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Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Publikováno v:
Journal of Clinical Oncology. 41:1331-1338
PURPOSE Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the traditional ligand-binding assay (LBA). The purpose
Autor:
Shigeru Hayashi, Kenji Sakai, Takayuki Nojima, Masanao Mohri, Makoto Mori, Masahito Yamada, Katsuhiko Saito, Keitaro Matsubara
Publikováno v:
Internal Medicine. 61:1903-1906
We herein report a 73-year-old man with isolated hypertrophic pachymeningitis (HP) showing serological and pathological characteristics of both IgG4-related disorders and granulomatosis with polyangiitis. The patient presented with chronic onset head
Autor:
Hiroshi Ishii, Yusuke Ueda, Takuto Miyamura, Yuji Yoshida, Hisako Kushima, Mitsuharu Ueda, Takato Ikeda, Seiji Haraoka, Yoshiaki Kinoshita
Publikováno v:
Internal Medicine. 61:877-881
Amyloidosis is a rare disease characterized by the deposition of abnormal proteins in extracellular tissues. We herein report a case with instructive radiologic features of nodular pulmonary amyloidosis associated with Sjögren's syndrome. A 67-year-
Publikováno v:
Internal Medicine. 61:729-733
A 77-year-old woman presented with systemic lymphadenopathy and bilateral pleural effusion. Angioimmunoblastic T-cell lymphoma (AITL) was diagnosed based on the results of a lymph node biopsy. AITL cells expressed the aberrant antigen of CD56. The bi
Autor:
Eiji Isozaki, Tomoya Kawazoe, Takeshi Mizuguchi, Akihiro Kawata, Ichizo Nishino, Naomichi Matsumoto, Yuichi Goto, Shinsuke Tobisawa, Hiroshi Yoshihashi, Takashi Komori, Naohiro Egawa, Kazuhito Miyamoto, Akinori Uruha, Keizo Sugaya
Publikováno v:
Internal Medicine. 61:547-552
We herein report a case of myoclonic epilepsy with ragged-red fibers (MERRF) harboring a novel variant in mitochondrial cysteine transfer RNA (MT-TC). A 68-year-old woman presented with progressive myoclonic epilepsy with optic atrophy and peripheral
Autor:
Masato Kono, Dai Hashimoto, Akari Tsutsumi, Hidenori Nakamura, Noriyuki Enomoto, Takafumi Suda, Mineo Katsumata, Yutaro Nakamura, Masayuki Watanuki, Kenichiro Takeda, Yoshihiro Miki, Yuiko Oshima, Yasutaka Mochizuka, Hideki Miwa, Ryutaro Hirama
Publikováno v:
Internal Medicine. 61:395-400
A 67-year-old man was admitted to our hospital with cough and fatigue. He had had long-term exposure to silica due to cement processing. Chest computed tomography showed bilateral centrilobular nodules, and hilar and mediastinal lymphadenopathy with
Autor:
Hakim Khettab, Agnieszka Latosinska, Harald Mischak, Jan A. Staessen, Alessandra Bacca, Christophe Beauloye, Stefano Taddei, Pierre Boutouyrie, Miikka Vikkula, Alexandre Persu, Rosa Maria Bruno, Marco Pappaccogli, Laurent Toubiana
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Hypertension (Dallas, Tex. : 1979), 2021, pp.HYPERTENSIONAHA12118
Hypertension (Dallas, Tex. : 1979), Vol. 79, no.1, p. 93-103 (2022)
Hypertension (Dallas, Tex. : 1979), 2021, pp.HYPERTENSIONAHA12118
Hypertension (Dallas, Tex. : 1979), Vol. 79, no.1, p. 93-103 (2022)
Fibromuscular dysplasia (FMD), a nonatherosclerotic, noninflammatory disease of medium-sized arteries, is an underdiagnosed disease. We investigated the urinary proteome and developed a classifier for discrimination of FMD from healthy controls and o
Autor:
Masahiro Tsutsumi, T. Koga, Aya Kawaguchi, Hiroaki Ida, Yumi Harada, Makiko Hayashi, Shinjiro Kaieda, Jun Akiba, Tomoaki Hoshino
Publikováno v:
Internal Medicine
We herein report an unusual case of granulomatosis with polyangiitis (GPA) in a 65-year-old man in whom relapsed disease manifested as an anterior cheek nodule. Magnetic resonance imaging indicated the differential diagnoses of the subcutaneous nodul
Autor:
Takashi Endo, Yosuke Kobayashi, Hirohisa Harada, Masanori Odaira, Seiichi Tamai, Haruka Yagishita, Fumiki Toriumi, Shigemichi Hirose, Shinsuke Funakoshi, Eisuke Shiomi, Yoshie Kadota
Publikováno v:
Clinical Journal of Gastroenterology. 15:185-191
A 70-year-old Japanese woman who was treated for interstitial pneumonia (IP) with steroid therapy developed cholecystitis. A serial computed-tomography (CT) imaging showed irregular thickness of the fundus wall of the gallbladder and two rapidly enla