Zobrazeno 1 - 10
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pro vyhledávání: ''
Autor:
Ning Li, Huizhen Geng, Jianfei Shi, Bin Li, Jinfeng Wang, Fei Yin, Cuizhen Li, Xiaolei Yin, Zibo Li, Man Zhao, Bing Peng
Publikováno v:
BioFactors. 47:1042-1052
The effectively early detection and determination of disease progression of gastric cancer (GC) are still required. An emerging demand for identifying the novel targets adherent to cancer cells has been still challenged since those valuable profiling
Autor:
Yanshuo Cao, Lin Shen, Jiajia Yuan, Jifang Gong, Chenyu Mao, Da Jiang, Jianmin Fang, Yuxian Bai, Zhenghang Wang, Xinan Sheng, Qingxia Fan, Changsong Qi, Yi Ba, Dan Liu, Fen Yang, Yakun Wang, Yingying Xu, Zhi Peng, Ming Lu, Xiaotian Zhang, Jian Li, Xicheng Wang, Jun Zhou
Publikováno v:
Gastric Cancer
Purpose RC48 contains the novel humanized anti-HER2 antibody hertuzumab conjugated to MMAE via a cleavable linker. A phase I study was initiated to evaluate the toxicity, MTD, PK, and antitumor activity of RC48 in patients with HER2-overexpressing lo
Tertiary lymphoid structures show infiltration of effective tumor‐resident T cells in gastric cancer
Autor:
Yoshihito Yamakoshi, Yuichiro Miki, Mami Yoshii, Sota Deguchi, Shugo Suzuki, Takuya Mori, Tatsuro Tamura, Kazuya Muguruma, Takahiro Toyokawa, Shigeru Lee, Masaichi Ohira, Hideki Wanibuchi, Hiroaki Tanaka
Publikováno v:
Cancer Science
Several studies have reported that tissue‐resident memory T cells (TRM cells) or tertiary lymphoid structures (TLSs) are associated with a good prognosis. The aim of this study was to clarify the association of TRM cells and TLSs in the tumor immun
Autor:
Mitsuaki Hirose, Masashi Sato, Ichinosuke Hyodo, Mamiko Imanishi, Kenji Yamato, Akinori Sugaya, Xiaoxuan Wang, Toshikazu Moriwaki, Xiaochen Zhang, Shinji Endo, Yoshiyuki Yamamoto
Publikováno v:
Anticancer Research. 41:1475-1483
Background/aim The oncoproteins murine double minute (MDM) 2 and MDM4 inactivate tumor-suppressor protein p53. Their mutual relationship with the prognosis of gastric cancer (GC) remains unknown. Patients and methods Expression of MDM2, MDM4, and p53
Autor:
Junyi Ye, Shanai Song, Haiwei Du, Zhou Zhang, Haiyan Li, Ning Liu, Zimin Liu, Xiaoxiao Li, Lu Zhang, Mingpeng Shi
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose The identification of HER2 overexpression in a subset of gastric adenocarcinoma (GA) patients represents a significant step forward in unveiling the molecular complexity of this disease. The predictive and prognostic value of HER2 amplificati
Autor:
Tomio Arai, Hideyuki Ishida, Erito Mochiki, Minoru Fukuchi, Tatsuro Yamaguchi, Kiwamu Akagi, Okihide Suzuki
Publikováno v:
Anticancer Research. 41:975-982
Background/aim DNA mismatch repair (MMR) deficiency has received increasing attention as a biomarker of anti-PD-1 treatments of solid tumors including gastric cancer (GC). However, efficient screening has not been established. Patients and methods A
Autor:
Michihiro Kudou, Shuhei Komatsu, Tomohiro Arita, Keita Katsurahara, Hirotaka Konishi, Hiroki Shimizu, Atsushi Shiozaki, Eigo Otsuji, Takeshi Kubota, Kazuma Okamoto, Toshiyuki Kosuga, Eiichi Konishi, Mitsuo Kishimoto, Hitoshi Fujiwara
Publikováno v:
Cancer Science
The function of ANO9 in gastrointestinal cancer remains unclear. We investigated the biological behaviors and clinical prognostic values of ANO9 in gastric cancer (GC). Knockdown experiments were performed on human GC cell lines using ANO9 siRNA. Eig
Autor:
Jing Dai, Shangshang Hu, Yu Gao, Jinyan Zhang, Mulin Liu, Shuanhu Wang, Zhaogen Cai, Yunxia Zhao
Publikováno v:
Bioengineered, Vol 12, Iss 1, Pp 5641-5654 (2021)
Bioengineered
article-version (VoR) Version of Record
Bioengineered
article-version (VoR) Version of Record
To investigate the potential role of GXYLT2 (glucoside xylosyltransferase 2) in gastric cancer (GC), the TCGA (The Cancer Genome Atlas) database and Gene Expression Omnibus (GEO) dataset were used to evaluate GXYLT2 mRNA expression, and the standardi
Autor:
Riccardo Bernasconi, Giorgio Ercolani, Laura Capelli, Paola Ulivi, Chiara Molinari, Maria Raffaella Ambrosio, Giovanni Martinelli, Alessia D'Ignazio, Luca Saragoni, Paolo Morgagni, Leonardo Solaini, Anna Tomezzoli, Gianluca Tedaldi, Emanuela Scarpi, Sara Ravaioli, Francesca Rebuzzi, Maria Maddalena Tumedei, Francesco Limarzi
Publikováno v:
Gastric Cancer. 24:392-401
Background: Early Gastric Cancer (EGC) reaches 25% of the gastric cancers surgically treated in some areas of Northeastern Italy and is usually characterized by a good prognosis. However, among EGCs classified according to Kodama’s criteria, Pen A
Autor:
Atsushi Sugimoto, Masaichi Ohira, Shingo Togano, Yuichiro Miki, Kenji Kuroda, Tomohisa Okuno, Shuhei Kushiyama, Sadaaki Nishimura, Masakazu Yashiro, Yurie Yamamoto, Tomohiro Sera
Publikováno v:
Cancer Science
Fibroblast growth factor receptor (FGFR) is associated with proliferation, migration, and angiogenesis of carcinomas, and FGFR signaling inhibitors are considered a key drug for the treatment of solid tumors with FGFR overexpression. Amplification of