Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Nicholas J. Timpson"'
Publikováno v:
Roberts, V, Main, B, Timpson, N J & Haworth, S 2020, ' Genome wide association study identifies genetic associations with perceived age ', Journal of Investigative Dermatology . https://doi.org/10.1016/j.jid.2020.03.970
The Journal of Investigative Dermatology
The Journal of Investigative Dermatology
Failure of dermal protection or repair mechanisms might lead to visibly aged skin. The study aimed to identify genetic associations with perceived age. A genome-wide association study was undertaken in 423,992 adult participants of UK Biobank, using
Autor:
Laura J, Corbin, Stephen J, White, Amy E, Taylor, Christopher M, Williams, Kurt, Taylor, Marion T, van den Bosch, Jack E, Teasdale, Matthew, Jones, Mark, Bond, Matthew T, Harper, Louise, Falk, Alix, Groom, Georgina G J, Hazell, Lavinia, Paternoster, Marcus R, Munafò, Børge G, Nordestgaard, Anne, Tybjærg-Hansen, Stig E, Bojesen, Caroline, Relton, Josine L, Min, George, Davey Smith, Andrew D, Mumford, Alastair W, Poole, Nicholas J, Timpson
Publikováno v:
Circulation research. 130(3)
DNA hypomethylation at theWe conducted multiple independent experiments to assess whether DNA hypomethylation atObservationally, DNA methylation atSmoking-induced epigenetic DNA hypomethylation at
Autor:
Nicholas J. Timpson, Ko Willems van Dijk, David A. Hughes, Frits R. Rosendaal, Jan B. van Klinken, Dennis O. Mook-Kanamori, Ruifang Li-Gao, Renée de Mutsert
Publikováno v:
Diabetes, 70(12), 2932-2946. American Diabetes Association Inc.
Diabetes, 70(12), 2932-2946. AMER DIABETES ASSOC
Li-Gao, R, Hughes, D, van Klinken, J B, de Mutsert, R, Rosendaal, F R, Mook-Kanamori, D O, Timpson, N J & Willems van Dijk, K 2021, ' Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism ', Diabetes, vol. 70, no. 12, pp. 2932–2946 . https://doi.org/10.2337/db21-0397
Diabetes, 70(12), 2932-2946. AMER DIABETES ASSOC
Li-Gao, R, Hughes, D, van Klinken, J B, de Mutsert, R, Rosendaal, F R, Mook-Kanamori, D O, Timpson, N J & Willems van Dijk, K 2021, ' Genetic Studies of Metabolomics Change After a Liquid Meal Illuminate Novel Pathways for Glucose and Lipid Metabolism ', Diabetes, vol. 70, no. 12, pp. 2932–2946 . https://doi.org/10.2337/db21-0397
Humans spend the greater part of the day in a postprandial state. However, the genetic basis of postprandial blood measures is relatively uncharted territory. We set out to examine the genetics of variation in concentrations of postprandial metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::000718a656634684981d7975cd84f1b7
https://pure.amc.nl/en/publications/genetic-studies-of-metabolomics-change-after-a-liquid-meal-illuminate-novel-pathways-for-glucose-and-lipid-metabolism(05873820-80c8-4d50-9c79-a0c18de18ffe).html
https://pure.amc.nl/en/publications/genetic-studies-of-metabolomics-change-after-a-liquid-meal-illuminate-novel-pathways-for-glucose-and-lipid-metabolism(05873820-80c8-4d50-9c79-a0c18de18ffe).html
Autor:
Nicholas J. Timpson, Haoyu Wu, Tianyuan Lu, John R. B. Perry, Celia M. T. Greenwood, Despoina Manousaki, Ken K. Ong, Vincenzo Forgetta, J. Brent Richards
Publikováno v:
Lu, T, Forgetta, V, Wu, H, Perry, J R B, Ong, K K, Greenwood, C M T, Timpson, N J, Manoousaki, D & Richards, J B 2021, ' A Polygenic Risk Score to Predict Future Adult Short Stature Among Children ', Journal of Clinical Endocrinology and Metabolism, vol. 106, no. 7, dgab215, pp. 1918-1928 . https://doi.org/10.1210/clinem/dgab215
The Journal of Clinical Endocrinology and Metabolism
The Journal of Clinical Endocrinology and Metabolism
Context Adult height is highly heritable, yet no genetic predictor has demonstrated clinical utility compared to mid-parental height. Objective To develop a polygenic risk score for adult height and evaluate its clinical utility. Design A polygenic r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf25c5f14fa14f1e968493bf7e2dd44d
Autor:
Inês Barroso, Gail Davies, H.-Erich Wichmann, Bjarke Feenstra, Peter Vollenweider, Nicholas J. Timpson, Alan F. Wright, Frank Geller, Gérard Waeber, John M. Starr, Benjamin M. Neale, George Davey Smith, Tõnu Esko, Ruth J. F. Loos, Andrew A. Hicks, Pedro Marques-Vidal, Dorret I. Boomsma, Harry Campbell, Zoltán Kutalik, David M. Evans, Scott D. Gordon, Eva Albrecht, Peter P. Pramstaller, Leena Peltonen, Jing Hua Zhao, Lavinia Paternoster, Thomas Hansen, Massimo Mangino, Fazil Aliev, Beate St Pourcain, Panos Deloukas, Heather A. Boyd, Guillaume Paré, Marco P. Boks, Monique M.B. Breteler, Jouke-Jan Hottenga, Xin Li, Kari Stefansson, Ian J. Deary, Jari Lahti, Inga Prokopenko, Nicholas Eriksson, Lili Milani, Nicholas J. Wareham, Jordan W. Smoller, Norman Klopp, Lynn Cherkas, Reedik Mägi, Margaret J. Wright, Peter Kraft, Jacques S. Beckmann, Brenda W.J.H. Penninx, Gabriel Cuellar-Partida, André G. Uitterlinden, Fernando Rivadeneira, Wendy L. McArdle, Johan G. Eriksson, Jiali Han, Jennifer E. Huffman, Andres Metspalu, J.M. Vink, Frank J. A. van Rooij, Christian Gieger, M. Arfan Ikram, Cecilia M. Lindgren, Aarno Palotie, Daniel I. Chasman, Joyce Y. Tung, Liang-Dar Hwang, David A. Hinds, Elisabeth Widen, Caroline Hayward, Michelle Luciano, Johannes H. Smit, Gonneke Willemsen, Dale R. Nyholt, Carolina Medina-Gomez, Nicole M. Warrington, Teemu Palviainen, Stacy Steinberg, Kay-Tee Khaw, Kevin S. O’Connell, Bettina Konte, Gudmar Thorleifsson, Eco J. C. de Geus, John P. Kemp, Mads Melbye, Mark I. McCarthy, Sarah E. Medland, Jaakko Kaprio, Cameron D. Palmer, Joel N. Hirschhorn, Ina Giegling, Scott Melville, Thomas Werge, Nicole Soranzo, Sigurdur H. Magnusson, Maris Teder-Laving, Hreinn Stefansson, Kauko Heikkilä, Cornelia M. van Duijn, David L. Duffy, Samuli Ripatti, Igor Rudan, Annette M. Hartmann, Ole A. Andreassen, Mari Nelis, Ozren Polasek, Vincent Mooser, Mousheng Xu, Eero Vuoksimaa, Katri Räikkönen, Nicholas G. Martin, Dan Rujescu, Tim D. Spector, Dawn M. Waterworth, Danielle M. Dick, Roel A. Ophoff
Publikováno v:
Cuellar-Partida, G, Tung, J Y, Eriksson, N, Albrecht, E, Aliev, F, Andreassen, O A, Barroso, I, Beckmann, J S, Boks, M P, Boomsma, D I, Boyd, H A, Breteler, M M B, Campbell, H, Chasman, D I, Cherkas, L F, Davies, G, de Geus, E J C, Deary, I J, Deloukas, P, Dick, D M, Duffy, D L, Eriksson, J G, Esko, T, Feenstra, B, Geller, F, Gieger, C, Giegling, I, Gordon, S D, Han, J, Hansen, T F, Hartmann, A M, Hayward, C, Heikkila, K, Hicks, A A, Hirschhorn, J N, Hottenga, J-J, Huffman, J E, Hwang, L-D, Ikram, M A, Kaprio, J, Kemp, J P, Khaw, K-T, Klopp, N, Konte, B, Kutalik, Z, Lahti, J, Li, X, Loos, R J F, Luciano, M, Magnusson, S H, Mangino, M, Marques-Vidal, P, Martin, N G, McArdle, W L, McCarthy, M I, Medina-Gomez, C, Melbye, M, Melville, S A, Metspalu, A, Milani, L, Mooser, V, Nelis, M, Nyholt, D R, O'Connell, K S, Ophoff, R A, Palmer, C, Palotie, A, Palviainen, T, Pare, G, Paternoster, L, Peltonen, L, Penninx, B W J H, Polasek, O, Pramstaller, P P, Prokopenko, I, Raikkonen, K, Ripatti, S, Rivadeneira, F, Rudan, I, Rujescu, D, Smit, J H, Smith, G D, Smoller, J W, Soranzo, N, Spector, T D, Pourcain, B S, Starr, J M, Stefansson, H, Steinberg, S, Teder-Laving, M, Thorleifsson, G, Stefansson, K, Timpson, N J, Uitterlinden, A G, van Duijn, C M, van Rooij, F J A, Vink, J M, Vollenweider, P, Vuoksimaa, E, Waeber, G, Wareham, N J, Warrington, N, Waterworth, D, Werge, T, Wichmann, H-E, Widen, E, Willemsen, G, Wright, A F, Wright, M J, Xu, M, Zhao, J H, Kraft, P, Hinds, D A, Lindgren, C M, Magi, R, Neale, B M, Evans, D M & Medland, S E 2021, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour, vol. 5, pp. 59-70 . https://doi.org/10.1038/s41562-020-00956-y
Partida, G C, Tung, J Y, Eriksson, N, Albrecht, E, Aliev, F, Andreassen, O A, Barroso, I, Beckmann, J S, Boks, M P, Boomsma, D I, Boyd, H A, Breteler, M MB, Campbell, H, Chasman, D I, Cherkas, L F, Davies, G, de Geus, E JC, Deary, I J, Deloukas, P, Dick, D M, Duffy, D L, Eriksson, J G, Esko, T, Feenstra, B, Geller, F, Gieger, C, Giegling, I, Gordon, S D, Han, J, Hansen, T F, Hartmann, A M, Hayward, C, Heikkilä, K, Hicks, A A, Hirschhorn, J N, Hottenga, J-J, Huffman, J E, Hwang, L-D, Ikram, M A, Kaprio, J, Kemp, J P, Khaw, K-T, Klopp, N, Konte, B, Kutalik, Z, Lahti, J, Li, X, Loos, R JF, Luciano, M, Magnusson, S H, Mangino, M, Marques-Vidal, P, Martin, N G, McArdle, W L, McCarthy, M I, Medina-Gomez, C, Melbye, M, Melville, S A, Metspalu, A, Milani, L, Mooser, V, Nelis, M, Nyholt, D R, O’Connell, K S, Ophoff, R A, Palmer, C, Palotie, A, Palviainen, T, Pare, G, Paternoster, L, Peltonen, L, Penninx, B WJH, Polasek, O, Pramstaller, P P, Prokopenko, I, Raikkonen, K, Ripatti, S, Rivadeneira, F, Rudan, I, Rujescu, D, Smit, J H, Smith, G D, Smoller, J W, Soranzo, N, Spector, T D, St Pourcain, B, Starr, J M, Stefánsson, H, Steinberg, S, Teder-Laving, M, Thorleifsson, G, Stefansson, K, Timpson, N J, Uitterlinden, A G, van Duijn, C M, van Rooij, F JA, Vink, J M, Vollenweider, P, Vuoksimaa, E, Waeber, G, Wareham, N J, Warrington, N, Waterworth, D, Werge, T, Wichmann, H-E, Widen, E, Willemsen, G, Wright, A F, Wright, M J, Xu, M, Zhao, J H, Kraft, P, Hinds, D A, Lindgren, C M, Magi, R, Neale, B M, Evans, D M & Medland, S E 2020, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour . https://doi.org/10.1038/s41562-020-00956-y
Cuellar-Partida, G, Tung, J Y, Eriksson, N, Albrecht, E, Aliev, F, Andreassen, O A, Barroso, I, Beckmann, J S, Boks, M P, Boomsma, D I, Boyd, H A, Breteler, M M B, Campbell, H, Chasman, D I, Cherkas, L F, Davies, G, de Geus, E J C, Deary, I J, Deloukas, P, Dick, D M, Duffy, D L, Eriksson, J G, Esko, T, Feenstra, B, Geller, F, Gieger, C, Giegling, I, Gordon, S D, Han, J, Hansen, T F, Hartmann, A M, Hayward, C, Heikkilä, K, Hicks, A A, Hirschhorn, J N, Hottenga, J J, Huffman, J E, Hwang, L D, Ikram, M A, Kaprio, J, Kemp, J P, Khaw, K T, Klopp, N, Konte, B, Kutalik, Z, Lahti, J, Li, X, Loos, R J F, Luciano, M, Magnusson, S H, Mangino, M, Marques-Vidal, P, Martin, N G, McArdle, W L, McCarthy, M I, Medina-Gomez, C, Melbye, M, Melville, S A, Metspalu, A, Milani, L, Mooser, V, Nelis, M, Nyholt, D R, O’Connell, K S, Ophoff, R A, Palmer, C, Palotie, A, Palviainen, T, Pare, G, Paternoster, L, Peltonen, L, Penninx, B W J H, Polasek, O, Pramstaller, P P, Prokopenko, I, Raikkonen, K, Ripatti, S, Rivadeneira, F, Rudan, I, Rujescu, D, Smit, J H, Smith, G D, Smoller, J W, Soranzo, N, Spector, T D, Pourcain, B S, Starr, J M, Stefánsson, H, Steinberg, S, Teder-Laving, M, Thorleifsson, G, Stefánsson, K, Timpson, N J, Uitterlinden, A G, van Duijn, C M, van Rooij, F J A, Vink, J M, Vollenweider, P, Vuoksimaa, E, Waeber, G, Wareham, N J, Warrington, N, Waterworth, D, Werge, T, Wichmann, H E, Widen, E, Willemsen, G, Wright, A F, Wright, M J, Xu, M, Zhao, J H, Kraft, P, Hinds, D A, Lindgren, C M, Mägi, R, Neale, B M, Evans, D M & Medland, S E 2021, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour, vol. 5, no. 1, pp. 59-70 . https://doi.org/10.1038/s41562-020-00956-y
Nature Human Behaviour, 5, 1, pp. 59-70
Nature Human Behaviour, 5(1), 59-70. Nature Publishing Group
Nat Hum Behav
Nature Human Behaviour, 5(1), 59-70. Springer Nature
Nature Human Behaviour
Nat. Hum. Behav. 5, 59–70 (2021)
Nature Human Behaviour, 5, 59-70
Nature human behaviour 5(1), 59-70 (2021). doi:10.1038/s41562-020-00956-y
Cuellar-Partida, G, Deloukas, P, Kemp, J P, McArdle, W L, Paternoster, L, Davey Smith, G, Timpson, N J, Medland, S E & al., E 2020, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour, vol. 5, pp. 59–70 . https://doi.org/10.1038/s41562-020-00956-y
Partida, G C, Tung, J Y, Eriksson, N, Albrecht, E, Aliev, F, Andreassen, O A, Barroso, I, Beckmann, J S, Boks, M P, Boomsma, D I, Boyd, H A, Breteler, M MB, Campbell, H, Chasman, D I, Cherkas, L F, Davies, G, de Geus, E JC, Deary, I J, Deloukas, P, Dick, D M, Duffy, D L, Eriksson, J G, Esko, T, Feenstra, B, Geller, F, Gieger, C, Giegling, I, Gordon, S D, Han, J, Hansen, T F, Hartmann, A M, Hayward, C, Heikkilä, K, Hicks, A A, Hirschhorn, J N, Hottenga, J-J, Huffman, J E, Hwang, L-D, Ikram, M A, Kaprio, J, Kemp, J P, Khaw, K-T, Klopp, N, Konte, B, Kutalik, Z, Lahti, J, Li, X, Loos, R JF, Luciano, M, Magnusson, S H, Mangino, M, Marques-Vidal, P, Martin, N G, McArdle, W L, McCarthy, M I, Medina-Gomez, C, Melbye, M, Melville, S A, Metspalu, A, Milani, L, Mooser, V, Nelis, M, Nyholt, D R, O’Connell, K S, Ophoff, R A, Palmer, C, Palotie, A, Palviainen, T, Pare, G, Paternoster, L, Peltonen, L, Penninx, B WJH, Polasek, O, Pramstaller, P P, Prokopenko, I, Raikkonen, K, Ripatti, S, Rivadeneira, F, Rudan, I, Rujescu, D, Smit, J H, Smith, G D, Smoller, J W, Soranzo, N, Spector, T D, St Pourcain, B, Starr, J M, Stefánsson, H, Steinberg, S, Teder-Laving, M, Thorleifsson, G, Stefansson, K, Timpson, N J, Uitterlinden, A G, van Duijn, C M, van Rooij, F JA, Vink, J M, Vollenweider, P, Vuoksimaa, E, Waeber, G, Wareham, N J, Warrington, N, Waterworth, D, Werge, T, Wichmann, H-E, Widen, E, Willemsen, G, Wright, A F, Wright, M J, Xu, M, Zhao, J H, Kraft, P, Hinds, D A, Lindgren, C M, Magi, R, Neale, B M, Evans, D M & Medland, S E 2020, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour . https://doi.org/10.1038/s41562-020-00956-y
Cuellar-Partida, G, Tung, J Y, Eriksson, N, Albrecht, E, Aliev, F, Andreassen, O A, Barroso, I, Beckmann, J S, Boks, M P, Boomsma, D I, Boyd, H A, Breteler, M M B, Campbell, H, Chasman, D I, Cherkas, L F, Davies, G, de Geus, E J C, Deary, I J, Deloukas, P, Dick, D M, Duffy, D L, Eriksson, J G, Esko, T, Feenstra, B, Geller, F, Gieger, C, Giegling, I, Gordon, S D, Han, J, Hansen, T F, Hartmann, A M, Hayward, C, Heikkilä, K, Hicks, A A, Hirschhorn, J N, Hottenga, J J, Huffman, J E, Hwang, L D, Ikram, M A, Kaprio, J, Kemp, J P, Khaw, K T, Klopp, N, Konte, B, Kutalik, Z, Lahti, J, Li, X, Loos, R J F, Luciano, M, Magnusson, S H, Mangino, M, Marques-Vidal, P, Martin, N G, McArdle, W L, McCarthy, M I, Medina-Gomez, C, Melbye, M, Melville, S A, Metspalu, A, Milani, L, Mooser, V, Nelis, M, Nyholt, D R, O’Connell, K S, Ophoff, R A, Palmer, C, Palotie, A, Palviainen, T, Pare, G, Paternoster, L, Peltonen, L, Penninx, B W J H, Polasek, O, Pramstaller, P P, Prokopenko, I, Raikkonen, K, Ripatti, S, Rivadeneira, F, Rudan, I, Rujescu, D, Smit, J H, Smith, G D, Smoller, J W, Soranzo, N, Spector, T D, Pourcain, B S, Starr, J M, Stefánsson, H, Steinberg, S, Teder-Laving, M, Thorleifsson, G, Stefánsson, K, Timpson, N J, Uitterlinden, A G, van Duijn, C M, van Rooij, F J A, Vink, J M, Vollenweider, P, Vuoksimaa, E, Waeber, G, Wareham, N J, Warrington, N, Waterworth, D, Werge, T, Wichmann, H E, Widen, E, Willemsen, G, Wright, A F, Wright, M J, Xu, M, Zhao, J H, Kraft, P, Hinds, D A, Lindgren, C M, Mägi, R, Neale, B M, Evans, D M & Medland, S E 2021, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour, vol. 5, no. 1, pp. 59-70 . https://doi.org/10.1038/s41562-020-00956-y
Nature Human Behaviour, 5, 1, pp. 59-70
Nature Human Behaviour, 5(1), 59-70. Nature Publishing Group
Nat Hum Behav
Nature Human Behaviour, 5(1), 59-70. Springer Nature
Nature Human Behaviour
Nat. Hum. Behav. 5, 59–70 (2021)
Nature Human Behaviour, 5, 59-70
Nature human behaviour 5(1), 59-70 (2021). doi:10.1038/s41562-020-00956-y
Cuellar-Partida, G, Deloukas, P, Kemp, J P, McArdle, W L, Paternoster, L, Davey Smith, G, Timpson, N J, Medland, S E & al., E 2020, ' Genome-wide association study identifies 48 common genetic variants associated with handedness ', Nature Human Behaviour, vol. 5, pp. 59–70 . https://doi.org/10.1038/s41562-020-00956-y
Handedness, a consistent asymmetry in skill or use of the hands, has been studied extensively because of its relationship with language and the over-representation of left-handers in some neurodevelopmental disorders. Using data from the UK Biobank,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::986a1504a38fc87e9588fa425872923b
https://curis.ku.dk/portal/da/publications/genomewide-association-study-identifies-48-common-genetic-variants-associated-with-handedness(3aa476e7-e13d-48f1-af0d-544a2ee787fd).html
https://curis.ku.dk/portal/da/publications/genomewide-association-study-identifies-48-common-genetic-variants-associated-with-handedness(3aa476e7-e13d-48f1-af0d-544a2ee787fd).html
Autor:
Nicholas J. Timpson, Patrik K. E. Magnusson, Anders Esberg, Ingegerd Johansson, Simon Haworth, Ralf Kuja-Halkola, P. Lif Holgerson, Paul W. Franks
Publikováno v:
Haworth, S, Esberg, A, Lif Holgerson, P, Kuja-Halkola, R, Timpson, N J, Magnusson, P K E, Franks, P W & Johansson, I 2020, ' Heritability of Caries Scores, Trajectories and Disease Subtypes ', Journal of Dental Research .
Journal of Dental Research
University of Bristol-PURE
Journal of Dental Research
University of Bristol-PURE
Previous studies report that dental caries is partially heritable, but there is uncertainty in the magnitude of genetic effects and little understanding of how genetic factors might influence caries progression or caries subtypes. This study aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfeb481d125ce7f0bd9a7dfbb1c85ff3
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167627
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-167627
Autor:
George Davey Smith, Nicholas J. Timpson, Mats Eliasson, Andrew A Crawford, Clemens Kirschbaum, Tommy Olsson, Shah Ebrahim, Brian R. Walker, Stefan Söderberg, Debbie A Lawlor, Lee Murphy, Rebecca M. Reynolds, Naveed Sattar
Publikováno v:
Crawford, A, Söderberg, S, Kirschbaum, C, Murphy, L, Eliasson, M, Ebrahim, S, Davey Smith, G, Olsson, T, Sattar, N A, Lawlor, D, Timpson, N, Reynolds, R M & Walker, B R 2019, ' Morning plasma cortisol as a cardiovascular risk factor : Findings from prospective cohort and Mendelian randomization studies ', European Journal of Endocrinology, vol. 181, no. 4, pp. 429 . https://doi.org/10.1530/EJE-19-0161
European Journal of Endocrinology
Crawford, A A, Söderberg, S, Kirschbaum, C, Murphy, L, Eliasson, M, Ebrahim, S, Davey Smith, G, Olsson, T, Sattar, N, Lawlor, D A, Timpson, N J, Reynolds, R M & Walker, B R 2019, ' Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies ', European Journal of Endocrinology, vol. 181, no. 4 . https://doi.org/10.1530/EJE-19-0161
European Journal of Endocrinology
Crawford, A A, Söderberg, S, Kirschbaum, C, Murphy, L, Eliasson, M, Ebrahim, S, Davey Smith, G, Olsson, T, Sattar, N, Lawlor, D A, Timpson, N J, Reynolds, R M & Walker, B R 2019, ' Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies ', European Journal of Endocrinology, vol. 181, no. 4 . https://doi.org/10.1530/EJE-19-0161
Objective The identification of new causal risk factors has the potential to improve cardiovascular disease (CVD) risk prediction and the development of new treatments to reduce CVD deaths. In the general population, we sought to determine whether co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d37d7a3099cf2ee43fea9585ce10fd34
https://research-information.bris.ac.uk/en/publications/6a1c0aed-3381-4122-a479-6dc317ca0846
https://research-information.bris.ac.uk/en/publications/6a1c0aed-3381-4122-a479-6dc317ca0846
Autor:
Andy, Boyd, Richard, Thomas, Anna L, Hansell, John, Gulliver, Lucy Mary, Hicks, Rebecca, Griggs, Joshua, Vande Hey, Caroline M, Taylor, Tim, Morris, Jean, Golding, Rita, Doerner, Daniela, Fecht, John, Henderson, Debbie A, Lawlor, Nicholas J, Timpson, John, Macleod
Publikováno v:
International Journal of Epidemiology
Autor:
Pasi Soininen, Antti J. Kangas, Nicholas J. Timpson, Fotios Drenos, Caroline Dale, Debbie A Lawlor, Mika Ala-Korpela, Johannes Kettunen, Peter Würtz, Juan-Pablo Casas, Tom R. Gaunt, George Davey Smith
Publikováno v:
Drenos, F, Davey Smith, G, Ala-Korpela, M, Kettunen, J, Würtz, P, Soininen, P, Kangas, A J, Dale, C, Lawlor, D, Gaunt, T, Casas, J-P & Timpson, N 2016, ' Metabolic characterisation of a rare genetic variation within APOC3 and its lipoprotein lipase independent effects ', Circulation: Cardiovascular Genetics, vol. 9, no. 3, pp. 231-239 . https://doi.org/10.1161/CIRCGENETICS.115.001302
Circulation. Cardiovascular Genetics
Circulation. Cardiovascular Genetics
Supplemental Digital Content is available in the text.
Background— Plasma triglyceride levels have been implicated in atherosclerosis and coronary heart disease. Apolipoprotein C-III (APOC3) plays a key role in the hydrolysis of triglyceride-r
Background— Plasma triglyceride levels have been implicated in atherosclerosis and coronary heart disease. Apolipoprotein C-III (APOC3) plays a key role in the hydrolysis of triglyceride-r
Autor:
Dietmar Fernández-Orth, Nicholas J. Timpson, George Dedoussis, Beate St Pourcain, George Davey Smith, Chin Yang Shapland, Tim J Cole, Andrew P. Jackson, Valentina Iotchkova, Jordi Sunyer, Caroline Hayward, Eleftheria Zeggini, Josine L. Min, Fernando Rivadeneira, Simon E. Fisher, Carolina Medina-Gomez, Tarunveer S. Ahluwalia, Ioanna Tachmazidou, Janine F. Felix, Veronique Vitart, Jennifer Huffmann, James F. Wilson, Mònica Guxens, Bram P. Prins, Martine Vrijheid, Hans Bisgaard, Simon Haworth, Craig E. Pennell, Lærke Sass, Vincent W. V. Jaddoe, Louise Cleal, Klaus Bønnelykke, Paul R. H. J. Timmers, Klaudia Walter, Carol A. Wang
Publikováno v:
Nature Communications
Cranial growth and development is a complex process which affects the closely related traits of head circumference (HC) and intracranial volume (ICV). The underlying genetic influences shaping these traits during the transition from childhood to adul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30a8075efec6046758b03c3ee273b3dc