Zobrazeno 1 - 10
of 38 677
pro vyhledávání: ''
Autor:
Ulrich Gatzemeier, Michael Boyer, Paolo Paoletti, Salih Emri, Christian Manegold, Claude Denham, Nicholas J. Vogelzang, James J. Rusthoven, James T. Symanowski, Clet Niyikiza, E. Kaukel, Pierre Ruffié
Publikováno v:
Journal of Clinical Oncology. 41:2125-2133
PURPOSE Patients with malignant pleural mesothelioma, a rapidly progressing malignancy with a median survival time of 6 to 9 months, have previously responded poorly to chemotherapy. We conducted a phase III trial to determine whether treatment with
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Publikováno v:
Journal of Clinical Oncology. 41:1331-1338
PURPOSE Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the traditional ligand-binding assay (LBA). The purpose
Publikováno v:
Clinical Breast Cancer. 22:771-780
Considering old age and comorbidities, the actual benefit of chemotherapy in older patients with early triple-negative breast cancer (TNBC) remains uncertain. We aimed to select appropriate patients who could avoid chemotherapy in this population.A t
Autor:
Keita, Kouzu, Hironori, Tsujimoto, Naoyuki, Uehata, Yusuke, Ishibashi, Yoji, Kishi, Hideki, Ueno
Publikováno v:
Anticancer Research. 42:5999-6006
This study aimed to evaluate the prognostic value of modified geriatric nutritional risk index (mGNRI) in patients with unresectable/recurrent esophageal cancer (EC).We included 143 patients aged65 years with unresectable/recurrent EC. The mGNRI was
Autor:
Takahiro Fukushima, Yoshitaka Oyamada, Shinnosuke Ikemura, Shigenari Nukaga, Takashi Inoue, Daisuke Arai, Keiko Ohgino, Aoi Kuroda, Kota Ishioka, Fumio Sakamaki, Yusuke Suzuki, Hideki Terai, Hiroyuki Yasuda, Ichiro Kawada, Koichi Fukunaga, Kenzo Soejima
Publikováno v:
Clinical Lung Cancer. 23:532-541
The optimal treatment for advanced non-small cell lung cancer (NSCLC) in very elderly patients is unclear. We aimed to evaluate their treatment in real-world clinical practice and identify suitable therapy that can improve their prognosis.The medical
Autor:
Adriana Garduño-Alanis, Lizbeth Morales-González, Angélica Ángeles-Llerenas, José Zaim Delgado-Ramírez, Carolina Ortega-Olvera, Gabriela Torres-Mejía
Publikováno v:
Cancer Causes & Control. 33:1355-1361
The delay in the time (in calendar days) from the delivery of mammography results to histopathological breast cancer (BC) diagnosis could be associated with more advanced clinical stages, a worse prognosis and higher mortality. Therefore, we assessed
Autor:
HARUKA YOSHII, KAZUMASA SEKIHARA, YUKA IDETA, SHINTARO NAKAJIMA, IKUMA KATO, MAKIKO OKUBO-SATO, KEI SUGIURA, KENJI MITSUDO, MITOMU KIOI
Publikováno v:
Anticancer Research. 42:3815-3823
SIRT6 is one of seven human sirtuin genes and is known to act as an onco-suppressor gene in colorectal and ovarian cancers, although it is up-regulated in other cancers. Thus, SIRT6 is considered performing both tumor-suppressing and promoting roles.
Publikováno v:
Nutrition and Cancer. 74:3623-3633
This study aimed to quantitatively identify the prognostic and clinicopathological value of the geriatric nutritional risk index (GNRI) in non-small cell lung cancer (NSCLC) through a meta-analysis. The electronic databases PubMed, Web of Science, Em
Autor:
Christian Lang, Felix Egger, Mir Alireza Hoda, Alessandro Saeed Querner, Bence Ferencz, Victor Lungu, Robert Szegedi, Levente Bogyo, Klara Torok, Felicitas Oberndorfer, Thomas Klikovits, Anna Schwendenwein, Kristiina Boettiger, Ferenc Renyi-Vamos, Konrad Hoetzenecker, Karin Schelch, Zsolt Megyesfalvi, Balazs Dome
Publikováno v:
Lung Cancer. 169:40-46
The prognostic value of lymphocyte-to-monocyte ratio (LMR) has already been evaluated in a wide range of malignancies including patients with non-surgically managed small cell lung cancer (SCLC). However, the impact of LMR on survival in surgically t