Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michel Laviolette"'
Autor:
Michel Laviolette, Isabelle Dubuc, Younes Zaid, Nicolas Flamand, Louis Flamand, Olivier Flamand, Anne Sophie Archambault, Étienne Doré, Eric Boilard
Publikováno v:
The Journal of Allergy and Clinical Immunology
Background Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection can lead to a variety of clinical outcomes ranging from the absence of symptoms to severe acute respiratory disease and ultimately death. A feature of patients with sev
Autor:
Michel Laviolette, Suzanne Maahs, Veronica A. Swystun, Louis-Philippe Boulet, Irvin Mayers, Christopher Carlsten, Philip J. Lowe, Barbro Dahlén, Andrej Skerjanec, Miranda Bowen, Richard Leigh, Linda Hui, Beth E. Davis, Richard M. Watson, Gail M. Gauvreau, Kieran J. Killian, Joanne Milot, Anton Drollmann, Paul M. O'Byrne, J. Mark FitzGerald, Ann-Sofie Lantz, Karin Meiser, Nikolaos Lazarinis, Jonathan P. Arm, Donald W. Cockcroft
Publikováno v:
Journal of Allergy and Clinical Immunology. 138:1051-1059
Background Omalizumab is an established anti-IgE therapy for the treatment of allergic diseases that prevents IgE from binding to its receptor. QGE031 is an investigational anti-IgE antibody that binds IgE with higher affinity than omalizumab. Object
Publikováno v:
Clinical Epigenetics
Allergic rhinitis is a common chronic disorder characterized by immunoglobulin E-mediated inflammation. To identify new genes associated with this trait, we performed genome- and epigenome-wide association studies and linked marginally significant Cp
Autor:
Ian D, Pavord, Neil C, Thomson, Robert M, Niven, Paul A, Corris, Kian Fan, Chung, Gerard, Cox, Brian, Armstrong, Narinder S, Shargill, Michel, Laviolette, Arthur S, Slutsky
Publikováno v:
Annals of Allergy, Asthma & Immunology. 111:402-407
Background: Patients with severe refractory asthma treated with bronchial thermoplasty (BT), a bronchoscopic procedure that improves asthma control by reducing excess airway smooth muscle, were followed up for 5 years to evaluate long-term safety of
Autor:
Claudine Ferland, Michel Laviolette, Francis Davoine, Sophie Lavigne, Marie-Eve Boulay, Jamila Chakir
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:463-469
Background: Blood eosinophils have mRNA for FcγRIIIB (CD16) but no or minimal spontaneous CD16 expression. Because IFN-γ and chemotactic factors induce eosinophil CD16 expression in vitro, we postulated that blood eosinophils could express CD16. Ob
Autor:
Yutaka Nakamura, Shigeo Muro, Qutayba Hamid, Ron Olivenstein, Michel Laviolette, Pota Christodoulopoulos, Lisa Cameron, Catherine Lemière, Louis-Philippe Boulet, Mario Dugas
Publikováno v:
Journal of Allergy and Clinical Immunology. 107:586-591
The expression of IL-4 and IL-5 is increased in patients with atopic asthma compared with control subjects and correlates with indices of pulmonary function. In nonatopic asthma the expression of IL-4, unlike IL-5, fails to correlate with pulmonary f
Autor:
Catherine Laprise, Qutayba Hamid, Jamila Chakir, Michel Laviolette, Louis-Philippe Boulet, Anne-Marie Madore, Elyse Y. Bissonnette, Celine Bergeron, Karim Maghni
Publikováno v:
The Journal of asthma : official journal of the Association for the Care of Asthma. 51(2)
Given the large phenotypic diversity of asthma, our aim was to characterize molecular profiles related to asthma severity using selected remodeling biomarkers in induced sputum.Induced sputum from healthy controls, patients with mild to moderate asth
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 159:1830-1834
To verify whether alveolar macrophages (AM) of patients with hypersensitivity pneumonitis (HP) increase their antigen-presenting capacity by upregulating the expression of B7 costimulatory molecules (CD80, CD86), and whether a viral infection enhance
Autor:
Mario, Castro, Adalberto, Rubin, Michel, Laviolette, Nicola A, Hanania, Brian, Armstrong, Gerard, Cox, B, Armstrong
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 107(1)
BACKGROUND: Bronchial thermoplasty (BT) has been demonstrated to be safe and effective in the treatment of severe persistent asthma out to at least 1 year. Preclinical studies have demonstrated that the reduction in airway smooth muscle after bronchi
Autor:
Neil Barnes, Frederick E. Hargreave, Ian D. Pavord, Helen Tate, Debbie Parker, David Allen, Michel Laviolette, Brian J. O'Connor, P. Flood-Page, Paul A. Corris
Publikováno v:
Respiratory medicine. 101(8)
SummaryMany patients with asthma remain symptomatic with impaired airway function on inhaled steroids. This study investigates the relationship between the clinical effect seen in response to additional treatment and the effect on airway inflammatory