Zobrazeno 241 - 250
of 18 481
pro vyhledávání: ''
Autor:
Isabelle S. Csete, Ross L. Levine, Qi Gao, Alexander Chan, Andriy Derkach, Maximilian Stahl, Sheng F. Cai, Jinjuan Yao, Tanmay Mishra, Richard Koche, Sophia Yanis, Martin S. Tallman, Aaron D Goldberg, Michael R. Waarts, Raajit K. Rampal, Ahmet Dogan, Robert L. Bowman, Minal Patel, Ying Liu, Wenbin Xiao, Mikhail Roshal, Maria E. Arcila, Jeeyeon Baik, Nicole L. DelGaudio, Christopher Famulare, Yanming Zhang
Publikováno v:
Blood
Plasmacytoid dendritic cells (pDCs) are the principal natural type I interferon–producing dendritic cells. Neoplastic expansion of pDCs and pDC precursors leads to blastic plasmacytoid dendritic cell neoplasm (BPDCN), and clonal expansion of mature
Autor:
Larry Z. Zheng, Jessica Yancey, Linda Ding, Jennifer K. Yates, Kriti Mittal, Yang Zong, Zhong Jiang, Jesse N. Aronowitz, Thomas J. Fitzgerald
Publikováno v:
American Journal of Clinical Oncology. 44:175-180
Introduction Hematuria can be a distressing and debilitating complication of urothelial carcinoma (UC) of the kidney for patients who are not candidates for surgery or ureteroscopic ablation. We retrospectively assessed the efficacy, tolerability, an
Autor:
Zhihong Chi, Li Zhou, Bin Lian, Bixia Tang, Hong Yao, Jun Guo, Lu Si, Lili Mao, Chuanliang Cui, Xue Bai, Xuan Wang, Siming Li, Xieqiao Yan, Yan Kong, Xinan Sheng, Jie Dai
Publikováno v:
Journal of Clinical Oncology. 39:881-889
PURPOSE Mucosal melanoma (MM) is a highly vascularized tumor with an extremely poor prognosis. In this randomized, open-label, phase II study, we characterized the efficacy and safety of bevacizumab in combination with carboplatin plus paclitaxel (CP
Autor:
Satoshi Yoda, Wafa Malik, Adam Langenbucher, Justin F. Gainor, Sai-Hong Ignatius Ou, Kylie Prutisto-Chang, Ramin Sakhtemani, Jennifer L Peterson, Aaron N. Hata, Alexander Drilon, Andrew Do, Jessica J. Lin, Adam J. Schoenfeld, Viola W. Zhu, Ted William Johnson, Jochen K. Lennerz, Lecia V. Sequist, Noura J. Choudhury, Ibiayi Dagogo-Jack, Subba R. Digumarthy, Christina Falcon, Charlotte E. Lee, Alice T. Shaw, Michael S. Lawrence, Beow Y. Yeap, Jennifer S. Temel, Harper Hubbeling
Publikováno v:
Clin Cancer Res
Purpose: Current standard initial therapy for advanced, ROS proto-oncogene 1, receptor tyrosine kinase fusion (ROS1)-positive (ROS1+) non–small cell lung cancer (NSCLC) is crizotinib or entrectinib. Lorlatinib, a next-generation anaplastic lymphoma
Autor:
Peng Wei, Ying Wang, Donjeta Gjuka, Jing Wang, Jorge A. Marrero, Jingjing Jiao, Laura Beretta, Hashem B. El-Serag, Xiaoling Song, Ilvira M. Khan
Publikováno v:
Cancer Prev Res (Phila)
Novel biomarkers for hepatocellular carcinoma (HCC) surveillance in patients with cirrhosis are urgently needed. We previously identified osteopontin (OPN) as a promising biomarker for the early detection of HCC. This study is to further validate the
Autor:
Kinya Nagata, Masayuki Nagasawa, Masakatsu Yanagimachi, Tetsuya Fukuda, Noriko Mitsuiki, Tomohiro Morio, Masahide Yamamoto, Akira Igarashi, Osamu Miura, Ryutaro Oba
Publikováno v:
International Journal of Hematology. 113:910-920
We have recently reported a new method for detecting T-cell-derived extracellular vesicles (EVs), CD3+CD4+EVs,CD3+CD8+EVs, and CD3+HLA-DR+EVs. In our previous study, CD3+HLA-DR+EVs were released profusely by CD8+T cells, only moderately by T helper1
Autor:
Sapna Pradyuman Patel, David S. Hong, Vivek Subbiah, Amanda Johnston, Siqing Fu, John S. Bomalaski, Sarina Anne Piha-Paul, Shuyang Yao, Ahmed Kaseb, Aung Naing, Nai Shi, Filip Janku, Apostolia Maria Tsimberidou, Shannon N. Westin, John Stewart
Publikováno v:
Br J Cancer
Background Arginine depletion interferes with pyrimidine metabolism and DNA damage-repair pathways, and pairing arginine deiminase pegylated with 20,000-molecular-weight polyethylene glycol (ADI-PEG20) with platinum enhances cytotoxicity in vitro and
Autor:
Yun Chen Huang, Pei Chi Hou, Che Yuan Hu, Hsiu Chi Lee, Chien-Hui Ou, Shih Chieh Lin, Yi Syuan Lin, Chad J. Creighton
Publikováno v:
Oncogene
Metastatic castration-resistant prostate cancer (mCRPC) is a malignant and lethal disease caused by relapse after androgen-deprivation (ADT) therapy. Since enzalutamide is innovated and approved by US FDA as a new treatment option for mCRPC patients,
Autor:
Takanori Yamashita, Mototsugu Shimokawa, Yuka Oku, Naoki Haratake, Fumihiko Kinoshita, Keisuke Kosai, Tomoyoshi Takenaka, Yuki Ono, Naoki Nakashima, Gouji Toyokawa, Tetsuzo Tagawa, Masaki Mori, Sho Wakasu
Publikováno v:
Anticancer Research. 41:1621-1628
Background/aim Albumin-bilirubin (ALBI) grade is an indicator of liver dysfunction and is useful for predicting postoperative prognosis of hepatocellular carcinomas. However, the significance of ALBI grade in non-small cell lung carcinoma (NSCLC) has
Autor:
Akihiro Ohmoto, Naoki Fukuda, Kazuhisa Toda, Hiroki Mitani, Naomi Hayashi, Kenji Nakano, Shunji Takahashi, Yasuyoshi Sato, Junichi Tomomatsu, Makiko Ono, Tetsuya Urasaki, Xiaofei Wang
Publikováno v:
Anticancer Research. 41:1683-1691
BACKGROUND/AIM Lenvatinib is standard therapy for radioiodine-refractory differentiated thyroid cancer (RR-DTC), although the optimal timing for starting treatment is still controversial. The aim of this study was to evaluate the prognostic impact of