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Publikováno v:
Journal of Clinical Oncology. 41:1331-1338
PURPOSE Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the traditional ligand-binding assay (LBA). The purpose
Autor:
Mingxiao Li, Weiwei Zhang, Xuzhe Zhao, Chuanwei Yang, Hongyan Chen, Ming Li, Lin Song, Kefu Yu, Xiaohui Ren, Gehong Dong, Haihui Jiang, Yong Cui, Qinghui Zhu
Publikováno v:
Cancer Science
Pyrosequencing (PSQ) represents the golden standard for MGMT promoter status determination. Binary interpretation of results based on the threshold from the average of several CpGs tested would neglect the existence of the “gray zone”. How to def
Autor:
Kai Bachmann, Tarik Ghadban, Ronald Simon, Nathaniel Melling, Claudia Hube-Magg, Eugen Bellon, Michael Tachezy, Katharina Grupp, Jakob R. Izbicki, Guido Sauter
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Introduction Lysophosphatidylcholine acyltransferase 1 (LPCAT1) has repeatedly been suggested to be associated with tumorigenesis. To evaluate the role of LPCAT1 in esophageal cancer, LPCAT1 immunostaining was analyzed on a tissue microarray containi
Autor:
Michael J. Overman, Ryan W. Huey, Aurelio Matamoros, Kanwal Pratap Singh Raghav, Jeannelyn S. Estrella, Lianchun Xiao, Gauri R. Varadhachary, Shalini Makawita
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Cancer
BMC Cancer
Background Sarcomatoid carcinoma of unknown primary (SCUP) is a rare entity of either poorly differentiated carcinoma with sarcoma-like differentiation or a true mixed lineage neoplasm. Limited data regarding clinicopathological profile and managemen
Autor:
Seiji Yamada, Kiyonori Kuwahara, Shigeo Ohba, Masato Abe, Mitsuhiro Hasegawa, Eriel Sandika Pareira, Hikaru Sasaki, Shunsuke Nakae, Natsuki Hattori, Yuichi Hirose
Publikováno v:
Brain Tumor Pathology. 36:135-143
The genetic features of isocitrate dehydrogenase-wild-type (IDH-wt) lower-grade gliomas (LGGs; World Health Organization grades II and III) are not well defined. This study analyzed the genetic and other features of IDH-wt LGGs to develop a subclassi
Autor:
Lijie Song, Weili Tao, Xuxu Yu, Shunli Yu, Feng Wang, Minjie Yang, Shuang Tao, Yujin Lian, Yihui Ma, Xuejia Zhai, Qingxia Fan
Publikováno v:
Cancer Medicine, Vol 8, Iss 8, Pp 3729-3737 (2019)
Cancer Medicine
Cancer Medicine
Background Neuroendocrine tumors (NETs) are rare, which has resulted in a lack of published data on their epidemiology and clinical features. We therefore aimed to investigate the epidemiology, clinical features, treatments, and prognosis of patients
Autor:
Ronit Gurion, Uri Rozovski, Uri Abadi, Pia Raanani, Lee Peled, Martin Ellis, Pnina Rotman-Pikielny
Publikováno v:
Leukemia & Lymphoma. 60:2922-2926
The reported prevalence of hypercalcemia at diagnosis in non-Hodgkin-lymphoma ranges between 1.3% and 7.4%. These studies included all patients, regardless of lymphoma subtype. We performed a retrospective case-control study to determine the prevalen
Autor:
Yingyong Hou, Xiaodong Gao, Yong Fang, Qi Song, He Li, Anwei Xue, Wei Yuan, Yifang Xu, Ping Shu, Kuntang Shen, Chen Xu
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Gastrointestinal stromal tumors (GISTs) are typically solid neoplasms with small cystic change detected occasionally but in rare instances may present predominantly as cystic lesions. The histopathologic features and prognoses of cystic GISTs
Autor:
Genichiro Ishii, Hitoshi Masuda, Nobuaki Matsubara, Motohiro Kojima, Takashi Kuroe, Masato Sugano, Takeshi Kuwata, Ryo Morisue, Tetsuo Ushiku, Reiko Watanabe, Shioto Oda, Shota Kusuhara
Publikováno v:
Journal of cancer research and clinical oncology. 147(4)
Tumor necrosis (TN) is one of the unfavorable prognostic factors in renal cell carcinoma (RCC). We identified two patterns of TN according to their morphology: dirty necrosis and ghost necrosis. We aimed to elucidate the morphological features and un
Autor:
Pieter E. Postmus, Marloes A Smit, Wilma E. Mesker, Danielle Cohen, Mark Wh Philipsen, Rob A. E. M. Tollenaar, Hein Putter
Publikováno v:
Cancer Treatment and Research Communications, Vol 25, Iss, Pp 100247-(2020)
Objectives The tumor-stroma ratio (TSR) is based on the relative amount of stroma in the primary tumor and has proven to be an independent prognostic factor in various solid tumors. The prognosis of patients and adjuvant treatment decision making in