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Publikováno v:
Breast Disease. 40:S63-S70
BACKGROUND: Phyllodes tumors (PTs) are rare fibroepithelial breast tumors with diverse biological behavior. OBJECTIVE: This study aimed to analyze the characteristics, management, and outcome of phyllodes tumors. METHODS: Patients diagnosed with PTs
Autor:
Shengmin Chen, Weifeng Wang, Huanliang Wu, Feng Yuan, Zhiren Lin, Gang Cheng, Shaohua Peng, Yunxiu Luo
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 147:2913-2922
Assessing the downstaging effects of neoadjuvant chemotherapy (NACT) in patients with locally advanced nasopharyngeal carcinoma (LANPC) and predicting response to treatment remain challenging. The present study aimed to evaluate the long-term prognos
Autor:
Xiangjuan Ma, Di Wu, Jieran Long, Guangming Tian, Jian Fang, Jindi Han, Yang Wang, Ziran Zhang, Jie Zhang, Jun Nie, Weiheng Hu, Sen Han, Ling Dai, Xiaoling Chen
Publikováno v:
Cancer Immunology, Immunotherapy
Background The combination of PD-1/PD-L1 inhibitor and chemotherapy has been clinically confirmed to be beneficial as the first-line treatment of patients with advanced NSCLC. This study aimed to assess the effect of nivolumab + docetaxel versus nivo
Autor:
Motohiro Fujiwara, Yoshinobu Komai, Shinya Yamamoto, Ryo Fujiwara, Tomohiko Oguchi, Noboru Numao, Shotaro Yasuoka, Junji Yonese, Takeshi Yuasa
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:525-531
In this study, we investigated the association between the early response of serum and hematological variables and the outcome of cabazitaxel therapy. The medical records of 59 consecutive patients who had previously received docetaxel chemotherapy f
Autor:
Suguru Fukuhara, Koji Izutsu, Wataru Munakata, Junko Nomoto, Akiko Miyagi-Maeshima, Shinichi Makita, Yuta Ito, Shunsuke Hatta, Dai Maruyama, Sayako Yuda, Hirokazu Taniguchi, Kinuko Tajima, Yukio Kobayashi, Kensei Tobinai, Tatsuya Suzuki, Tomotaka Suzuki
Publikováno v:
Cancer Medicine, Vol 10, Iss 15, Pp 5101-5109 (2021)
Cancer Medicine
Cancer Medicine
Background Approximately 15% of patients with diffuse large B‐cell lymphoma (DLBCL) experience refractory or early relapsed disease after initial rituximab‐containing chemoimmunotherapy is regarded as a primary refractory disease. Although the st
Autor:
Jose Mauricio Mota, Min Yuen Teo, Karissa Whiting, Samuel Funt, Chung-Han Lee, Han A Li, Gopa Iyer, Jonathan E. Rosenberg, Ashely M Regazzi, Dean F. Bajorin, Irina Ostrovnaya
Publikováno v:
J Immunother
Eosinophils influence antitumor immunity and may predict response to treatment with immune checkpoint inhibitors (ICIs). To examine the association between blood eosinophil counts and outcomes in patients with advanced or metastatic urothelial carcin
Publikováno v:
Future Oncology. 17:2183-2192
Aim: To investigate the benefit of chemotherapy among early-stage breast cancer patients with 21-gene recurrence scores of 26–30. Methods: We identified 3754 patients in the Surveillance, Epidemiology, and End Results database. Results: 57.6% of th
Autor:
Benjamin O. Anderson, Adewale O. Adisa, T. Peter Kingham, Ngozi R. Monu, Emmanuella Onabanjo, Adeleye D. Omisore, Mary L. Gemignani, Olusegun I. Alatise, Adeolu O. Arowolo, O C Famurewa, Oluwole O. Odujoko, Debra A. Goldman, Gregory C. Knapp, Olalekan Olasehinde, Jeremy Constable, Anya Romanoff
Publikováno v:
Oncologist
Background Neoadjuvant chemotherapy (NAC) is an integral component of T4 breast cancer (BCa) treatment. We compared response to NAC for T4 BCa in the U.S. and Nigeria to direct future interventions. Materials and Methods Cross-sectional retrospective
Autor:
Giampiero Porzio, Luigi Della Gravara, Carlo Genova, Danilo Rocco, Luca Cantini, Sebastiano Buti, Sergio Bracarda, Marco Filetti, Alessandro Tuzi, R. Bisonni, Giulio Metro, Claudia Bareggi, Francesco Grossi, Francesca Mazzoni, Alfredo Addeo, David J. Pinato, Emilio Bria, Giovanni Mansueto, Vincenzo Adamo, Joachim G.J.V. Aerts, Raffaele Giusti, Diego Signorelli, Alessio Cortellini, Miriam Grazia Ferrara, Giorgia Guaitoli, Lorenza Landi, Corrado Ficorella, Gabriele Minuti, Fabiana Perrone, Fabrizio Citarella, Melissa Bersanelli, Giuseppe Luigi Banna, Emanuela Olmetto, Marina Chiara Garassino, Marco Siringo, Alain Gelibter, Michele De Tursi, Marco Russano, Giulia Mazzaschi, Gian Paolo Spinelli, Vincenzo Sforza, Luca Carmisciano, Rita Chiari, Katia Cannita, Fabrizio Tabbò, Diego Cortinovis, Alessandro De Toma, Serena Ricciardi, Stefania Gori, Olga Nigro, Mariangela Torniai, Rossana Berardi, Marcello Tiseo, Maria Rita Migliorino, Fausto Barbieri, Alessandro Follador, Alessandro Russo, Massimo Di Maio, Pietro Di Marino, Alex Friedlaender, Federica Zoratto
Publikováno v:
European Journal of Cancer, 150, 224-231. Elsevier Ltd.
Background: We previously demonstrated the cumulative poor prognostic role of concomitant medications on the clinical outcome of patients with advanced cancer treated with immune checkpoint inhibitors, creating and validating a drug-based prognostic
Autor:
Sho Miyamoto, Shinichiro Kina, Hajime Sunakawa, Takao Kinjo, Reika Kawabata-Iwakawa, Akira Arasaki
Publikováno v:
Journal of Drug Targeting. 29:1118-1127
Well-differentiated head and neck squamous cell carcinoma (HNSCC), accounts for approximately 10% of all HNSCCs and, while these cases are associated with good prognosis after surgery, these are resistant to chemotherapy. Here we designed a retrospec