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Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-7 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
This study (ORIENT-4) aimed to assess the efficacy and safety of sintilimab, a humanized anti-PD-1 antibody, in patients with relapsed/refractory extranodal NK/T cell lymphoma (r/r ENKTL). ORIENT-4 is a multicenter, single-arm, phase 2 clinical trial
Autor:
Mireia Martín-Satué, Marçal Pastor-Anglada, Loreto Boix, Clara Boces-Pascual, Aida Mata-Ventosa, Meritxell Gironella, Sandra Pérez-Torras
Publikováno v:
Cellular and Molecular Life Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Graphic abstract High-affinity uptake of natural nucleosides as well as nucleoside derivatives used in anticancer therapies is mediated by human concentrative nucleoside transporters (hCNTs). hCNT1, the hCNT family member that specifically transports
Autor:
Xiaoyu Wang, Xian Zhang, Linzhi Gao, Xiaoya Luo, Jun Lyu, Dong Zhang, Xuesong Gao, Yuan Shen, Shaolie Zheng, Guifang Jiang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
Purpose Aims to compare the prognostic performance of the number of positive lymph nodes (PLNN), lymph node ratio (LNR) and log odds of metastatic lymph nodes (LODDS) and establish a prognostic nomogram to predict overall survival (OS) rate for patie
Autor:
Hao Wang, Qiaohua Xie, Cong Cheng, Peng Wang, Liping Lei, ShouZi Hu, Guofang Liu, Huabang Zhou, YouShun Liu, Heping Hu
Publikováno v:
Bulletin du Cancer. 108:931-939
Summary Background Both modified Child-Pugh (MCP) and Albumin-bilirubin (ALBI) grade were reported that simpler, more objective and evidence-based alternative to the Child-Pugh (CP) class for assessing liver function. Aims To investigate whether the
Autor:
Fei Ma, Yanxia Sun, Qing Li, Peng Yuan, Shanshan Chen, Jiayu Wang, Yang Luo, Ying Fan, Pei Yu, Binghe Xu, Yiqun Han, Ruigang Cai, Qiao Li, Pin Zhang
Publikováno v:
Clinical Breast Cancer. 21:e497-e505
Different clinicopathologic characteristics could contribute to inconsistent prognoses of small breast neoplasms (T1a/T1b). This study was done to conduct a retrospective analysis and establish a clinical prediction model to predict individual surviv
Autor:
Feiqian Wang, Kazushi Numata, Hiroyuki Fukuda, Yuichirou Tsurugai, Katsuaki Ogushi, Shin Maeda, Hiromi Nihonmatsu, Atsuya Takeda, Makoto Chuma, Koji Hara
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-12 (2021)
BMC Cancer
BMC Cancer
Background In clinical practice, many hepatocellular carcinoma (HCC) patients in Barcelona Clinical Liver Cancer (BCLC) stage A4–B1 cannot receive the curative treatments of liver transplantation, resection, and radiofrequency ablation (RFA), which
Autor:
Ya-Wen Ho, Chang-Hsien Lu, Chen-Kan Tseng, Wen-Chi Chou, Yung-Hsin Huang, Chieh Yang, Yu-Shin Hung, Ngan-Ming Tsang, Cheng-Chou Lai, Shun-Wen Hsueh, Pei-Hung Chang, Chia-Yen Hung, Ming-Mo Ho, Kun-Yun Yeh, Yu-Ching Lin
Publikováno v:
Anticancer Research. 41:5213-5222
BACKGROUND/AIM The clinical significance of frailty status on treatment outcome in patients with esophageal cancer (EC) has been seldom explored. This study aimed to evaluate the impact of pretreatment frailty on treatment-related toxicity and surviv
Publikováno v:
Anticancer Research. 41:5001-5006
Background/aim To describe clinical features, radiotherapy (RT), and symptom outcomes in cancer patients with cranial nerve palsies associated with clival metastases. Patients and methods This is a retrospective review of patients with primary metast
Autor:
Teruhisa Sakamoto, Yoichiro Tada, Shuichi Takano, Wataru Miyauchi, Kyoichi Kihara, Kazushi Hara, Toshimichi Hasegawa, Yoshiaki Matsumi, Ken Sugesawa, Manabu Yamamoto, Yoshiyuki Fujiwara, Yuji Nakayama, Akimitsu Tanio, Chihiro Uejima
Publikováno v:
Anticancer Research. 41:4857-4865
Background/aim M1 macrophages have antitumour effects, while M2 macrophages promote tumour proliferation and invasion. The clinical significance of the M2-specific marker CD204 has not been elucidated in colorectal cancer (CRC). We investigated the p
Autor:
Hideo Baba, Taishi Yamane, Shinya Shimada, Kei Horino, Daisuke Izumi, Chika Shirakami, Keisuke Morita, Satoshi Ikeshima, Shotaro Kinoshita
Publikováno v:
Anticancer Research. 41:5223-5229
AIM The aim of the current study was to investigate whether the artery-first approach (AFA) improved surgical outcomes of pancreaticoduodenectomy (PD) at our non-high-volume center. PATIENTS AND METHODS We retrospectively reviewed data on 121 consecu