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Autor:
Qinghua Han, Lindsey A. Barner, Lawrence D. True, Chenyi Mao, Andrew Janowczyk, Pingfu Fu, Robert Serafin, Nicholas P. Reder, Anant Madabhushi, Jonathan T. C. Liu, Can Fahrettin Koyuncu, Patrick Leo, Sarah Hawley, Weisi Xie, Hongyi Huang, Jonathan L. Wright, Gan Gao, Adam K. Glaser, Soyoung Kang, Kevin Bishop, Nadia Postupna, C. Dirk Keene, Joshua C. Vaughan
Publikováno v:
Cancer Res
Prostate cancer treatment planning is largely dependent upon examination of core-needle biopsies. The microscopic architecture of the prostate glands forms the basis for prognostic grading by pathologists. Interpretation of these convoluted three-dim
Publikováno v:
Cancer Biomarkers. 32:271-279
This paper aimed at investigating AS1 expression in prostate cancer (PCa) and its effects on the proliferation and invasion of prostate cancer cells (PCCs). The prostate tissues and the matched adjacent normal prostate tissues excised and preserved d
Autor:
Cristina Magi-Galluzzi, Michael Brooks, Tamer Aboushwareb, Lewis Thomas, Eric A. Klein, Ruixiao Lu, Jianbo Li, Michael Crager, John Abran
Publikováno v:
JCO Precision Oncology
PURPOSE To assess the association between the Oncotype DX Genomic Prostate Score (GPS) result and long-term oncological outcomes following radical prostatectomy (RP). METHODS We evaluated the association of the GPS result assayed from the index lesio
Autor:
Tetsuya Fukumoto, Naoya Sugihara, Kenichi Nishimura, Noriyoshi Miura, Yuki Miyauchi, Ryuta Watanabe, Yuichiro Sawada, Takashi Saika, Keisuke Funaki, Tadahiko Kikugawa, Kanae Koyama, Toshio Kakuda, Terutaka Noda
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 7968-7976 (2021)
Cancer Medicine
Cancer Medicine
Background Patients with very‐high‐risk prostate cancer (VHRPCa) have earlier biochemical recurrences (BCRs) and higher mortality rates. It remains unknown whether extended robot‐assisted laparoscopic prostatectomy (eRALP) without neoadjuvant o
Autor:
Isaac E. Kim, Monish Aron, Thomas L. Jang, Daniel D. Kim, Saum Ghodoussipour, Mark N. Stein, Isaac Yi Kim, David Y. Lee, Marc A. Dall'Era, Eric A. Singer, Sinae Kim
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 7909-7920 (2021)
Cancer Medicine
Cancer Medicine
Since 2004, multiple blockbuster drugs have been approved for men with metastatic prostate cancer. Nevertheless, it has been reported that no improvement in survival was observed between 2004 and 2009. Herein, we have analyzed the SEER database to as
Autor:
Yukio Naya, Kyokusin Hou, Satoko Kojima, Manato Kanesaka, Takahito Suyama, Hiroshi Masuda, Kazuhiro Araki, Ayumi Fujimoto
Publikováno v:
Anticancer Research. 41:4443-4446
BACKGROUND Androgen deprivation therapy (ADT) is one of the most effective treatments for advanced prostate cancer (PCa). However, it has been reported that the use of ADT is significantly associated with an increased risk of acute kidney injury (AKI
Autor:
Alain Bergeron, France-Hélène Joncas, Aerin Park, Clovis Boibessot, Jean-François Pelletier, Paul Toren, Typhaine Gris, Zohra Berrehail
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Within the prostate tumor microenvironment (TME) there are complex multi-faceted and dynamic communication occurring between cancer cells and immune cells. Macrophages are key cells which infiltrate and surround tumor cells and are recognized to sign
Publikováno v:
Molecular Biotechnology. 64:17-24
Prostate cancer (PCa) is the most popular cancer of mankind. Our study aimed to provide the expression and the predictive significance of miR-1273 g-3p in PCa. Moreover, the effects on cell biological activities were also investigated. The relative e
Autor:
Xin Li, Kazutoshi Fujita, Yujiro Hayashi, Osamu Ogawa, Hiroko Kimura, Takayuki Goto, Norio Nonomura, Shusuke Akamatsu, Kenji Nakayama, Takahiro Inoue, Takashi Kobayashi, Koji Shimizu
Publikováno v:
Cancer Science
The altered levels of phospholipids (PLs) and lysophospholipids (LPLs) in prostate cancer (CaP) and benign tissues in our previous findings prompted us to explore PLs and LPLs as potential biomarkers for CaP. Urinary lipidomics has attracted increasi
Publikováno v:
Aging (Albany NY)
Metastatic cancer especially bone metastasis (BM) is the lethal end-stage of castration-resistant prostate cancer (CRPC). To understand the possible molecular mechanisms underlying the development of the distant metastasis is of potential clinical va