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Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
BMC Cancer
BMC Cancer
Background This study aimed to comprehensively investigate the effect of spread through air spaces (STAS) on clinicopathologic features, molecular characteristics, immunohistochemical expression, and prognosis in lung adenocarcinomas (ADC) and squamo
Autor:
Ya-Jie Tang, Xiao Yang, Xin-hua Liang, Ya-ling Tang, Sha-sha Wang, Min Zheng, Xin Pang, Mei Zhang, Xiao-lei Gao, Jia-Shun Wu, Jing-biao Wu, Xiang-hua Yu
Publikováno v:
Molecular Carcinogenesis. 58:1809-1821
Macrophage migration inhibitory factor (MIF) has been shown to closely associate with the malignant progression of a variety of human carcinomas. However, the role and its underlying molecular mechanisms of MIF in the invasion and metastasis of oral
Autor:
Agustí Toll, Evelyn Andrades, Ramon M. Pujol, Vicenç García-Patos, Eugenia Hernández-Ruiz, Mireia Yébenes, Javier Gimeno, Carla Ferrándiz-Pulido, Irene García-Díez, Inmaculada Hernández-Muñoz
Publikováno v:
The American Journal of Dermatopathology. 40:647-654
Programmed cell death ligand 1 (PD-L1) expression by tumor cells plays an important role in the inhibition of T cell-mediated immune response in cancer. PD-L1 expression by tumor cells has been linked to poor prognosis in a wide variety of cancers. H
Autor:
Mari K. Halle, Marte Sødal, Hilde Engerud, David Forsse, Bjørn I. Bertelsen, Camilla Krakstad, Ingfrid S. Haldorsen, Kari Strøno Wagner-Larsen, Njål G. Lura, Jone Trovik, Kathrine Woie, Akinyemi I. Ojesina
Publikováno v:
British Journal of Cancer
Background Advanced cervical cancer carries a particularly poor prognosis, and few treatment options exist. Identification of effective molecular markers is vital to improve the individualisation of treatment. We investigated transcriptional data fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::839b54a851051f73e14419c2d53c21d6
https://hdl.handle.net/11250/2830881
https://hdl.handle.net/11250/2830881
Autor:
Claudio Roberto Cernea, Marco Aurélio Vamondes Kulcsar, Fatima Solange Pasini, Thérèse Rachell Theodoro, Evandro Sobroza de Mello, Marina de Menezes Ishikawa, Rogério Aparecido Dedivitis, Luiz Paulo Kowalski, Maria Aparecida da Silva Pinhal, Gilberto Mendes Menderico Junior, Raquel Ajub Moyses, Andrômeda Aryane Bomtempo Ribeiro, Leandro Luongo de Matos
Publikováno v:
Oral oncology. 110
The objective of the present study was to evaluate the role of microRNA-mediated remodeling of the extracellular matrix in the process of tumor invasion of oral squamous cell carcinoma and to evaluate its relationship with the prognosis of these pati
Publikováno v:
Pathology oncology research : POR. 26(4)
The accurate preoperative determination of the extent of mandibular resection remains a challenge for the surgeons. The purpose of the present study was to immunohistochemically investigate predictive markers for histological bone invasion of oral sq
Autor:
Tuula Salo, Elias Sundquist, Priscila Campioni Rodrigues, Maria Siponen, Marlene Vierthaler, Maija Risteli
Oral tongue squamous cell carcinoma (OTSCC), the most common cancer in the oral cavity, is aggressive and its incidence is increasing globally. Human host defense cationic antimicrobial peptide-18/antimicrobial peptide leucine-leucine-37 (hCAP18/LL-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dc61b1c59d594f32b4d382ca7135fd0
http://urn.fi/urn:nbn:fi-fe2020061042527
http://urn.fi/urn:nbn:fi-fe2020061042527
Autor:
Jinah Kim, Sumaira Z. Aasi, John B. Sunwoo, Carolyn S. Lee, Misha Amoils, Vasu Divi, A. Dimitrios Colevas, S. Tyler Hollmig, Yifei Ma
Publikováno v:
Otolaryngology–Head and Neck Surgery. 160:93-99
To characterize programmed death-ligand 1 (PD-L1) expression and tumor-infiltrating lymphocyte (TIL) positivity for locally aggressive or regionally metastatic cutaneous head and neck squamous cell carcinoma (cHNSCC).Retrospective chart review, follo
Autor:
Teppei Jinno, Seiji Nakamura, H. Tanaka, Kazunari Oobu, Tamotsu Kiyoshima, Naoki Kaneko, Takeshi Toyoshima, Ryoji Kitamura, Masafumi Moriyama, Yasuyuki Maruse, Ryota Matsubara, Yuma Hashiguchi, Yuichi Goto, Taiki Sakamoto, Shintaro Kawano
Publikováno v:
International Journal of Oral and Maxillofacial Surgery. 47:836-845
Programmed cell death ligand 1 (PD-L1) and its receptor PD-1 are immune checkpoint molecules that attenuate the immune response. Blockade of PD-L1 enhances the immune response in a variety of tumours and thus serves as an effective anti-cancer treatm
Autor:
Emily Bellile, Nisha J. D'Silva, Ronald C. Inglehart, Nickole Russo, Min Liu, Lauren J. Beesley, Jeremy M. G. Taylor, Ligia Buloto Schmitd, Gregory T. Wolf, Genevieve E. Romanowicz
Publikováno v:
Neoplasia (New York, N.Y.)
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 7, Pp 657-667 (2018)
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 7, Pp 657-667 (2018)
A diagnosis of perineural invasion (PNI), defined as cancer within or surrounding at least 33% of the nerve, leads to selection of aggressive treatment in squamous cell carcinoma (SCC). Recent mechanistic studies show that cancer and nerves interact