Zobrazeno 1 - 9
of 9
pro vyhledávání: '"544"'
Autor:
Yeon-Mok Oh, Hyoung-Kyu Yoon, Chin Kook Rhee, Yeun-Jun Chung, Seung-Hyun Jung, Tae-Min Kim, Hae-Jin Hu, Seon-Hee Yim, Seung-Hoon Shin, Sang Do Lee
Publikováno v:
COPD: Journal of Chronic Obstructive Pulmonary Disease. 11:652-658
Despite extensive effort, only a few chronic obstructive pulmonary disease (COPD)-associated genes have been suggested, indicating that there must be additional risk-associated loci. Here we aimed to identify additional COPD-associated SNPs and to ex
Autor:
Robert S. Sandler, Joseph A. Galanko, Samuel Antwi, Lesley M. Butler, Jennifer J. Hu, Temitope O. Keku, Susan E. Steck
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 762:24-31
Purpose Much of the DNA damage from colon cancer-related carcinogens, including heterocyclic amines (HCA) and polycyclic aromatic hydrocarbons (PAH) from red meat cooked at high temperature, are repaired by the nucleotide excision repair (NER) pathwa
Publikováno v:
Irish Journal of Medical Science (1971 -). 183:439-448
Oxysterol binding protein-related protein 9 (ORP9) may be related to the pathogenesis of cerebral infarction since it is closely related with glucose and lipid metabolism. The present study was designed to investigate the genetic relationship between
Autor:
Yingze Zhang, Joseph Scuirba, Fernando J. Martinez, Karl Kossen, Pirro G. Hysi, Brenda Juan-Guardela, MeiLan K. Han, Yong Huang, Carlos Flores, Mathew Barber, Shwu Fan Ma, Joe G.N. Garcia, Rekha Vij, Thomas J. Richards, Michael S. Wade, Steven M. Broderick, Naftali Kaminski, Imre Noth, Scott D. Seiwert, Jason D. Christie, Dan L. Nicolae
Publikováno v:
The Lancet Respiratory Medicine. 1:309-317
Summary Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease that probably involves several genetic loci. Several rare genetic variants and one common single nucleotide polymorphism (SNP) of MUC5B have been associated with the dise
Autor:
Xingqiu Zhao, Mark S. Silverberg, Anne M. Griffiths, Aleixo M. Muise, Victorien M. Wolters, Wei Xu, Thomas D. Walters
Publikováno v:
Human Immunology. 72:592-597
Various genes that may influence the intestinal barrier have been identified, including MAGI2, PARD3, and MYO9B. These genes are associated with inflammatory bowel disease (IBD) in several European studies. A total of 2,049 individuals (656 Crohn's d
Autor:
Polat Dura, Rene H. M. te Morsche, Jody Salomon, Wilbert H.M. Peters, Ben J.M. Witteman, Hennie M.J. Roelofs, Jennie Ong, Martin Lacko
Publikováno v:
PLoS One, 9, 3
PLoS ONE
PLOS ONE, 9(3):e90916. Public Library of Science
PLoS ONE, Vol 9, Iss 3, p e90916 (2014)
PLoS One, 9
PLoS ONE
PLOS ONE, 9(3):e90916. Public Library of Science
PLoS ONE, Vol 9, Iss 3, p e90916 (2014)
PLoS One, 9
Contains fulltext : 136543.pdf (Publisher’s version ) (Open Access) INTRODUCTION: Numerous factors influence the development of gastrointestinal (GI) cancer. The insulin-like growth factor (IGF) axis plays a role in embryonic and postnatal growth a
Autor:
Jeremiasz M. Jagiella, Steven M. Greenberg, Lynelle Cortellini, David A. Bennett, K. Schwab, B. B. Worrall, Jonathan Rosand, Joshua M. Shulman, Jörg Schneider, Alessandro Biffi, Scott Silliman, Alison M. Ayres, James F. Meschia, Agnieszka Slowik, P. L. De Jager, Magdy Selim, Devin L. Brown
Objective: Accumulated evidence suggests that a variant within the CR1 gene (single nucleotide polymorphism rs6656401), known to increase risk for Alzheimer disease (AD), influences β-amyloid (Aβ) deposition in brain tissue. Given the biologic over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0fa0fd6ef78ddba44ae3515fef89204
https://europepmc.org/articles/PMC3280047/
https://europepmc.org/articles/PMC3280047/
Publikováno v:
BMC Medical Genetics, Vol 9, Iss 1, p 4 (2008)
BMC Medical Genetics
BMC Medical Genetics
Background FTO is a gene located in chromosome region 16q12.2. Recently two studies have found associations of several single nucleotide polymorphisms (SNPs) in FTO with body mass index (BMI) and obesity, particularly rs1421085, rs17817449, and rs993
Autor:
Peter H. St. George-Hyslop, Fadel Tissir, Lindsay A. Farrer, Mahdi Ghani, Paul E. Fraser, Richard Mayeux, Jean Pierre Brion, Rong Cheng, Satyabrata Kar, André M. Goffinet, Badri N. Vardarajan, Nathalie Daude, Clinton T. Baldwin, Joseph H. Lee, David Westaway, Kunie Ando, Mark W. Logue, David Vergote, Beipei Shi, Jing Yang, Ekaterina Rogaeva
Publikováno v:
Molecular Neurodegeneration
Molecular Neurodegeneration, 8 (1
Molecular Neurodegeneration, Vol. 8, no. 10 (15 février 2013)
Molecular Neurodegeneration, 8 (1
Molecular Neurodegeneration, Vol. 8, no. 10 (15 février 2013)
BACKGROUND: P73 belongs to the p53 family of cell survival regulators with the corresponding locus Trp73 producing the N-terminally distinct isoforms, TAp73 and DeltaNp73. Recently, two studies have implicated the murine Trp73 in the modulation in ph