Zobrazeno 1 - 10
of 11 522
pro vyhledávání: ''
Autor:
Jinjing Zhong, Miao Xu, Zhengzheng Su, Mengni Zhang, Tianping Yu, Ling Nie, Jing Gong, Xueqin Chen, Ni Chen, Qiao Zhou
Publikováno v:
Cancer Letters. 530:68-84
Glioma-associated oncogene homolog 1 (GLI1) is a core component of the Hedgehog (HH) signalling pathway and is a transcription activator of numerous oncogenes, such as SOX9, VEGFA, BCL2, and CDK2. The complex regulation of GLI1 involves numerous path
Autor:
Paul Mitchell, G Rivalland, Hui Yu, Fred R. Hirsch, R. Mosher, L Churilov, K Asadi, Christopher J. Rivard, S Heynemann
Publikováno v:
Clinical Lung Cancer. 23:e90-e98
Background NaPi2b is a multi-transmembrane sodium-dependent phosphate transporter expressed at normal levels in several organs, including lung. High expression levels have been reported in various tumours including breast, thyroid, ovarian and non-sm
Publikováno v:
Anticancer Research. 42:1301-1306
Background/aim: Functional and bioinformatic studies provide strong evidence that long non-coding RNAs (lncRNAs) can alter the molecular mechanisms of cancer through their interactions with DNA, RNAs, and proteins. This study aimed to evaluate the ro
Autor:
Xianxian Wu, Hongdian Zhang, Zhilin Sui, Yongyin Gao, Lei Gong, Chuangui Chen, Zhao Ma, Peng Tang, Zhentao Yu
Publikováno v:
Cancer Science. 113:926-939
C-X-C motif chemokine receptor 4 (CXCR4) belongs to the CXC chemokine receptor family, which mediates the metastasis of tumor cells and promotes the malignant development of cancers. However, its biological role and regulatory mechanism in esophageal
Autor:
Yu-Zhong Yu, Dao-Jun Lv, Chong Wang, Xian-Lu Song, Tao Xie, Tao Wang, Zhi-Min Li, Jia-Ding Guo, Du-Jiang Fu, Kang-Jin Li, Ding-Lan Wu, Franky Leung Chan, Ning-Han Feng, Zhe-Sheng Chen, Shan-Chao Zhao
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-21 (2022)
Molecular Cancer
Molecular Cancer
Background More and more studies have shown that circular RNAs (circRNAs) play a critical regulatory role in many cancers. However, the potential molecular mechanism of circRNAs in prostate cancer (PCa) remains largely unknown. Methods Differentially
Autor:
Ying Yu, Bing Liu, Xuexiang Li, Dingheng Lu, Likun Yang, Liang Chen, Yunxue Li, Lulin Cheng, Fang Lv, Pu Zhang, Yarong Song, Yifei Xing
Publikováno v:
Cell Death and Disease, Vol 13, Iss 1, Pp 1-13 (2022)
Cell Death & Disease
Cell Death & Disease
The survival of cancer cells after detaching from the extracellular matrix (ECM) is essential for the metastatic cascade. The programmed cell death after detachment is known as anoikis, acting as a metastasis barrier. However, the most aggressive can
Publikováno v:
Cancer Medicine, Vol 11, Iss 2, Pp 492-506 (2022)
Cancer Medicine
Cancer Medicine
Background and Aims Cancer‐associated stroma (CAS) is emerging as a key determinant of metastasis in colorectal cancer (CRC); however, little is known about CAS in colorectal liver metastases (CRLM). This study aimed to validate the prognostic sign
Autor:
Shinji, Mizuochi, Jun, Akiba, Reiichiro, Kondo, Hironori, Kusano, Taro, Shioga, Keiichi, Kondo, Kana, Tsutsui, Masamichi, Nakayama, Sachiko, Ogasawara, Yoshiki, Naito, Osamu, Nakashima, Hirohisa, Yano
Publikováno v:
Anticancer Research. 42:449-457
Non-B non-C hepatocellular carcinomas (NBNC-HCCs) are larger than hepatitis virus-related HCCs. We conducted a clinicopathological study of patients who underwent curative NBNC-HCC resection, including proliferative activity assessments, such as nucl
Autor:
IMAN M. TALAAT, EMAN ABU-GHARBIEH, AMAL HUSSEIN, MAHMOOD HACHIM, ISRAA SOBHY, MOHAMED ELADL, WASEEM EL-HUNEIDI
Publikováno v:
Anticancer Research. 42:355-362
Renal cell carcinoma (RCC) is among the most common renal malignancies and requires reliable biomarkers for optimum diagnosis and prognosis. Copines are a family of calcium-dependent phospholipid-binding proteins that were reported to be associated w
Autor:
Yukyung Jun, Yun-Suhk Suh, SungHee Park, Jieun Lee, Jong-Il Kim, Sanghyuk Lee, Wan-Ping Lee, Olga Anczuków, Han-Kwang Yang, Charles Lee
Publikováno v:
Cancer Research. 82:543-555
Alternatively spliced RNA isoforms are a hallmark of tumors, but their nature, prevalence, and clinical implications in gastric cancer have not been comprehensively characterized. We systematically profiled the splicing landscape of 83 gastric tumors