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Autor:
Darko Antic, Natasa Milic, Thomas Chatzikonstantinou, Lydia Scarfò, Vladimir Otasevic, Nina Rajovic, David Allsup, Alejandro Alonso Cabrero, Martin Andres, Monica Baile Gonzales, Antonella Capasso, Rosa Collado, Raul Cordoba, Carolina Cuéllar-García, Juan Gonzalo Correa, Lorenzo De Paoli, Maria Rosaria De Paolis, Giovanni Del Poeta, Maria Dimou, Michael Doubek, Maria Efstathopoulou, Shaimaa El-Ashwah, Alicia Enrico, Blanca Espinet, Lucia Farina, Angela Ferrari, Myriam Foglietta, Alberto Lopez-Garcia, José A. García-Marco, Rocío García-Serra, Massimo Gentile, Eva Gimeno, Maria Gomes da Silva, Odit Gutwein, Yervand K. Hakobyan, Yair Herishanu, José Ángel Hernández-Rivas, Tobias Herold, Gilad Itchaki, Ozren Jaksic, Ann Janssens, Olga B. Kalashnikova, Elżbieta Kalicińska, Arnon P. Kater, Sabina Kersting, Maya Koren-Michowitz, Jorge Labrador, Deepesh Lad, Luca Laurenti, Alberto Fresa, Mark-David Levin, Carlota Mayor Bastida, Lara Malerba, Roberto Marasca, Monia Marchetti, Juan Marquet, Biljana Mihaljevic, Ivana Milosevic, Fatima Mirás, Marta Morawska, Marina Motta, Talha Munir, Roberta Murru, Raquel Nunes, Jacopo Olivieri, Miguel Arturo Pavlovsky, Inga Piskunova, Viola Maria Popov, Francesca Maria Quaglia, Giulia Quaresmini, Gianluigi Reda, Gian Matteo Rigolin, Amit Shrestha, Martin Šimkovič, Svetlana Smirnova, Martin Špaček, Paolo Sportoletti, Oana Stanca, Niki Stavroyianni, Doreen Te Raa, Kristina Tomic, Sanne Tonino, Livio Trentin, Ellen Van Der Spek, Michel van Gelder, Marzia Varettoni, Andrea Visentin, Candida Vitale, Vojin Vukovic, Ewa Wasik-Szczepanek, Tomasz Wróbel, Lucrecia Yáñez San Segundo, Mohamed Yassin, Marta Coscia, Alessandro Rambaldi, Emili Montserrat, Robin Foà, Antonio Cuneo, Marc Carrier, Paolo Ghia, Kostas Stamatopoulos
Publikováno v:
Scientia
Journal of Hematology & Oncology, 15(1):116. BioMed Central
JOURNAL OF HEMATOLOGY & ONCOLOGY, 15(1):116. BioMed Central
Antic, Darko; Milic, Natasa; Chatzikonstantinou, Thomas; Scarfò, Lydia; Otasevic, Vladimir; Rajovic, Nina; Allsup, David; Alonso Cabrero, Alejandro; Andres, Martin; Baile Gonzales, Monica; Capasso, Antonella; Collado, Rosa; Cordoba, Raul; Cuéllar-García, Carolina; Correa, Juan Gonzalo; De Paoli, Lorenzo; De Paolis, Maria Rosaria; Del Poeta, Giovanni; Dimou, Maria; Doubek, Michael; ... (2022). Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL. Journal of hematology & oncology, 15(1), p. 116. BioMed Central 10.1186/s13045-022-01333-0
J Hematol Oncol . 2022 Aug 26;15(1):116
Journal of Hematology & Oncology, 15(1):116. BioMed Central
JOURNAL OF HEMATOLOGY & ONCOLOGY, 15(1):116. BioMed Central
Antic, Darko; Milic, Natasa; Chatzikonstantinou, Thomas; Scarfò, Lydia; Otasevic, Vladimir; Rajovic, Nina; Allsup, David; Alonso Cabrero, Alejandro; Andres, Martin; Baile Gonzales, Monica; Capasso, Antonella; Collado, Rosa; Cordoba, Raul; Cuéllar-García, Carolina; Correa, Juan Gonzalo; De Paoli, Lorenzo; De Paolis, Maria Rosaria; Del Poeta, Giovanni; Dimou, Maria; Doubek, Michael; ... (2022). Thrombotic and bleeding complications in patients with chronic lymphocytic leukemia and severe COVID-19: a study of ERIC, the European Research Initiative on CLL. Journal of hematology & oncology, 15(1), p. 116. BioMed Central 10.1186/s13045-022-01333-0
J Hematol Oncol . 2022 Aug 26;15(1):116
Background Patients with chronic lymphocytic leukemia (CLL) may be more susceptible to COVID-19 related poor outcomes, including thrombosis and death, due to the advanced age, the presence of comorbidities, and the disease and treatment-related immun
Autor:
Stefanie Kreutmair, Dietmar Pfeifer, Miguel Waterhouse, Ferenc Takács, Linda Graessel, Konstanze Döhner, Justus Duyster, Anna Lena Illert, Anna-Verena Frey, Michael Schmitt, Michael Lübbert
Publikováno v:
Cancer Immunology, Immunotherapy. 71:2913-2928
Wilms’ tumor 1 (WT1) protein is highly immunogenic and overexpressed in acute myeloid leukemia (AML), consequently ranked as a promising target for novel immunotherapeutic strategies. Here we report our experience of a phase I/II clinical trial (NC
Autor:
Ashish Panigrahi, Constantine S. Tam, Piers Blombery, Xiangting Chen, John F. Seymour, Dennis A. Carney, Andrew H. Wei, Thomas E Lew, Mary Ann Anderson, Andrew W. Roberts, Ella R. Thompson, David C. S. Huang, Tamia Nguyen, David Westerman, Michael A. Dengler, Victor S Lin, Sasanka M. Handunnetti, Jerry M. Adams
Publikováno v:
Blood. 139:1198-1207
The BCL2 inhibitor venetoclax has established therapeutic roles in chronic lymphocytic leukemia (CLL) and acute myeloid leukemia (AML). As BCL2 is an important determinant of survival of both myeloid progenitor and B cells, we investigated whether cl
Autor:
Liang Zhao, L. Green, T. Dougan, Haesook T. Kim, Christopher D. Gocke, J. Tsuji, Madeleine Duran, Siqing Wang, Amy E. DeZern, Brendan Blumenstiel, Sarah Nikiforow, Richard J. Jones, Niall J. Lennon, Yi-Bin Chen, Mark Fleharty, Christopher J. Gibson, Lukasz P. Gondek, Alana F. Ogata, David R. Walt, Vincent T. Ho, Chi-An Cheng, R. C. Lindsley, Jerome Ritz, Rafael Madero-Marroquin, H. M. Murdock, Joseph H. Antin, Bryan C. Hambley, Robert J. Soiffer, Carrie Cibulskis
Publikováno v:
Journal of Clinical Oncology. 40:189-201
PURPOSEClonal hematopoiesis (CH) can be transmitted from a donor to a recipient during allogeneic hematopoietic cell transplantation. Exclusion of candidate donors with CH is controversial since its impact on recipient outcomes and graft alloimmune f
Autor:
Ying Yu, Bing Liu, Xuexiang Li, Dingheng Lu, Likun Yang, Liang Chen, Yunxue Li, Lulin Cheng, Fang Lv, Pu Zhang, Yarong Song, Yifei Xing
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-13 (2022)
Cell Death & Disease
Cell Death & Disease
The survival of cancer cells after detaching from the extracellular matrix (ECM) is essential for the metastatic cascade. The programmed cell death after detachment is known as anoikis, acting as a metastasis barrier. However, the most aggressive can
Autor:
Xun Fu, Jianmin Liu, Daoquan Liu, Yongying Zhou, Yuhang Guo, Zhen Wang, Shu Yang, Weixiang He, Ping Chen, Xinghuan Wang, Michael E. DiSanto, Xinhua Zhang
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-13 (2022)
Cell Death & Disease
Cell Death & Disease
Benign prostatic hyperplasia (BPH) is a chronic condition which mainly affects elderly males. Existing scientific evidences have not completely revealed the pathogenesis of BPH. Glucose-regulated protein 78 (GRP78) is a member of the heat shock prote
Autor:
Ryusaku Matsumoto, Masaaki Yamamoto, Genzo Iguchi, Shin Urai, Hidenori Fukuoka, Wataru Ogawa, Kentaro Suda, Hiroki Shichi, Keitaro Kanie, Yutaka Takahashi, Hironori Bando, Yasunori Fujita
Publikováno v:
Cancer Immunology, Immunotherapy
Background Immune checkpoint inhibitors (ICIs) as a cancer immunotherapy have emerged as a treatment for multiple advanced cancer types. Because of enhanced immune responses, immune-related adverse events (irAEs), including endocrinopathies such as h
Autor:
Jinping Gao, Gang Chen, Yujun Sheng, Xing Fan, Ze Guo, Liangdan Sun, He Huang, Xianfa Tang, Hui Cheng, Huayang Tang, Xiaodong Zheng, Wenjun Wang
Publikováno v:
Immunology Letters. 240:98-105
Psoriasis is an immune-mediated genetic disease involving innate and the adaptive immune system. Aurora kinase A (AURKA) belongs to a seine/threonine kinases family and is elevated in lesional psoriatic tissues. This research aimed to investigate the
Autor:
Eva Karamitopoulou, Aurélie Pahud de Mortanges, Aurel Perren, Beat Gloor, Andreas Andreou, Marianne Tinguely
Publikováno v:
Cancer Immunology Research. 9:1439-1450
Immunotherapy, including PD-1/PD-L1 agonists, has shown limited efficacy in pancreatic ductal adenocarcinoma (PDAC). We examined the PD-1/PD-L1 expression and immunoarchitectural features by automated morphometric analysis using multiplex immunofluor
Publikováno v:
Human Immunology. 82:950-959
Background Right-sided colorectal cancer (RCRC) and left-sided colorectal cancer (LCRC) harbor different genetic alterations associated with immune response. Objective This study aimed to analyze the differences in T cell immune-related RNA expressio