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Autor:
Efim Y Alekseenok, S V Sidorov, Dmitry Strunkin, Lyudmila F. Gulyaeva, T S Kalinina, Vladislav V Kononchuk, Darya Obukhova
Publikováno v:
Genes
Volume 12
Issue 4
Genes, Vol 12, Iss 582, p 582 (2021)
Volume 12
Issue 4
Genes, Vol 12, Iss 582, p 582 (2021)
In ~70% of breast cancer (BC) cases, estrogen and progesterone receptors (ER and PR) are overexpressed, which can change during tumor progression. Expression changes of these receptors during cancer initiation and progression can be caused by alterat
Autor:
Patricia H. J. van Cleef, Marian Stevens-Kroef, Iris D. Nagtegaal, Jeroen R. Dijkstra, Paul N. Span, Jolien Tol, Annet Simons, Susan Vermeulen, Peter Bult, Bastiaan B J Tops, Carlijn van de Water, Irene Otte-Höller, Dagmar Verweij, Margrethe Schlooz-Vries, Altuna Halilovic, Jeroen van der Laak, Janet Elsink, Oliver B. A. Boelens
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports, 9
Scientific Reports
Scientific Reports, 9
Breast cancer treatment depends on human epidermal growth factor receptor-2 (HER2) status, which is often determined using dual probe fluorescence in situ hybridisation (FISH). Hereby, also loss and gain of the centromere of chromosome 17 (CEP17) can
Autor:
Hee Jeong Kim, Junetae Kim, Byung Ho Son, Il Yong Chung, Sae Byul Lee, Guiyun Sohn, Beom Seok Ko, Jong Won Lee, Kyung Hae Jung, Sei Hyun Ahn, Jisun Kim
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose This preliminary study was conducted to evaluate the association between Oncotype DX (ODX) recurrence score and traditional prognostic factors. We also developed a nomogram to predict subgroups with low ODX recurrence scores (less than 25) an
Publikováno v:
Clinical and Translational Oncology. 22:468-473
The findings from the American College of Surgeons Oncology Group (ACOSOG) Z0011 trial have questioned the use of axillary lymph node (ALN) dissection (ALND) in breast cancer patients with low ALN burden. In this study, our aim was to evaluate axilla
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-10 (2019)
BMC Cancer
BMC Cancer
Background Sentinel node biopsy (SNB) is the standard procedure for axillary staging in patients with clinically lymph node negative invasive breast cancer. Completion axillary lymph node dissection (c-ALND) may not be necessary for all patients as a
Autor:
Poodt, Ingrid G. M., Schipper, Robert-Jan, de Greef, Bianca T. A., Vugts, Guusje, Maaskant-Braat, Adriana J. G., Jansen, Frits H., Wyndaele, Dirk N. J., Voogd, Adri C., Nieuwenhuijzen, Grard A. P., Roumen, R. M. H., Luiten, E. J. T., Rutgers, E. J. T., Vrancken-Peeters, M. T. F. D., Bessems, M., Klaase, J. M., Muller, S., Francken, A. B., Van Dalen, T., Koopal, S. A., Vissers, Y. L. J., Smidt, M. L., Merkus, J. W. S., Contant, C. M. E., Veldman, P. H., Linthorst-Niers, E. M. H., van der Sijp, J. R., Guicherit, O. R., Koppert, L. B., Bosch, A. M., Strobbe, L. J. A., Schlooz-Vries, M. S., Arntz, I. E., van Essen, J. A., de Waard, J. W. D., Vrouenraets, B. C., van Ooijen, B., Smidt, Marjolein
Publikováno v:
Breast Cancer Research and Treatment, 175(2), 419-428. SPRINGER
Breast Cancer Research and Treatment, 175, 2, pp. 419-428
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 175(2), 419-428. Springer, Cham
Breast Cancer Research and Treatment, 175(2), 419-428. Springer New York
Breast Cancer Research and Treatment, 175, 419-428
Breast Cancer Research and Treatment, 175, 2, pp. 419-428
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, 175(2), 419-428. Springer, Cham
Breast Cancer Research and Treatment, 175(2), 419-428. Springer New York
Breast Cancer Research and Treatment, 175, 419-428
Purpose In patients with ipsilateral breast tumor recurrence (IBTR), the detection of distant disease determines whether the intention of the treatment is curative or palliative. Therefore, adequate preoperative staging is imperative for optimal trea
Autor:
Matthew J. Ellis, Sara M. Tolaney, Lisa A. Carey, Ian E. Krop, William T. Barry, Beverly Moy, Chau T. Dang, Denise A. Yardley, Clifford A. Hudis, P. Kelly Marcom, Beth Overmoyer, Ann H. Partridge, Eric P. Winer, Jennifer R. Bellon, Kathy S. Albain, Antonio C. Wolff, Hope S. Rugo, Hao Guo, Harold J. Burstein
Publikováno v:
Breast Cancer Research and Treatment. 176:303-310
Women with HER2-positive breast cancer treated prior to effective anti-HER2 therapy have higher rates of local–regional recurrence (LRR) than those with HER2-negative disease. Effective systemic therapy, however, has been shown to decrease LRR. Thi
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose The purpose of this study was to detect the lymphatic drainage pattern of internal mammary area and verify the concept of internal mammary sentinel lymph node (IM-SLN) in breast. Materials and methods A small particle radiotracer (99mTc-Dextr
Publikováno v:
Cancer Biomarkers. 24:363-370
BACKGROUND AND OBJECTIVE Dysregulation of DNA polymerase iota (Pol ι) in breast cancer might contribute to the accumulation of genomic mutations and promotes breast cancer progression. In this study we explored the clinical relevance and biological
Autor:
Dinesh Chandra Doval, Ljubomir Buturovic, Chandra Prakash, Manjiri M Bakre, Chetana Basavaraj, Arun Kumar Attuluri, S. P. Somashekhar, Charusheila Ramkumar, Lekshmi Madhav, Prathima R, Sudeep Gupta, Nirupama Naidu, Mark D. Pegram
Publikováno v:
Cancer Medicine, Vol 8, Iss 4, Pp 1755-1764 (2019)
Cancer Medicine
Cancer Medicine
CanAssist‐Breast (CAB) is an immunohistochemistry (IHC)‐based prognostic test for early‐stage Hormone Receptor (HR+)‐positive breast cancer patients. CAB uses a Support Vector Machine (SVM) trained algorithm which utilizes expression levels o