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Publikováno v:
Cancer Medicine, Vol 10, Iss 17, Pp 5757-5764 (2021)
Cancer Medicine
Cancer Medicine
Introduction Pulmonary nuclear protein of the testis (NUT) midline carcinoma (NMC) is a aggressive cancer with t (15, 19) translocation. Here we present the clinicopathological characteristics and molecular genetics alterations of primary pulmonary N
Autor:
Yoshihiro Komohara, Toshiyuki Shima, Masayuki Shimoda, Remi Mito, Yusuke Shinchi, Koei Ikeda, Makoto Suzuki, Takuro Sakagami, Eri Matsubara, Yae Kanai, Yukio Fujiwara
Publikováno v:
Pathology International. 71:666-673
CD163 is one of the scavenger receptors expressed on macrophages. However, several immunohistochemical studies have demonstrated that CD163 is also detected on cancer cells, and is associated with a poor prognosis. In the present study, we detected C
Autor:
Yoshihiko Murata, Tomoki Nakagawa, Yunjung Kim, Junko Kano, Masayuki Noguchi, Zeinab Kosibaty, Noriaki Sakamoto
Publikováno v:
Pathology International
The expression of Ras-specific guanine nucleotide-releasing factor 2 (RasGRF2) in lung adenocarcinomas was examined using immunohistochemistry in relation to clinicopathological characteristics and prognosis. In comparison to low expression, high exp
Autor:
Yuqiao Sheng, Feng Li, Jingjing Xu, Shengli Ma, Xiaoping Shang, Yang Yang, Zhihai Qin, Na Wei, Xixi Duan, Jiajia Wan, Rui Xue
Publikováno v:
International Journal of Cancer. 148:1519-1528
To investigate the clinical value of Tie2-expressing monocytes (TEMs) in the early diagnosis of lung cancer and assess its correlation with angiogenesis, a total of 184 patients with non-small cell lung cancer (NSCLC), 101 patients with benign pulmon
Autor:
Yoshiki Murakumo, Naoya Asai, Yukihiro Shiraki, Masahide Takahashi, Liang Weng, Shinji Mii, Kohei Yokoi, Tetsuro Taki, Chen Chen, Atsushi Enomoto
Publikováno v:
Cancer Science
Stromal invasion is considered an important prognostic factor in patients with lung adenocarcinoma. The mechanisms underlying the formation of tumor stroma and stromal invasion have been studied in the lung; however, they are still unclear. CD109 is
Publikováno v:
Cancer Cytopathology. 129:148-155
BACKGROUND Immune checkpoint inhibitor therapy has revolutionized lung adenocarcinoma therapy. Treatment with antibodies against the immune checkpoint molecules programmed death-1 (PD-1) and programmed death-ligand 1 (PD-L1) can induce a durable resp
Autor:
Shinji Sasada, Yuichiro Ohe, Ryuta Fukai, Toshiyuki Nakai, Yuji Matsumoto, Midori Tanaka, Tomoki Nishida, Shun-ichi Watanabe, Noriko Motoi
Publikováno v:
Japanese Journal of Clinical Oncology. 51:271-278
Background Precision medicine in non-small cell lung cancer requires attainment of a sufficient amount of high-quality tumor tissue. Transbronchial cryobiopsy has emerged as a new diagnostic method for non-neoplastic lung disease with a better potent
Autor:
Pekka Taimen, Alhadi Almangush, Hesham Mohamed, Ilmo Leivo, Markku Kallajoki, Heikki Vilhonen, Tarja Laitinen, Katri Orte, Samu Kurki, Yajuvinder Singh, Antti Karlsson, Eva-Maria Talvitie, Lassi J. Liljeroos
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 333-342 (2020)
Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 333-342 (2020)
Objectives: Tumor mutation burden (TMB) is an emerging predictive cancer biomarker. Few studies have addressed the prognostic role of TMB in non-small cell lung carcinoma, with conflicting results. Moreover, the association of TMB with different hist
Autor:
Jinping Lai, Qiuying Shi, Malathy Kapali, Can Cao, Max X. Kong, Koorosh Moezardalan, Ali Azarm
Publikováno v:
Anticancer Research. 40:4401-4404
Background The occurrence of lung adenocarcinoma metastasizing to the pancreas is overall rare and can histologically imitate primary pancreatic ductal carcinoma (PDAC). Case report This is a case report of a 70-year-old female with a history of surg
Autor:
Kazuhiko Shien, Yuta Takahashi, Shinichi Toyooka, Masaomi Yamane, Hiromasa Yamamoto, Susumu Kanazawa, Junichi Soh, Katsuyuki Kiura, Hiroyuki Yanai
Publikováno v:
Anticancer Research. 40:4419-4423
Background/aim The histological features of lymph nodes (LNs) treated by chemoradiotherapy (CRT) in non-small cell lung cancer (NSCLC) have not been well studied. The purpose of this study was to evaluate the histological findings of LNs affected by