Zobrazeno 1 - 10
of 1 739
pro vyhledávání: ''
Autor:
Shaohua Ma, Juan Chen, Peng Ren, Liang Jing, Yan Li, Yunfan Ma, Jieda Cui, Xuexia Tong, Chutong Lin, Jingdi Wang
Publikováno v:
Thoracic Cancer
Thoracic Cancer, Vol 12, Iss 18, Pp 2449-2457 (2021)
Thoracic Cancer, Vol 12, Iss 18, Pp 2449-2457 (2021)
Objective Non‐small‐cell lung cancer (NSCLC) is one of the most common fatal cancers in the world. Although the treatment of NSCLC has been significantly improved, there is still an unmet need to identify novel targets for developing therapeutic
Publikováno v:
International Journal of Medical Sciences
Objective: To study the expression and clinical value of PD-L1 gene in pancreatic cancer, and to predict the role of PD-L1 gene in the development of pancreatic cancer. Methods: The pancreatic cancer datasets were downloaded from the Cancer Genome At
Autor:
Maria A. Trujillo, Zainab I. Alruwaii, Ralph H. Hruban, Michael C. Haffner, Michael Goggins, Nicholas J. Roberts, Sujayita Roy, Alan K. Meeker, Jin He, Michael J. Wright, Kohei Fujikura, Ding Ding, Seung-Mo Hong, Anne Macgregor-Das, Laura D. Wood
Publikováno v:
J Pathol
Epigenetic alterations are increasingly recognized as important contributors to the development and progression of pancreatic ductal adenocarcinoma. 5-hydroxymethylcytosine (5hmC) is an epigenetic DNA mark generated through the ten-eleven translocati
Autor:
Kazuma Okamoto, Tomohiro Arita, Takeshi Kubota, Shuhei Komatsu, Daiki Matsubara, Katsutoshi Shoda, Eigo Otsuji, Atsushi Shiozaki, Hiroki Shimizu, Koji Takao, Yusuke Yamamoto, Hitoshi Fujiwara, Hirotaka Konishi
Publikováno v:
Anticancer Research. 41:2441-2449
BACKGROUND/AIM The regulation of gene expression by miRNAs plays an important role in cancer progression. Here, we investigated the role of miR-3663-3p in gastric cancer. PATIENTS AND METHODS The relationship between miR-3663-3p expression, clinicopa
Autor:
Beiying Dai, Hongbao Yang, Jifeng Feng, Yaohong Shi, Decai Yu, Lanxin Li, Jiaping Ni, Duowei Wang, Guilai Liu, Amir Hossain, Mo Wu, Weiwei Hu, Lutz Birnbaumer, Yong Yang, Hanrui Bian, Yumeng Shen, Shufang Zheng, Haixin Guo, Zhoutong Tian, Qin Zhang, Jun Yu
Publikováno v:
Hepatology. 73:674-691
Background and aims Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide, hence a major public health threat. Pleomorphic adenoma gene like-2 (PLAGL2) has been reported to play a role in tumorigenesis. However,
Publikováno v:
Cancer Research. 81:344-355
Circular RNAs (circRNA) are a new member of endogenously produced noncoding RNAs that have been characterized as key regulators of gene expression in a variety of malignances. However, the role of circRNA in oral squamous cell carcinoma (OSCC) remain
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Gastric cancer (GC) is a leading cause of cancer-induced mortality, with poor prognosis with metastasis. The mechanism of gastric carcinoma lymph node metastasis remains unknown due to traditional bulk-leveled approaches masking the roles of subpopul
Autor:
Muwen Wang, Zilian Cui, Peng Sun, Qiang Wang, Hanbo Wang, Yun Dai, Dong Zhang, Jin Wang, Weiting Kang, Taiguo Qi, Xunbo Jin
Publikováno v:
Cell Death and Disease, Vol 11, Iss 12, Pp 1-16 (2020)
Cell Death & Disease
Cell Death & Disease
Apart from being potential prognostic biomarkers and therapeutic targets, long non-coding RNAs (lncRNAs) modulate the development and progression of multiple cancers. PlncRNA-1 is a newly discovered lncRNA that exhibits the above properties through m
Autor:
Fang Hua, Bing Cui, Yu-fen Yuan, Yang Xiao, Zaiwuli Yeerjiang, Chen-xi Zhao, Xiaowei Zhang, Ting-ting Zhang, Xiaoxi Lv, Jiao-jiao Yu, Zhao-na Yang, Shan-Shan Liu, Feng Wang, Zhuo-Wei Hu, Ke Li, Shuang Shang, Jin-mei Yu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Nature Communications
Nature Communications
The transcription factor MYC is deregulated in almost all human cancers, especially in aggressive lymphomas, through chromosomal translocation, amplification, and transcription hyperactivation. Here, we report that high expression of tribbles homolog
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2020 (2020)
BioMed Research International, Vol 2020 (2020)
Objective. DLGAP1-AS2 has been characterized as an oncogenic lncRNA in glioma. Our preliminary microarray analysis revealed the altered expression of DLGAP1-AS2 in hepatocellular carcinoma (HCC), but the role of DLGAP1-AS2 in HCC remains unknown. Met