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Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Autor:
C. Meyer, Y. Fouché, Emmanuel Chamorey, M. Dejode, C. Bailleux, J. Haudebourg, Renaud Schiappa, Y. Delpech, Emmanuel Barranger
Publikováno v:
Clinical Breast Cancer. 22:121-126
Background Delays in initiating adjuvant chemotherapy after breast cancer surgery seems to have an impact on patients’ risk of relapse and their survival rate. The aim of this retrospective study was to identify factors delaying initiation of adjuv
Autor:
Ashley J. Schlafstein, Karen D. Godette, Shannon Kahn, Mylin A. Torres, Subir Goyal, Jolinta Lin, Trevor J. Royce, Sagar A. Patel, Yuan Liu
Publikováno v:
Clinical Breast Cancer. 22:127-135
Neoadjuvant chemotherapy (NAC) is increasingly used for operable breast cancer (BC). Appropriate radiation therapy (RT) fields (ie, whole breast [WB] ± regional nodal irradiation [RNI]) in patients who were clinically node positive (cN1) but convert
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:40-51
The omission of radiation therapy (RT) in older women with stage 1 estrogen-receptor-positive (ER+) breast cancer receiving endocrine therapy (ET) is an acceptable strategy based on randomized trial data. Less is known about the omission of ET with o
Autor:
Henriette Christgen, Laura Bollmann, Mieke Raap, Rachel Wuerstlein, Bahriye Aktas, Ronald E. Kates, Ulrike Nitz, Ulrich Lehmann, Monika Graeser, Oleg Gluz, Michael Braun, Hans Kreipe, Sherko Kuemmel, Claudia Schumacher, Matthias Christgen, Malte Gronewold, Stephan Bartels, Nadia Harbeck, Eva-Maria Grischke, Christine Eulenburg, Isabel Grote, Kerstin Luedtke-Heckenkamp, Leonie Kandt
Publikováno v:
Cancer Medicine, Vol 10, Iss 23, Pp 8581-8594 (2021)
Cancer Medicine
Cancer Medicine
Background Whereas the genomic landscape of endocrine‐resistant breast cancer has been intensely characterized in previously treated cases with local or distant recurrence, comparably little is known about genomic alterations conveying primary non
Autor:
Linu Abraham Jacob, M C Suresh Babu, Smitha Saldanha, L K Rajeev, A H Rudresha, K N Lokesh, Usha Amirtham, A. Thottian, D. Lokanatha, Shina Goyal
Publikováno v:
Breast Disease. 41:115-121
BACKGROUND: The present era of individualized treatment for breast cancer is influenced by the initial disease status including the anatomical extent, grade, and receptor status. An accurate preoperative staging is the basis of treatment planning and
Publikováno v:
Molecular Biology Reports. 49:531-537
Signal recognition particle (SRP) promotes co-translational translocation of the proteins through or into the endoplasmic reticulum membrane and it also has elongation arrest function. SRP9 is one of the six protein subunits of SRP and functions in e
Autor:
Jodi A. Kagihara, Elizabeth Molina, Lavanya Kondapalli, Peter Kabos, Jennifer R. Diamond, Cathy J. Bradley, Megan Eguchi, Elisabeth Meyer, Christine M. Fisher, Anna R Schreiber
Publikováno v:
Breast Cancer Research and Treatment
Purpose Adjuvant chemotherapy reduces recurrence in early-stage triple-negative breast cancer (TNBC). However, data are lacking evaluating anthracycline + taxane (ATAX) versus taxane-based (TAX) chemotherapy in older women with node-negative TNBC, as
Publikováno v:
Int J Cancer
High nut consumption is associated with reduced total and certain cause-specific mortality in general populations. However, its association with cancer outcomes among long-term breast cancer survivors remains unknown. We examined the associations of
Autor:
Christoph Röcken, HM Behrens, F. W. Schäfer, L.-J. Kramp, M. van Mackelenbergh, Micaela Mathiak
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background We explored the hypothesis that high-quality standards in diagnostic mammography can lead to an early diagnosis of breast cancers and identifies at risk populations outside screening programs. The histopathological features and distributio