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Autor:
Paul Mitchell, G Rivalland, Hui Yu, Fred R. Hirsch, R. Mosher, L Churilov, K Asadi, Christopher J. Rivard, S Heynemann
Publikováno v:
Clinical Lung Cancer. 23:e90-e98
Background NaPi2b is a multi-transmembrane sodium-dependent phosphate transporter expressed at normal levels in several organs, including lung. High expression levels have been reported in various tumours including breast, thyroid, ovarian and non-sm
Publikováno v:
Thoracic Cancer, Vol 12, Iss 24, Pp 3356-3369 (2021)
Thoracic Cancer
Thoracic Cancer
Background Lung cancer is the most prevalent malignancy in adults. Circular RNA (circRNA) circCPA4 (hsa_circ_0082374) is highly expressed in non‐small cell lung cancer (NSCLC). The purpose of this study was to explore the role and mechanism of circ
Autor:
Chen-xing Zhao, Jianda Hu, Li Wang, Di Fu, Pengpeng Xu, Jing-jing Wen, Zi-Xun Yan, Shu Cheng, Wei-Li Zhao
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-17 (2021)
Molecular Cancer
Molecular Cancer
Background Epstein-Barr virus (EBV) represents an important pathogenic factor of lymphoma and is significantly associated with poor clinical outcome of diffuse large B-cell lymphoma (DLBCL). Circular RNAs (circRNAs) play an essential role in lymphoma
Autor:
Serdar Kalemci, Tuba Gökdoğan Edgünlü, Mehmet Emin Erdal, Mehmet Tuğhan Kızıltuğ, Arife Zeybek, Necdet Öz, Kursad Tosun, Leyla Tekin
Publikováno v:
Molecular Biology Reports. 49:9-17
We aimed to examine the expression levels of the genes encoding adenomatous polyposis coli (APC) 1, APC-2, Dickkopf related protein (DKK)-1, DKK-3, secreted frizzled-related protein (SFRP)-2, SFRP-4, and SFRP-5, which play roles in the Wnt signaling
Autor:
Wen-Jie Luo, Dingwei Ye, Yongqiang Huang, Yuan-Yuan Qu, Wenhao Xu, Mengfei Yao, Jun Wang, Chunguang Ma, Yiping Zhu, Hailiang Zhang, Fangning Wan
Publikováno v:
Cell Death and Disease, Vol 12, Iss 11, Pp 1-11 (2021)
Cell Death & Disease
Cell Death & Disease
Long non-coding RNAs (lncRNAs) act as important regulators of tumorigenesis and development in bladder cancer. However, the underlying molecular mechanisms remain elusive. We previously identified a novel lncRNA signature related to immunity and prog
Autor:
Mireia Martín-Satué, Marçal Pastor-Anglada, Loreto Boix, Clara Boces-Pascual, Aida Mata-Ventosa, Meritxell Gironella, Sandra Pérez-Torras
Publikováno v:
Cellular and Molecular Life Sciences
Dipòsit Digital de la UB
Universidad de Barcelona
Dipòsit Digital de la UB
Universidad de Barcelona
Graphic abstract High-affinity uptake of natural nucleosides as well as nucleoside derivatives used in anticancer therapies is mediated by human concentrative nucleoside transporters (hCNTs). hCNT1, the hCNT family member that specifically transports
Autor:
André Salim Khayat, Ana Paula Silva de Azevedo dos Santos, Edivaldo Herculano Corrêa de Oliveira, Jenilson da Silva, Luciane R. Cavalli, Leudivan Ribeiro Nogueira, Amanda Jordão Silva de Deus, Rafael Marchi, Silma Regina Ferreira Pereira, Ronald Coelho
Publikováno v:
Cancer Biomarkers. 32:147-160
BACKGROUND: Penile cancer (PeCa) is a rare disease, but its incidence has increased worldwide, mostly in HPV+ patients. Nevertheless, there is still no targeted treatment for this carcinoma. OBJECTIVE: To predict the main signaling pathways involved
Autor:
Yunze Liu, Shuai Gong, Xiuzhong Zhang, Penbo Zhang, Nai Wu, Fanchao Meng, Chong Zhang, Zeqiang Ren, Yi Zhang, Zhao Liu, Xin Liu, Jun Song, Changwei Lin, Lei Xu
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-19 (2021)
Molecular Cancer
Molecular Cancer
Background Circular RNAs (circRNAs) play important roles in cancer progression and metabolism regulation. Serine/glycine metabolism supports the growth of cancer cells by contributing to their anabolic demands and epigenome as well as by regulating t
Autor:
Masanori Kitamura, Hitoshi Hanamoto, Ayana Suzuki, Shin-ichi Nakatsuka, Jun Ishikawa, Shigeo Fuji, Yoji Kukita, Yuichiro Hamamoto, Tomoko Wakasa, Eiichi Morii, Keiichiro Honma, Mitsuyoshi Hirokawa, Masako Kurashige, Hiroaki Masaie
Publikováno v:
Histopathology. 79:521-532
Aims Follicular lymphoma (FL), comprising a minor subset of primary thyroid lymphomas, is divided into two groups based on Bcl-2 expression and IGH-BCL2 translocation. The clinicopathological features exhibited by Bcl-2-negative IGH-BCL2 translocatio
Autor:
Saisai Wang, Dong Chen, Zhou Tong, Yongfeng Ding, Lulu Liu, Ruyi Zhang, Min Zhang, Xuanwen Bao, Weijia Fang, Peng Zhao, Hangyu Zhang, Xiaolin Li, Xiaohu Zhou, Yi Zheng, Benfeng Li, Jian Ruan, Xiaofei Cheng
Publikováno v:
Br J Cancer
BACKGROUND: Colorectal neuroendocrine carcinomas (CRNECs) are highly aggressive tumours with poor prognosis and low incidence. To date, the genomic landscape and molecular pathway alterations have not been elucidated. METHODS: Tissue sections and cli