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Autor:
Li Zhu, Shuning Ding, Ou Huang, Weiguo Chen, Yafen Li, Weilin Chen, Xiaosong Chen, Jiayi Wu, Mengdi Chen, Caijin Lin, Deyue Liu, Kunwei Shen, Lisa Andriani, Jianrong He
Publikováno v:
Clinical Breast Cancer. 22:e147-e156
BACKGROUND In human epidermal growth factor receptor 2 (HER2)-positive breast cancer, emerging evidence imply that clinical behaviors differ according to hormone receptor (HR) status. However, there is no conclusion about the relevance between estrog
Autor:
Tina Pesaran, Jeffrey N. Weitzel, Clarice R. Weinberg, Chi Gao, Susan L. Neuhausen, Eric C. Polley, Alpa V. Patel, Christopher A. Haiman, Christine B. Ambrosone, Celine M. Vachon, Hongyan Huang, Sara Lindstrom, Julie R. Palmer, Esther M. John, Jill S. Dolinsky, Leslie Bernstein, Rohan Gnanaolivu, Allison W. Kurian, Steven N. Hart, Holly LaDuca, Hoda Anton-Culver, Janet E. Olson, Chunling Hu, Amal Yussuf, Song Yao, Nicole L. Larson, Peter Kraft, Jie Na, Fergus J. Couch, Nicholas J. Boddicker, Elena Martinez, Amy Trentham-Dietz, Siddhartha Yadav, Paul W. Auer, Dale R Sandler, Elizabeth C. Chao, Susan M. Domchek, Rachid Karam, Katherine L. Nathanson, James V. Lacey, Jack A. Taylor, David E. Goldgar
Publikováno v:
J Clin Oncol
PURPOSE To determine the contribution of germline pathogenic variants (PVs) in hereditary cancer testing panel genes to invasive lobular carcinoma (ILC) of the breast. MATERIALS AND METHODS The study included 2,999 women with ILC from a population-ba
Autor:
Hiroko Yamashita, Kanako C. Hatanaka, Toraji Amano, Yoshihiro Matsuno, Yutaka Hatanaka, Kanako Hagio
Publikováno v:
Breast, Vol 60, Iss, Pp 206-213 (2021)
The Breast : Official Journal of the European Society of Mastology
The Breast : Official Journal of the European Society of Mastology
Background Because a number of years may be required for normal cells to develop into carcinoma, genes involved in tumorigenesis and progression might differ among breast cancers in young women and those in older women. The present study sought to an
Autor:
Henriette Christgen, Laura Bollmann, Mieke Raap, Rachel Wuerstlein, Bahriye Aktas, Ronald E. Kates, Ulrike Nitz, Ulrich Lehmann, Monika Graeser, Oleg Gluz, Michael Braun, Hans Kreipe, Sherko Kuemmel, Claudia Schumacher, Matthias Christgen, Malte Gronewold, Stephan Bartels, Nadia Harbeck, Eva-Maria Grischke, Christine Eulenburg, Isabel Grote, Kerstin Luedtke-Heckenkamp, Leonie Kandt
Publikováno v:
Cancer Medicine, Vol 10, Iss 23, Pp 8581-8594 (2021)
Cancer Medicine
Cancer Medicine
Background Whereas the genomic landscape of endocrine‐resistant breast cancer has been intensely characterized in previously treated cases with local or distant recurrence, comparably little is known about genomic alterations conveying primary non
Autor:
Tawfiqul Bhuiya, Juan P. Idrovo, Jin Cao, Pooja Navale, Louis J. Auguste, Sudarshana Roychoudhury, Silvat Sheikh-Fayyaz, Hua Guo
Publikováno v:
Clinical Breast Cancer. 21:e638-e646
This study explored human papillomavirus (HPV) amplification in breast benign and malignant lesions by chromogenic in situ hybridization (CISH) and the concordance of p16 expression by immunohistochemistry.The presence of HPV6/11 and HPV16/18 in 33 c
Autor:
Satoru Noda, Tamami Morisaki, Yukio Miki, Naoyoshi Onoda, Tsutomu Takashima, Akitoshi Shimazaki, Daiju Ueda, Takashi Honjo, Shinichiro Kashiwagi, Akira Yamamoto
Publikováno v:
JCO Precision Oncology. :543-551
PURPOSE The molecular subtype of breast cancer is an important component of establishing the appropriate treatment strategy. In clinical practice, molecular subtypes are determined by receptor expressions. In this study, we developed a model using de
Autor:
Lauren R. Teras, Siddhartha Yadav, Amy Trentham-Dietz, Dale P. Sandler, James M. Hodge, Elena Ma Martínez, Fergus J. Couch, Jack A. Taylor, Katie M. O'Brien, Alpa V. Patel, Christopher A. Haiman, Chunling Hu, Mia M. Gaudet, David E. Goldgar, Paul W. Auer, James V. Lacey, Nicholas J. Boddicker, Sara Lindström, Celine M. Vachon, Susan L. Neuhausen, Irene M. Ong, Kimberly A. Bertrand, Leslie Bernstein, Loic Le Marchand, Eric C. Polley, Janet E. Olson, Hongyan Huang, Christine B. Ambrosone, Tina Pesaran, Susan M. Domchek, Amal Yussuf, Nicole L. Larson, Rohan Gnanaolivu, Brian D. Carter, Song Yao, Steven N. Hart, Holly LaDuca, Rachid Karam, Jie Na, Chi Gao, Katherine L. Nathanson, Peter Kraft, Elizabeth C. Chao, Huiyan Ma, Jeffrey N. Weitzel, Julie R. Palmer, Christopher E. Scott, Charles Kooperberg, Jill S. Dolinsky, David J. Hunter, Elizabeth S. Burnside
Publikováno v:
J Clin Oncol
PURPOSE The prevalence of germline pathogenic variants (PVs) in established breast cancer predisposition genes in women in the general population over age 65 years is not well-defined. However, testing guidelines suggest that women diagnosed with bre
Autor:
Man Feng, Chunmiao Ye, Yujuan Xiang, Zhong-Cheng Gao, Fei Wang, Shuya Huang, Zhigang Yu, Cheng-Jun Zhou, Wenzhong Zhou, Chao Zheng, Mingming Guo, Liyuan Liu, Xiaoxia Zhang, Gengshen Yin, Ling-Yu Kong, Dianshui Sun, Lei Wang
Publikováno v:
International Journal of Cancer. 150:705-717
Because of the high heterogeneity of breast cancer outcome, identification of novel prognostic biomarkers is critical to improve patient stratification and guide precise treatment. We examined the prognostic value of gamma-interferon-inducible lysoso
Publikováno v:
Int J Cancer
High nut consumption is associated with reduced total and certain cause-specific mortality in general populations. However, its association with cancer outcomes among long-term breast cancer survivors remains unknown. We examined the associations of
Autor:
Yansong Liu, Xinzhao Wang, Chao Li, Xiaoli Bian, Zhaoyun Liu, Xiang Song, Wei Zhao, Zhiyong Yu
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 23, Pp 8352-8364 (2021)
Cancer Medicine, Vol 10, Iss 23, Pp 8352-8364 (2021)
The previous studies had demonstrated the promising effectiveness and acceptable safety of pyrotinib in patients with HER2‐positive metastatic breast cancer. We aimed to investigate the real‐world data of pyrotinib in complex clinical practice an