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Autor:
Abdilkerim Oyman, Aygül Koseoglu, Merve Turan, Serdar Arici, Mustafa Basak, Seval Ay, Deniz Tataroğlu Özyükseler, Hatice Odabas, Heves Sürmeli, Nedim Turan, Mahmut Emre Yıldırım
Publikováno v:
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners. 27(3)
Background Ado-trastuzumab emtansine is an antibody-drug conjugate that combines the cytotoxic activity of emtansine with human epidermal growth factor receptor 2-targeted antitumor features of trastuzumab. Objective We conducted a study of metastati
Autor:
Stefan Boeck, Volker Heinemann, Michael Haas, Julia Mayerle, Michael von Bergwelt-Baildon, Michael Guenther, Stephan Kruger, Christoph B. Westphalen, Jens Werner, Steffen Ormanns, Thomas Kirchner
Publikováno v:
British Journal of Cancer
Background Gram-negative bacteria mediated gemcitabine resistance in pre-clinical models. We determined if intratumoural lipopolysaccharide (LPS) detection by immunohistochemistry is associated with outcome in advanced pancreatic ductal adenocarcinom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dcec7b9872d2d88285a94283e97af3e
Autor:
Ilse van Engen-van Grunsven, Gerald W. Verhaegh, Stefan M. Willems, Wim van Boxtel, Maike J. M. Uijen, Jack A. Schalken, Marianne A. Jonker, Carla M.L. van Herpen
Publikováno v:
Oral Oncology, 110:105018. ELSEVIER SCIENCE BV
Oral Oncology, 110
Oral Oncology, 110
Objectives: Salivary duct carcinoma (SDC) is a rare and aggressive subtype of salivary gland cancer. Androgen receptor (AR) (96%) and HER2 (29-46%) expression, and a high propensity for regional lymph node metastases are hallmarks of the disease. We
Autor:
Tilman Kühn, Christina C. Dahm, Bas Bueno-de-Mesquita, Rosario Tumino, Aurora Perez-Cornago, Mazda Jenab, W. Dana Flanders, Antonia Trichopoulou, David C. Gibbs, Veronika Fedirko, Elisabete Weiderpass, Marjorie L. McCullough, Caroline Y. Um, Inger T. Gram, Björn Gylling, Sandra Colorado-Yohar, Alicia K Heath, Roberd M. Bostick
Publikováno v:
Gibbs, D C, Bostick, R M, McCullough, M, Um, C, Flanders, D, Jenab, M, Weiderpass, E, Gylling, B, Gram, I T, Heath, A K, Colorado-Yohar, S, Dahm, C C, Bueno-de-Mesquita, B, Perez-Cornago, A, Trichopoulou, A, Tumino, R, Kühn, T & Fedirko, V 2020, ' Association of pre-diagnostic vitamin D status with mortality among colorectal cancer patients differs by common, inherited vitamin D-binding protein isoforms ', International Journal of Cancer, vol. 147, no. 10 . https://doi.org/10.1002/ijc.33043
Int J Cancer
Int J Cancer
Lower prediagnostic circulating 25-hydroxyvitamin D (25[OH]D)—considered the best marker of total vitamin D exposure—is associated with higher mortality risk among colorectal cancer (CRC) patients. However, it is unknown whether this association
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a36a4a22a5aa755b1d1a1689b3ac7966
http://hdl.handle.net/10044/1/79602
http://hdl.handle.net/10044/1/79602
Autor:
Ralph V. Boccia, Kimberly Bogard, Stephen J. Noga, Robert M. Rifkin, Habte A. Yimer, Sudhir Manda, Haresh S. Jhangiani, Roger M. Lyons, Brittany Demers, Renda H. Ferrari, Suman Kambhampati, Dasha Cherepanov, Ruemu Ejedafeta Birhiray, Veena Charu, Christopher A. Yasenchak, Saulius Girnius, Jack Aiello, Presley Whidden, Vickie Lu
Publikováno v:
Clinical Lymphoma, Myeloma & Leukemia
Background The ongoing US MM-6 study is investigating in-class transition (iCT) from parenteral bortezomib-based induction to all-oral ixazomib-lenalidomide-dexamethasone (ixazomib-Rd) with the aim of increasing proteasome inhibitor (PI)-based treatm
Autor:
Daqin Suo, Lili Liang, Zhi Tang, Yunfei Yuan, Lei Li, Yan Li, Jiangchao Li, Xin Yuan Guan, Tingting Zeng
Publikováno v:
Molecular Oncology
Unlike full‐length PDSS2, which has a tumor‐suppressive function, PDSS2‐Del2 promoted HCC metastasis and angiogenesis. Positive staining for PDSS2‐Del2 predicted a worse overall survival in patients with HCC. Elevated PDSS2‐Del2 expression
Autor:
Kimberley Joanne Hatfield, Håkon Reikvam, Øystein Bruserud, Sushma Bartaula-Brevik, Ida Sofie Grønningsæter, Tor Henrik Anderson Tvedt, Elise Aasebø
Publikováno v:
Cells
Cells, Vol 9, Iss 1155, p 1155 (2020)
Volume 9
Issue 5
Cells, Vol 9, Iss 1155, p 1155 (2020)
Volume 9
Issue 5
Acute myeloid leukemia (AML) is an aggressive blood cancer resulting in accumulation of immature, dysfunctional blood cells in the bone marrow. Changes in cell metabolism are features of many cancers, including AML and this may be exploited as a ther
Autor:
Elena Ratner, Alessandro D. Santin, Laura J. Havrilesky, Osama Abdelghany, Amanda N. Fader, Angeles Alvarez Secord, Dan-Arin Silasi, Eric R. Siegel, Stefania Bellone, David M. O'Malley, K. ElSahwi, Babak Edraki, Pei Hui, Dana M. Roque, Masoud Azodi, Dirk Pikaart, Natalia Buza, Babak Litkouhi, Setsuko K. Chambers, Paul Celano, Nicole S. Nevadunsky, Floor J. Backes, William J. Lowery, Peter E. Schwartz
Publikováno v:
Clin Cancer Res
Purpose: Uterine-serous-carcinoma (USC) is an aggressive variant of endometrial cancer. On the basis of preliminary results of a multicenter, randomized phase II trial, trastuzumab (T), a humanized-mAb targeting Her2/Neu, in combination with carbopla
Autor:
Ryota Tamura, Yukina Morimoto, Kenzo Kosugi, Mizuto Sato, Yumiko Oishi, Ryo Ueda, Ryogo Kikuchi, Hideaki Nagashima, Tetsuro Hikichi, Shinobu Noji, Yutaka Kawakami, Hikaru Sasaki, Kazunari Yoshida, Masahiro Toda
Publikováno v:
BMC Cancer
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
Background The expression of vascular endothelial growth factor (VEGF)-A/ VAGF receptors (VEGFRs) signaling plays a pivotal role in the tumor angiogenesis and the development of the immunosuppressive tumor microenvironment in glioblastomas. We have p
Autor:
Jie Ge, Xin Li, Christopher I. Amos, Eunyoung Cho, Jeffrey E. Lee, Qingyi Wei, Hongliang Liu, Hongmei Nan, Sheng Luo, Hua Yuan, Ning Gu, Wei Dai
Publikováno v:
Eur J Cancer
BACKGROUND: Cutaneous melanoma (CM) is the most lethal type of skin cancers. Nicotinamide adenine dinucleotide phosphate (NADPH) plays an important role in anabolic reactions and tumorigenesis, but many genes are involved in the NADPH system. METHODS