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Autor:
Ghlichloo, Ida, Jin, Zhongbo, Fan, Ruohao, Tong, Caili, Starostik, Petr, Chien, Jeremy R, Lai, Jinping
Publikováno v:
In Vivo
In vivo (Athens, Greece), vol 36, iss 1
In vivo (Athens, Greece), vol 36, iss 1
Background/Aim: It is estimated that nonmelanoma skin cancer (NMSC), including basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), affects more than 3 million Americans each year. Translation of next-generation sequencing (NGS) data into id
Autor:
Yoshihiro Komohara, Toshiyuki Shima, Masayuki Shimoda, Remi Mito, Yusuke Shinchi, Koei Ikeda, Makoto Suzuki, Takuro Sakagami, Eri Matsubara, Yae Kanai, Yukio Fujiwara
Publikováno v:
Pathology International. 71:666-673
CD163 is one of the scavenger receptors expressed on macrophages. However, several immunohistochemical studies have demonstrated that CD163 is also detected on cancer cells, and is associated with a poor prognosis. In the present study, we detected C
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 29:693-699
Glypican 3 (GPC3) is a cell membrane protein and plays a dual role, as a tumor suppressor and oncogene, depending on its structure. It is known to regulate the Wnt/β-catenin signaling pathway and affect cell growth and proliferation. β-catenin play
Autor:
Keshava K Datta, Ravindra Kumar, Anshuman Dixit, Rupesh Dash, Samapika Routray, Vinuth N Puttamallesh, Aditi Chatterjee, Neeta Mohanty, Harsha Gowda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Oral squamous cell carcinoma (OSCC) is known for its aggressiveness associated with poor prognosis. The molecular mechanisms underlying the invasion and metastasis are still poorly understood. An improved understanding of these mechanisms shall prece
Autor:
Bingqing Yan, Siwei Zhang, Fangjia Tong, Huanhuan Xie, Lianhao Song, Lanlan Wei, Bozhi Wang, Tianyang Liu, Siyang Yu, Fen Ma
Publikováno v:
Cancer Science
Human papillomavirus (HPV) is an important etiological factor of head and neck squamous cell carcinoma (HNSCC). HPV+ HNSCC patients usually have a better prognosis, which probably results from the higher infiltration of B lymphocytes. This study was
Autor:
Jang-Hee Kim, Sun Il Kim, Bumhee Park, Se Joong Kim, Nam Hoon Cho, Seol Ho Choo, Ji Su Kim, Jiyeon Han, Ji Eun Kwon, Sang Kyum Kim
Publikováno v:
Journal of Cancer Research and Clinical Oncology
BackgroundPenile carcinoma is a rare malignant neoplasm and its molecular pathogenetic mechanism is largely unknown. Telomerase reverse transcriptase (TERT) promoter mutations have been detected in several types of human malignancies, including malig
Publikováno v:
Anticancer Research. 41:101-111
Background/aim The expression of tumor-associated programmed death-ligand 1 (PD-L1) predicts clinical responses to PD-1-directed immunotherapy. The expression levels of PD-L2, another PD-1 ligand, and its relationship with responses to PD-1-targeting
Autor:
Mariana Petaccia de Macedo, Carlos Barrios, Eduardo Caetano Albino da Silva, Gustavo Werutsky, Clovis Klock, G. Borges, Christina Shiang, Fernando Silva de Moura, Vladmir Cláudio Cordeiro de Lima, Luiz H. Araujo, Eldsamira Mascarenhas, Paulo Ricardo Santos Nunes Filho, Pedro De Marchi, Helano C. Freitas, Facundo Zaffaroni, Patricia Pacheco Viola, A. Gelatti, Lisandro Ferreira Lopes, Mauro Zukin, Ana Maria Franco Gaiger, Clarissa Mathias
Publikováno v:
Clinical Lung Cancer. 21:e511-e515
Introduction We analyzed the prevalence of non–small-cell lung cancer (NSCLC) with a programmed cell death ligand 1 (PD-L1) tumor proportion score (TPS) of ≥ 50% and compared the results with the existing data from clinical trials and databases f
Autor:
Veronica Pompei, Anna Campanati, Davide Sartini, Monica Mattioli-Belmonte, Tiziana Bacchetti, Annamaria Offidani, Monica Emanuelli, Valerio Brisigotti, Gianna Ferretti, Guendalina Lucarini, Elisa Molinelli, Roberto Campagna, Eleonora Salvolini
Publikováno v:
Human Cell. 34:1929-1931
Publikováno v:
Journal of Obstetrics and Gynaecology. 41:785-790
Cervical cancer is the most prevalent cancer among women in India. The main cause of cervical cancer is persistent human papilloma viral (HPV) infection. HPV inactivates the pRb tumour suppressor protein; thus p16 expression, which is controlled by a