Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Agnieszka Wozniak"'
Autor:
Bernd Kasper, Palma Dileo, Zsuzsanna Papai, Axelle Nzokirantevye, Antoine Italiano, Charlotte Benson, Katerina Kopeckova, Saskia Litière, Isabelle Vanden Bempt, Facundo Zaffaroni, Eva Wardelmann, A. Lecesne, Olivier Mir, Nasim Ali, Agnieszka Wozniak, Patrick Schöffski, Franka Menge, Sandrine Marreaud, Sophie Cousin, Jean-Yves Blay, Hans Gelderblom
Publikováno v:
European Journal of Cancer, 134, 62-74. ELSEVIER SCI LTD
Background Gastrointestinal stromal tumour (GIST) is commonly treated with tyrosine kinase inhibitors (TKIs), but most patients ultimately develop secondary resistance. Cabozantinib, a multi-targeted TKI inhibitor, has activity in patient-derived GIS
Autor:
Hazem Wafa, Jasmien Cornillie, Patrick Schöffski, Agnieszka Wozniak, Haifu Li, Ulla Vanleeuw, Jasmien Wellens, Diether Lambrechts, Friedl Sinnaeve, Maria Debiec-Rychter, Raf Sciot, Yannick Wang, Daphne Hompes, Bram Boeckx, Yemarshet K. Gebreyohannes, Marguerite Stas
Publikováno v:
Molecular Cancer Therapeutics. 18:1168-1178
Soft-tissue sarcomas (STS) represent a heterogeneous group of rare, malignant tumors of mesenchymal origin. Reliable in vivo sarcoma research models are scarce. We aimed to establish and characterize histologically and molecularly stable patient-deri
Autor:
Gabrielle Couchy, Evelyne Lerut, Virginie Verkarre, Sylvie Job, Jean-Pascal Machiels, Benoit Beuselinck, Jessica Zucman-Rossi, Aurélien de Reyniès, Thomas Van Brussel, Jean-Jacques Patard, Annelies Verbiest, Stéphane Oudard, Diether Lambrechts, Arnaud Mejean, Agnieszka Wozniak
Publikováno v:
Clinical Genitourinary Cancer. 16:266-273
Background Clear-cell renal-cell carcinoma (ccRCC) is characterized by loss of a functional Von Hippel–Lindau (VHL) protein. We investigated the potential of 3 single nucleotide polymorphisms (SNPs) in VHL as biomarkers in metastatic ccRCC (m-ccRCC
Autor:
Annelies Verbiest, Nathalie Rioux-Leclercq, Benoit Beuselinck, Steven Joniau, Aurélien de Reyniès, Laure Caruana, Brigitte Laguerre, Kathleen Van den Eynde, Gabrielle Couchy, Hendrik Van Poppel, Jessica Zucman-Rossi, Evelyne Lerut, Agnieszka Wozniak, Sylvie Job, Raymond Oyen
Publikováno v:
Clinical Genitourinary Cancer
Clinical Genitourinary Cancer, Elsevier, 2018, 16 (3), pp.e605-e612. ⟨10.1016/j.clgc.2017.10.017⟩
Clinical Genitourinary Cancer, 2018, 16 (3), pp.e605-e612. ⟨10.1016/j.clgc.2017.10.017⟩
Clinical Genitourinary Cancer, Elsevier, 2018, 16 (3), pp.e605-e612. ⟨10.1016/j.clgc.2017.10.017⟩
Clinical Genitourinary Cancer, 2018, 16 (3), pp.e605-e612. ⟨10.1016/j.clgc.2017.10.017⟩
International audience; Background: We previously described 4 molecular subtypes of metastatic clear cell renal cell carcinoma (mccRCC), named ccrcc1-4 (Beuselinck et al, 2015). These have both prognostic and predictive value for patients treated wit
Autor:
Jasmien Cornillie, Agnieszka Wozniak, Patrick Schöffski, Tom van Cann, Daphne Hompes, Raf Sciot, Ignace Vergote, Maria Debiec-Rychter
Publikováno v:
Oncology Research and Treatment. 41:206-213
Background: Leiomyosarcoma is a common subtype of soft tissue sarcoma originating from smooth muscle. We evaluated the clinical course and treatment outcome of patients with metastatic leiomyosarcoma. Methods: We retrospectively reviewed the records
Autor:
Yemarshet K. Gebreyohannes, Jasmien Wellens, Daphne Hompes, Patrick Schöffski, Agnieszka Wozniak, Britt Van Renterghem, Maria Debiec-Rychter, Jasmien Cornillie, Raf Sciot, Nathalie Van Winkel
Publikováno v:
BMC Cancer
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Background Soft tissue sarcoma (STS) comprises a family of rare, heterogeneous tumors of mesenchymal origin. Single-agent doxorubicin remains the first-line standard-of-care treatment for advanced and inoperable STS, but response rates are only aroun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::255416e11d56f739ae90012cfcceaaca
https://lirias.kuleuven.be/handle/123456789/639986
https://lirias.kuleuven.be/handle/123456789/639986
Autor:
Patrick Schöffski, Vanessa Vanspauwen, Thomas Van Looy, Anna Quattrone, Agnieszka Wozniak, Piotr Rutkowski, Giuseppe Floris, Raf Sciot, Barbara Dewaele, Maria Debiec-Rychter
Publikováno v:
Modern Pathology. 27:1510-1520
Insufficiency of phosphatase and tensin homolog (PTEN) occurs in numerous tumor types and has been implicated as a resistance mechanism to receptor tyrosine kinase-targeted therapies in human cancer. In this study, we have performed a comprehensive m
Autor:
Maria Debiec-Rychter, Agnieszka Wozniak, Patrick Schöffski, Sebastian Bauer, Piotr Rutkowski, Alan Anthoney, Michela Lia, Branko Zakotnik, Jozef Sufliarsky, Evelyne Lerut, Laurence Albiges, Sandrine Marreaud, Bernard Escudier, Viktor Grünwald, Sandra Collette, Lars H. Lindner, Tiana Raveloarivahy, Carla M.L. van Herpen
Publikováno v:
European Journal of Cancer, 87, 147-163
European Journal of Cancer, 87, pp. 147-163
European Journal of Cancer, 87, pp. 147-163
Purpose Papillary renal-cell carcinoma type 1 (PRCC1) is associated with MET gene alterations. Our phase II trial prospectively assessed the efficacy and safety of crizotinib in patients with advanced/metastatic PRCC1 with or without MET mutations (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c378fbbab578502d583fe418c6de4fac
http://hdl.handle.net/2066/181518
http://hdl.handle.net/2066/181518
Autor:
Patrick Schöffski, Maria Debiec-Rychter, Vanessa Vanspauwen, Janusz A. Siedlecki, Piotr Rutkowski, Joanna Przybyl, Agnieszka Wozniak, Raf Sciot, Ignace Samson
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 53:505-513
Introduction Synovial sarcoma (SynSa) is an aggressive mesenchymal tumor, comprising approximately 10% of all soft tissue sarcomas. Over half of SynSa patients develop metastasis or local recurrence, but the underlying molecular mechanisms of the agg
Autor:
Agnieszka Wozniak, Herman Burger, Axelle Nzokirantevye, Erik A.C. Wiemer, Marcel Smid, Raf Sciot, Patrick Schöffski, Stefan Sleijfer, Giuseppe Floris
Publikováno v:
European Journal of Cancer, 75, 33-40. Elsevier Ltd.
Background Recent phase II and III clinical trials demonstrated anti-tumour activity of eribulin, a tubulin-interacting cytotoxic agent, in patients with metastatic soft tissue sarcoma (STS). In this exploratory study, we aimed to identify putative m