood (BL), (2) pancytopenia with unilineage dysplasia (Pan), and (3) persistent cytopenia, l
Autor:
Shabnam Momtahen, Constantin Friedman, Gerard J. Nuovo, Cynthia M. Magro, Shalini Verma, Wayne Tam, Ronnie M. Abraham
Publikováno v:
Annals of Diagnostic Pathology. 25:85-91
Monocytes are critical components of the innate immune system and they can differentiate into dendritic cells (DCs). Cutaneous neoplasms of dendritic cell origin are uncommon and mostly represented by histiocytic lesions derived primarily from Langer
Publikováno v:
Acta cytologica. 62(2)
Objectives: We sought to assess the utility and limitations of both flow cytometry (FC) and cytology for the analysis of cerebrospinal fluid (CSF) in a practical clinical setting. Methods: A total of 393 consecutive CSF samples from 171 patients subm