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Autor:
Daniel Moj, Nicola Ammer, Babette Aicher, Jan-Georg Wojtyniak, Thorsten Lehr, Michael Teifel, Herbert Sindermann, Hannah Britz, Nina Hanke
Zoptarelin doxorubicin is a fusion molecule of the chemotherapeutic doxorubicin and a luteinizing hormone-releasing hormone receptor (LHRHR) agonist, designed for drug targeting to LHRHR positive tumors. The aim of this study was to establish a physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c5e9a18956370d7aca5ee1061fd910
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 37:556-564
Purpose: To investigate the influence of benzalkonium chloride (BAK) on ocular surface disease (OSD) in glaucoma patients receiving ocular-hypotensive agent. Methods: Patients were randomized to re...
Autor:
Ali Unlu, Gulsum Abusoglu, Fatma Humeyra Yerlikaya, Dilek Tezcan, Duygu Eryavuz Onmaz, Sema Yilmaz, Mustafa Onmaz, Sedat Abusoglu
Publikováno v:
Inflammopharmacology
Hydroxychloroquine has attracted attention in the treatment of COVID-19. Many conflicting findings have been reported regarding the efficacy and safety of this drug, which has been used safely in the rheumatological diseases for years. However, these
Autor:
Nancy Chan, Jiuping Ji, Antoinette R. Tan, Janice M. Mehnert, Alice P. Chen, Jan H. Beumer, Mansi Shah, Joseph Aisner, Murugesan Gounder, Jyoti Malhotra, Rebecca A. Moss, Yong Lin, Brian F. Kiesel, Hongxia Lin, Mark N. Stein, Michael P. Kane
Publikováno v:
Cancer Chemother Pharmacol
Purpose Veliparib (V), an oral poly(ADP-ribose) polymerase (PARP) inhibitor, potentiates effects of alkylating agents and topoisomerase inhibitors in preclinical tumor models. We conducted a phase I trial of V with iv cyclophosphamide (C) and V plus
Autor:
Raphael Teipel, Susanne Quick, Stephan Richter, Holger Knoth, Theresa Kretschmann, Frank Kroschinsky, Christoph Röllig, Ekaterina Balaian, Nael Alakel, Martin Bornhäuser, Sandra Heuschkel, Malte von Bonin, Simone von Bonin
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose High-dose methotrexate (HDMTX)-associated acute kidney injury with delayed MTX clearance has been linked to an excess in MTX-induced toxicities. Glucarpidase is a recombinant enzyme that rapidly hydrolyzes MTX into non-toxic metabolites. The
Autor:
Leyla Hazar, Esra Vural
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 37:430-437
WOS:000648054200001 PMID: 33961524 Purpose: To evaluate inflammation biomarkers in diabetic macular edema (DME) treated with intravitreal dexamethasone implant (Ozurdex(R)). Methods: This retrospective single-center study investigated 64 eyes of 64 p
Autor:
Aurélien Emmanuel Martinez, Martin Siegemund, Emmanuelle Landmann, Catia Marzolini, Anne Leuppi-Taegtmeyer, Michael Dickenmann, Manuel Battegay, Nadine Cueni, Alexa Hollinger
Publikováno v:
AIDS Research and Therapy, Vol 18, Iss 1, Pp 1-5 (2021)
AIDS Research and Therapy
AIDS Research and Therapy
Background We report a case of sudden, lethal metabolic acidosis in a 70-year-old man on long-term nucleoside reverse transcriptase inhibitor (NRTI) -based antiretroviral therapy (ART) who had developed atypical necrotizing fasciitis 1 month after ki
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 10, Iss 9, Pp 1071-1080 (2021)
CPT: Pharmacometrics & Systems Pharmacology
CPT: Pharmacometrics & Systems Pharmacology
A combination of olanzapine and samidorphan (OLZ/SAM) was recently approved by the US Food and Drug Administration for treatment of patients with schizophrenia or bipolar I disorder. The effects of moderate hepatic impairment on the pharmacokinetics
Autor:
Antonio Asti, Roberta Bottino, Valerio Langella, Domenico Pomponi, Gisella Di Palma, Vincenzo Russo, Claudia Sassone, Egidio Imbalzano, Giulio Maresca
Publikováno v:
Expert Review of Clinical Pharmacology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Purpose: We aimed to investigate the clinical performance of edoxaban for the treatment of pulmonary embolism (PE) in hospitalized COVID-19 patients. Methods: We conducted a retrospective analysis selecting hospitalized patients with COVID-19 admitte
Autor:
Zhijian Liang, Jian Yu, Shihui Xing, Jinsheng Zeng, Weisheng Deng, Jianle Li, Fubing Ouyang, Yicong Chen, Yusheng Zhang, Weixian Huang, Zilin Ou
Publikováno v:
CNS Neuroscience & Therapeutics
Aims The risk of hemoglobin decline induced by low‐dose aspirin in glucose‐6‐phosphate dehydrogenase (G6PD) deficiency remains unknown, and its influence on stroke outcome remains to be investigated. This study aimed to evaluate the effect of G