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Publikováno v:
Cancer Biomarkers. 24:363-370
BACKGROUND AND OBJECTIVE Dysregulation of DNA polymerase iota (Pol ι) in breast cancer might contribute to the accumulation of genomic mutations and promotes breast cancer progression. In this study we explored the clinical relevance and biological
Publikováno v:
Cancer Science
Tumor necrosis factor receptor-associated factor 6 (TRAF6) has been found to be involved in carcinogenesis in multiple cancers. However, the precise role of TRAF6 in cancer has not been extensively investigated and remains largely unknown. In this st
Autor:
Massimo Cristofanilli, Jozef Mardiak, Tatiana Sedlackova, Denisa Manasova, Daniel Pindak, Katarina Kalavska, Gabriel Minarik, Juraj Benca, James M. Reuben, Jurisova Silvia, Michal Mego, Marian Karaba
Publikováno v:
Anticancer Research. 39:1829-1837
Background/aim Circulating tumor cells (CTCs) comprise a heterogeneous population of cancer cells with different clinical and biological value. The aim of this study was to evaluate the prognostic value of CTCs with an epithelial-mesenchymal transiti
Autor:
Kenji Tezuka, Kosei Hirakawa, Shigehito Yamagata, Mao Tokumoto, Minoru Takada, Takeo Nishimori, Katsumi Ikeda, Shinya Tokunaga, Hidemi Kawajiri, Yoshinari Ogawa, Yoko Mizuyama, Takeshi Sunami, Tsutomu Takashima, Shinichiro Kashiwagi, Masaichi Ohira, Tetsuro Ishikawa, Shinzoh Kudoh, Satoru Noda, Shigehiko Nishimura
Publikováno v:
Anticancer Research. 39:2053-2059
Aim This study was conducted in order to evaluate the efficacy and safety of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus trastuzumab followed by 5-fluorouracil/ epirubicin/cyclophosphamide (FEC) in a neoadjuvant chemotherapy (NAC) set
Autor:
Ryohei Sasaki, Koichi Hirokaga, Toshinori Soejima, Shintaro Takao, Yoko Matsumoto, Mayuko Miki, Hiroki Kawaguchi, Yosuke Ota, Kayoko Tsujino
Publikováno v:
Japanese Journal of Clinical Oncology. 49:545-553
Objective To compare patient preferences and acute adverse events of hypofractionated (HF) and conventionally fractionated (CF) whole-breast irradiation (WBI) after breast-conserving surgery in our institution. Methods We conducted a patient preferen
Autor:
Yueping Liu, Junjun Liu, Zhe Zhang, Meiying Chui, Peiyi Xia, Xiaoyan Zhou, Ying Jia, Nengtai Ouyang, Wencai Li, Gang Chen, Peizhen Hu, Zhe Wang, Yi Shi, Junyi Ye, Hong Bu, Xiaojuan Li, Libo Yang, Longlong Bao, Feng Ye
Publikováno v:
Cancer Science
The correlation of genetic alterations with response to neoadjuvant chemotherapy (NAC) has not been fully revealed. In this study, we enrolled 247 breast cancer patients receiving anthracycline‐taxane‐based NAC treatment. A next generation sequen
Publikováno v:
Carcinogenesis. 40:537-543
The adenosine triphosphate-binding cassette (ABC) transporter superfamily consists of membrane proteins which translocate various substrates across membranes. Because ABCC11, a member ABC transporter, is highly expressed in breast cancer tissue, it m
Prognostic impact of TP53INP1 gene expression in estrogen receptor α-positive breast cancer patients
Autor:
Katsuhiro Okuda, Yu Dong, Satoru Takahashi, Tatsuya Toyama, Sayaka Nishikawa, Naoto Kondo, Tomoka Hisada, Yumi Wanifuchi-Endo, Mayumi Nishimoto, Hiroshi Sugiura, Hiroyuki Kato, Yukari Hato
Publikováno v:
Japanese Journal of Clinical Oncology. 49:567-575
BACKGROUND Tumor protein 53-induced nuclear protein 1 (TP53INP1) is a key stress protein with tumor suppressor function. Several studies have demonstrated TP53INP1 downregulation in many cancers. In this study, we investigated the correlations of TP5
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Aims: Death-associated protein kinase-1 (DAPK1) is a pro-apoptotic Ser/Thr kinase that participates in cell apoptosis and tumor suppression. DAPK1 is frequently lost in many different tumor types including breast cancer. The aim of this study was to
Publikováno v:
Oncology Reports
The aim of the present study was to investigate the potential anticancer effects of microRNA-216a on the growth of human breast cancer and the possible underlying mechanisms. The results demonstrated that serum microRNA-216a was significantly decreas