Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Cornelia Liedtke"'
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Autor:
A. Kohls, Hans-Peter Fischer, Ronald E. Kates, Matthias Christgen, Michael Braun, T. Reimer, Hans Heinrich Kreipe, Nadia Harbeck, Jochem Potenberg, Katja Krauss, E-M. Grischke, Andrea Stefek, Helmut Forstbauer, O Gluz, Doris Augustin, Ulrike Nitz, Claudia Schumacher, Johannes Schumacher, Cornelia Liedtke, Sherko Kuemmel, Rachel Wuerstlein
Publikováno v:
Annals of Oncology. 28:2768-2772
Response rates in HER2-overexpressing EBC treated with neoadjuvant chemotherapy and trastuzumab (T) have been improved by addition of pertuzumab (P). The prospective, phase II, neoadjuvant WSG-ADAPT HER2+/HR- trial assessed whether patients with stro
Autor:
Rachel Wuerstlein, Michael J. Clemens, Ulrike Nitz, Daniel Hofmann, Bahriye Aktas, Ronald E. Kates, F Lorenz-Salehi, V. Heyl, M Kusche, Toralf Reimer, Hans Kreipe, Stefan Kraemer, Steven Shak, Oleg Gluz, Marianne Just, Cornelia Liedtke, Sherko Kuemmel, Nadia Harbeck, Matthias Christgen, Tom Degenhardt, Christer Svedman
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 34(20)
Purpose The 21-gene Recurrence Score (RS) assay is a validated prognostic/predictive tool in early hormone receptor–positive breast cancer (BC); however, only a few prospective outcome results have been available so far. In the phase III PlanB tria
Autor:
Dirk Metzler, Regine Gätje, Jing Wang, Eugen Ruckhäberle, Thomas Karn, Achim Rody, Lajos Pusztai, Uwe Holtrich, Christine Solbach, Marcus Schmidt, A. Ahr, Manfred Kaufmann, Kevin R. Coombes, Cornelia Liedtke, Volkmar Müller, Lars Hanker
Publikováno v:
European Journal of Cancer. 48:12-23
Background Molecular markers displaying bimodal expression distribution can reveal distinct disease subsets and may serve as prognostic or predictive markers or represent therapeutic targets. Oestrogen (ER) and human epidermal growth factor receptor
Autor:
Funda Meric-Bernstam, Wendy A. Woodward, Kristine Broglio, Ludwig Kiesel, Richard L. Theriault, Cornelia Liedtke, S. W. Kau, William Fraser Symmans, Limin Hsu, Stacy L. Moulder, Lajos Pusztai, Gabriel N. Hortobagyi, A. M. Gonzalez-Angulo, Constance Albarracin
Publikováno v:
Annals of Oncology. 20:1953-1958
Background: We evaluated discordance in expression measurements for estrogen receptor (ER), progesterone receptor (PR), and HER2 between primary and recurrent tumors in patients with recurrent breast cancer and its effect on prognosis. Methods: A tot
Autor:
W. Fraser Symmans, Kai Yan, Luca Cardone, Luis J Barajas Figureoa, Gabriel N. Hortobagyi, Vicente Valero, Rebekah Hubbard, Attila Tordai, Cornelia Liedtke, Eduardo A. Souchon, Henry L. Gomez, Lajos Pusztai, Alberto Bardelli
Publikováno v:
Breast Cancer Research : BCR
Introduction In vitro evidence suggests that PIK3CA (phosphatidylinositol 3-kinase, catalytic, alpha polypeptide) activation may be associated with altered chemotherapy sensitivity in cancer. Methods Tumor DNA from 140 patients with stage II–III br