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Publikováno v:
Cancer Medicine, Vol 10, Iss 23, Pp 8483-8496 (2021)
Cancer Medicine
Cancer Medicine
Background The optimal treatment for elderly patients with esophageal cancer (EC) remains controversial. In the present study, we aimed to investigate whether elderly patients with stage II–III EC could benefit from trimodal therapy. Methods The se
Autor:
Mariko Tabata, Yutaka Enomoto, Yusuke Sato, Masahiro Hikatsu, Hideyo Miyazaki, Yukio Yamada, Taro Murata, Yasushi Kondo, Tohru Nakagawa, Taketo Kawai, Jimpei Miyakawa, Haruki Kume, Satoru Taguchi, Akihiko Matsumoto, Akihiro Naito, Hiroaki Nishimatsu, Tomoyuki Kaneko, Takumi Takeuchi, Yoshinori Tanaka, Motofumi Suzuki
Publikováno v:
Japanese Journal of Clinical Oncology. 51:1577-1586
Purpose Renal function is frequently impaired in the patients with upper tract urothelial carcinoma. We aimed to evaluate the impact of renal function and its change after surgery on survival rates in patients with upper tract urothelial carcinoma af
Autor:
Aliyah Pabani, Benjamin W. Ewanchuk, Tina Cheng, Siddhartha Goutam, Isabelle A. Vallerand, Daniel Y.C. Heng, Igor Stukalin, Daniel E. Meyers, Michael Sander, Don Morris
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 8, Pp 2618-2626 (2021)
Cancer Medicine, Vol 10, Iss 8, Pp 2618-2626 (2021)
Background Metastatic uveal melanoma (MUM) is associated with poor survival and inferior response to immune checkpoint inhibitor (ICI) therapy when compared with metastatic cutaneous melanoma. Currently, prognostic biomarkers are lacking to guide tre
Publikováno v:
Cancer Medicine, Vol 10, Iss 3, Pp 1034-1042 (2021)
Cancer Medicine
Cancer Medicine
Background Mismatch repair (MMR) system has been implicated in the response of mammalian cells to ionizing radiation and DNA damaging agents. We investigated the value of the MMR system in predicting response to adjuvant therapy in endometrial cancer
Publikováno v:
Cancer Medicine, Vol 10, Iss 3, Pp 914-922 (2021)
Cancer Medicine
Cancer Medicine
The previous retrospective study suggested that dosing vitamin K may enhance the anticancer action of sorafenib against hepatocellular carcinoma. To confirm it, we performed a phase II, randomized, open‐label study. Patients with hepatocellular car
Autor:
Nazli Dizman, Bernadett Szabados, Sumanta K. Pal, Frede Donskov, Toni K. Choueiri, Guillermo Velasco, Benoit Beuselinck, Chun Loo Gan, Daniel Y.C. Heng, Aly-Khan A. Lalani, Ulka N. Vaishampayan, J. Connor Wells, Aaron R. Hansen, Nityam Rathi, Georg A. Bjarnason, Ben Tran, Flora Yan, Shaan Dudani, Jae-Lyun Lee, Mathushan Subasri
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 4, Pp 1212-1221 (2021)
Gan, C L, Dudani, S, Wells, J C, Donskov, F, Pal, S K, Dizman, N, Rathi, N, Beuselinck, B, Yan, F, Lalani, A K A, Hansen, A, Szabados, B, de Velasco, G, Tran, B, Lee, J L, Vaishampayan, U N, Bjarnason, G A, Subasri, M, Choueiri, T K & Heng, D Y C 2021, ' Cabozantinib real-world effectiveness in the first-through fourth-line settings for the treatment of metastatic renal cell carcinoma : Results from the International Metastatic Renal Cell Carcinoma Database Consortium ', Cancer Medicine, vol. 10, no. 4, pp. 1212-1221 . https://doi.org/10.1002/cam4.3717
Cancer Medicine, Vol 10, Iss 4, Pp 1212-1221 (2021)
Gan, C L, Dudani, S, Wells, J C, Donskov, F, Pal, S K, Dizman, N, Rathi, N, Beuselinck, B, Yan, F, Lalani, A K A, Hansen, A, Szabados, B, de Velasco, G, Tran, B, Lee, J L, Vaishampayan, U N, Bjarnason, G A, Subasri, M, Choueiri, T K & Heng, D Y C 2021, ' Cabozantinib real-world effectiveness in the first-through fourth-line settings for the treatment of metastatic renal cell carcinoma : Results from the International Metastatic Renal Cell Carcinoma Database Consortium ', Cancer Medicine, vol. 10, no. 4, pp. 1212-1221 . https://doi.org/10.1002/cam4.3717
Background Cabozantinib is approved for metastatic renal cell carcinoma (mRCC) based on the METEOR and CABOSUN trials. However, real‐world effectiveness and dosing patterns of cabozantinib are not well characterized. Methods Patients with mRCC trea
Autor:
Yuichiro Tsurugai, Tomoki Kimura, Yohei Oku, Atsuya Takeda, Hideharu Miura, Kazunari Hioki, Yoshiko Doi, Reo Kawano, Yasushi Nagata
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 108:1265-1275
Purpose Through this multi-institutional study, we aimed to retrospectively evaluate the safety and efficacy of repeated stereotactic body radiation therapy (SBRT) for intrahepatic recurrent hepatocellular carcinoma (HCC). Methods and Materials Betwe
Autor:
Samantha LoRusso, Qiuhong Zhao, Jason Prosek, Katherine Pfund, Srinivas Devarakonda, Ashley E. Rosko, Patrick Elder, Elyse Redder, Ajay Vallakati, Jordan Bittengle, Yvonne A. Efebera, Courtney M. Campbell, Maria Chaudhry, Salem Almaani, Nidhi Sharma, Samir V. Parikh, Naresh Bumma, Don M. Benson, Abdullah Khan, Rami Kahwash, Nita Williams, Miriam Freimer, Michael Ozga
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 3, Pp 965-973 (2021)
Cancer Medicine, Vol 10, Iss 3, Pp 965-973 (2021)
Background Systemic light chain (AL) amyloidosis is a clonal plasma‐cell neoplasm that carries a poor prognosis. Although AL amyloidosis and Multiple Myeloma (MM) can co‐exist and share various cytogenetic chromosomal abnormalities, little is kno
Publikováno v:
Cancer Medicine
Background Smoking is a well‐known risk factor for colorectal cancer incidence; however, the effect of smoking before and after cancer diagnosis on mortality has not been addressed well. Thus, we aimed to evaluate the association of prediagnosis an
Publikováno v:
Cancer Medicine
Due to the limited data and research on bladder cancer with distant metastasis, the role of surgery on the primary tumor site in metastatic bladder cancer has been controversial. The aim of this study was to investigate the impact of surgery on patie